{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T18:06:39Z","timestamp":1789927599739,"version":"4.0.1"},"reference-count":9,"publisher":"BMJ","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Reports"],"accepted":{"date-parts":[[2017,8,1]]},"abstract":"<jats:p>A 56-year-old male with cirrhosis presented with acute bleeding from cardiofundal gastroesophageal varices (GOV) and was treated with endoscopic cyanoacrylate glue. Glue therapy achieved stabilisation of the patient in the emergent setting. Three months later, the patient suffered rebleeding. At that time, he underwent retreatment with balloon-occluded retrograde obliteration (BRTO), with no recurrence at a follow-up of 14 months.<\/jats:p>\n               <jats:p>Available treatments for bleeding GOV include methods to (a) directly obstruct the varices (endoscopic variceal ligation , sclerotherapy and cyanoacrylate glue, BRTO) or to (b) decrease portal pressure (surgical portacaval shunts; transportal intrahepatic portosystemic shunt). No precise guidelines are available regarding when to use which modality, and few centres have experience with all of them. This case report illustrates a setting in which both options of cyanoacrylate glue therapy and BRTO were used for acute gastric variceal bleeding.<\/jats:p>","DOI":"10.1136\/bcr-2017-219615","type":"journal-article","created":{"date-parts":[[2017,8,11]],"date-time":"2017-08-11T11:16:23Z","timestamp":1502450183000},"page":"bcr-2017-219615","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":3,"title":["Therapeutic options for bleeding oesophageal varices: cyanoacrylate and balloon-occluded retrograde obliteration (BRTO)"],"prefix":"10.1136","volume":"2017","author":[{"given":"Helena L","family":"Frischtak","sequence":"first","affiliation":[{"name":"School of Medicine, University of Virginia, Charlottesville, Virginia, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jessica P","family":"Davis","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Hepatology, Department of Medicine, University of Virginia, Charlottesville, Virginia, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Neeral L","family":"Shah","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Hepatology, Department of Medicine, University of Virginia, Charlottesville, Virginia, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2017,8,11]]},"reference":[{"key":"2025082703342746000_2017.aug11_1.bcr-2017-219615.1","doi-asserted-by":"crossref","first-page":"314","DOI":"10.5604\/16652681.1198800","article-title":"Management of gastroesophageal varices in cirrhotic patients: current status and future directions","volume":"15","author":"Toshikuni","year":"2016","journal-title":"Ann Hepatol"},{"key":"2025082703342746000_2017.aug11_1.bcr-2017-219615.2","doi-asserted-by":"publisher","DOI":"10.1002\/hep.21907"},{"key":"2025082703342746000_2017.aug11_1.bcr-2017-219615.3","doi-asserted-by":"crossref","first-page":"115","DOI":"10.15403\/jgld.2014.1121.251.mcc","article-title":"Isolated gastric varices and use of balloon-occlusive retrograde transvenous obliteration: a case report and literature review","volume":"25","author":"McCarty","year":"2016","journal-title":"J Gastrointestin Liver Dis"},{"key":"2025082703342746000_2017.aug11_1.bcr-2017-219615.4","doi-asserted-by":"crossref","first-page":"1784","DOI":"10.1038\/ajg.2012.160","article-title":"Gastric varices: is there a role for endoscopic cyanoacrylates, or are we entering the BRTO era?","volume":"107","author":"Caldwell","year":"2012","journal-title":"Am J Gastroenterol"},{"key":"2025082703342746000_2017.aug11_1.bcr-2017-219615.5","doi-asserted-by":"publisher","DOI":"10.1136\/flgastro-2013-100428"},{"key":"2025082703342746000_2017.aug11_1.bcr-2017-219615.6","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v17.i11.1494"},{"key":"2025082703342746000_2017.aug11_1.bcr-2017-219615.7","doi-asserted-by":"publisher","DOI":"10.1053\/jhep.2001.24116"},{"key":"2025082703342746000_2017.aug11_1.bcr-2017-219615.8","doi-asserted-by":"crossref","first-page":"1164","DOI":"10.1016\/j.gie.2015.09.040","article-title":"EUS-guided treatment of gastric fundal varices with combined injection of coils and cyanoacrylate glue: a large U.S. experience over 6 years (with video)","volume":"83","author":"Bhat","year":"2016","journal-title":"Gastrointest Endosc"},{"key":"2025082703342746000_2017.aug11_1.bcr-2017-219615.9","doi-asserted-by":"crossref","first-page":"1543","DOI":"10.1007\/s10620-014-3485-8","article-title":"Balloon-occluded retrograde transvenous obliteration (BRTO) for treatment of gastric varices: review and meta-analysis","volume":"60","author":"Park","year":"2015","journal-title":"Dig Dis Sci"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2017-219615","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T10:34:35Z","timestamp":1756290875000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2017-219615"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,8,11]]},"references-count":9,"alternative-id":["10.1136\/bcr-2017-219615"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2017-219615","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,8,11]]}}}