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Tissue biopsy of an orbital mass was highly characteristic of IgG4-RD histology and a rapid clinical response to corticosteroids was observed. This case highlights IgG4-RD as a rare cause of intraocular inflammation that may progress to involve the orbit.<\/jats:p>","DOI":"10.1136\/bcr-2017-219568","type":"journal-article","created":{"date-parts":[[2017,4,24]],"date-time":"2017-04-24T04:49:01Z","timestamp":1493009341000},"page":"bcr-2017-219568","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":17,"title":["IgG4-related disease presenting as posterior scleritis and vitritis, progressing to multifocal orbital involvement"],"prefix":"10.1136","volume":"2017","author":[{"given":"Gavin L","family":"Reynolds","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonathan H","family":"Norris","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sher","family":"Aslam","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Srilakshmi","family":"Sharma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2017,4,23]]},"reference":[{"key":"2025042705563186000_2017.apr23_1.bcr-2017-219568.1","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1016\/j.crad.2013.09.021","article-title":"Extrapancreatic findings of IgG4-related disease","volume":"69","author":"Tan","year":"2014","journal-title":"Clin Radiol"},{"key":"2025042705563186000_2017.apr23_1.bcr-2017-219568.2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM200103083441005"},{"key":"2025042705563186000_2017.apr23_1.bcr-2017-219568.3","doi-asserted-by":"publisher","DOI":"10.1111\/j.1442-2042.2006.01568.x"},{"key":"2025042705563186000_2017.apr23_1.bcr-2017-219568.4","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0b013e3181c811ad"},{"key":"2025042705563186000_2017.apr23_1.bcr-2017-219568.5","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2559.2011.04089.x"},{"key":"2025042705563186000_2017.apr23_1.bcr-2017-219568.6","doi-asserted-by":"publisher","DOI":"10.1038\/modpathol.2012.72"},{"key":"2025042705563186000_2017.apr23_1.bcr-2017-219568.7","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1155\/2013\/532612","article-title":"IgG4-Related disease","volume":"2013","author":"Stone","year":"2013","journal-title":"Int J Rheumatol"},{"key":"2025042705563186000_2017.apr23_1.bcr-2017-219568.8","doi-asserted-by":"publisher","DOI":"10.1136\/bjophthalmol-2015-307437"},{"key":"2025042705563186000_2017.apr23_1.bcr-2017-219568.9","doi-asserted-by":"crossref","first-page":"168","DOI":"10.3109\/09273948.2014.985384","article-title":"IgG4-related disease masquerading as recurrent scleritis and chronic conjunctivitis","volume":"23","author":"Philippakis","year":"2015","journal-title":"Ocul Immunol Inflamm"},{"key":"2025042705563186000_2017.apr23_1.bcr-2017-219568.10","doi-asserted-by":"crossref","unstructured":"Lee CS , Harocopos GJ , Kraus CL , et al . 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