{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,29]],"date-time":"2025-08-29T09:49:42Z","timestamp":1756460982030,"version":"3.44.0"},"reference-count":8,"publisher":"BMJ","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Reports"],"accepted":{"date-parts":[[2017,6,2]]},"abstract":"<jats:p>A 56-year-old man with a history of injection drug use and two prior episodes of native valve infective endocarditis presented with dyspnoea on exertion. Our preliminary work-up revealed bacteraemia with reported growth of \u2018<jats:italic>Mycobacterium abscessus<\/jats:italic> group\u2019 on multiple blood cultures. The patient was later found to have eustachian valve and prosthetic pulmonic valve endocarditis. Initially, he responded to standard antimycobacterial therapy for rapidly growing mycobacteria (RGM) with supporting laboratory susceptibilities. However, he later developed refractory disease and persistent bacteraemia in the setting of these alleged susceptible antibiotics. Further molecular testing revealed a functional and inducible <jats:italic>erm(<\/jats:italic>41) gene which confers macrolide resistance. A subspecies analysis of the <jats:italic>M abscessus<\/jats:italic> group revealed the subspecies to be <jats:italic>abscessus<\/jats:italic>. We present a challenging case of <jats:italic>M abscessus<\/jats:italic> subsp. <jats:italic>abscessus<\/jats:italic> bacteraemia and prosthetic valve endocarditis with further discussion on treatment and management of this infection along with the taxonomic complexity of this ubiquitous RGM.<\/jats:p>","DOI":"10.1136\/bcr-2017-219618","type":"journal-article","created":{"date-parts":[[2017,6,13]],"date-time":"2017-06-13T04:45:23Z","timestamp":1497329123000},"page":"bcr-2017-219618","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":5,"title":["A rare case of <i>Mycobacterium abscessus<\/i> subspecies <i>abscessus<\/i> prosthetic valve endocarditis and the clinical importance of inducible <i>erm<\/i>(41) gene testing"],"prefix":"10.1136","volume":"2017","author":[{"given":"Norman","family":"Beatty","sequence":"first","affiliation":[{"name":"Department of Medicine, Division of Infectious Diseases, University of Arizona College of Medicine, Tucson, Arizona, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Craig","family":"Brown","sequence":"additional","affiliation":[{"name":"Department of Medicine, Division of Infectious Diseases, University of Arizona College of Medicine, Tucson, Arizona, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tirdad","family":"Zangeneh","sequence":"additional","affiliation":[{"name":"Department of Medicine, Division of Infectious Diseases, University of Arizona College of Medicine, Tucson, Arizona, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mayar","family":"Al Mohajer","sequence":"additional","affiliation":[{"name":"Department of Medicine, Baylor College of Medicine,Division of Infectious Diseases, Houston, Texas, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2017,6,13]]},"reference":[{"key":"2025082805344311000_2017.jun13_1.bcr-2017-219618.1","doi-asserted-by":"publisher","DOI":"10.1038\/jid.1953.18"},{"key":"2025082805344311000_2017.jun13_1.bcr-2017-219618.2","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.15.4.716-746.2002"},{"key":"2025082805344311000_2017.jun13_1.bcr-2017-219618.3","doi-asserted-by":"crossref","unstructured":"Griffith DE . Mycobacterium abscessus subsp abscessus lung disease: 'trouble ahead, trouble behind\u2026'. F1000Prime Rep 2014;6.doi:10.12703\/P6-107","DOI":"10.12703\/P6-107"},{"key":"2025082805344311000_2017.jun13_1.bcr-2017-219618.4","doi-asserted-by":"crossref","first-page":"1638-46","DOI":"10.3201\/2109.141634","article-title":"Mycobacterium abscessus Complex Infections in Humans","volume":"21","author":"Lee","year":"2015","journal-title":"Emerg Infect Dis"},{"key":"2025082805344311000_2017.jun13_1.bcr-2017-219618.5","doi-asserted-by":"publisher","DOI":"10.1513\/AnnalsATS.201501-015OI"},{"key":"2025082805344311000_2017.jun13_1.bcr-2017-219618.6","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.01275-08"},{"key":"2025082805344311000_2017.jun13_1.bcr-2017-219618.7","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00861-10"},{"key":"2025082805344311000_2017.jun13_1.bcr-2017-219618.8","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(12)70316-X"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2017-219618","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T12:34:51Z","timestamp":1756384491000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2017-219618"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,6,13]]},"references-count":8,"alternative-id":["10.1136\/bcr-2017-219618"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2017-219618","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2017,6,13]]}}}