{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T10:40:04Z","timestamp":1756377604433,"version":"3.44.0"},"reference-count":9,"publisher":"BMJ","funder":[{"name":"Grants-in-Aid for Research from the National Center for Global Health and Medicine"}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Reports"],"accepted":{"date-parts":[[2017,6,6]]},"abstract":"<jats:p>Central nervous system immune reconstitution inflammatory syndrome (CNS-IRIS), which occurs most often in HIV-infected patients, is an exacerbation of inflammatory reactions related to opportunistic infections as well as primary CNS malignancies both of which mostly occur in HIV-infected patients. However, differential diagnoses are challenging both clinically and radiologically. We describe a patient with CNS-IRIS due to toxoplasmosis whose <jats:sup>11<\/jats:sup>C-methionine uptake suggested lymphoma but whose arterial spin-labelling MRI led to the correct diagnosis.<\/jats:p>","DOI":"10.1136\/bcr-2017-219860","type":"journal-article","created":{"date-parts":[[2017,7,6]],"date-time":"2017-07-06T23:50:11Z","timestamp":1499385011000},"page":"bcr-2017-219860","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":1,"title":["Contribution of arterial spin-labelling MRI in a case with immune reconstitution inflammatory syndrome"],"prefix":"10.1136","volume":"2017","author":[{"given":"Noriaki","family":"Wada","sequence":"first","affiliation":[{"name":"Department of Radiology, Kokuritsu Kokusai Iryo Center Byoin, Shinjuku-ku, Tokyo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomoyuki","family":"Noguchi","sequence":"additional","affiliation":[{"name":"Department of Radiology, Kokuritsu Kokusai Iryo Center Byoin, Shinjuku-ku, Tokyo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takahiro","family":"Aoki","sequence":"additional","affiliation":[{"name":"Department of AIDS Clinical Center, Kokuritsu Kokusai Iryo Center Byoin, Shinjuku-ku, Tokyo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tsuyoshi","family":"Tajima","sequence":"additional","affiliation":[{"name":"Department of Radiology, Kokuritsu Kokusai Iryo Center Byoin, Shinjuku-ku, Tokyo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2017,7,6]]},"reference":[{"key":"2025082803012924000_2017.jul06_2.bcr-2017-219860.1","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(10)70026-8"},{"key":"2025082803012924000_2017.jul06_2.bcr-2017-219860.2","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciu270"},{"key":"2025082803012924000_2017.jul06_2.bcr-2017-219860.3","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1016\/j.parint.2014.05.007","article-title":"Clinical presentation and diagnosis of toxoplasmic encephalitis in Japan","volume":"63","author":"Sakamoto","year":"2014","journal-title":"Parasitol Int"},{"key":"2025082803012924000_2017.jul06_2.bcr-2017-219860.4","doi-asserted-by":"publisher","DOI":"10.1007\/s12149-010-0356-z"},{"key":"2025082803012924000_2017.jul06_2.bcr-2017-219860.5","first-page":"1162","article-title":"Carbon-11-methionine and fluorine-18-FDG PET study in brain hematoma","volume":"35","author":"Dethy","year":"1994","journal-title":"J Nucl Med"},{"key":"2025082803012924000_2017.jul06_2.bcr-2017-219860.6","doi-asserted-by":"publisher","DOI":"10.1007\/s00234-012-1089-6"},{"key":"2025082803012924000_2017.jul06_2.bcr-2017-219860.7","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1007\/s10014-010-0001-5","article-title":"Primary central nervous system lymphoma in acquired immune deficiency syndrome mimicking toxoplasmosis","volume":"28","author":"Utsuki","year":"2011","journal-title":"Brain Tumor Pathol"},{"key":"2025082803012924000_2017.jul06_2.bcr-2017-219860.8","doi-asserted-by":"publisher","DOI":"10.1016\/S1053-8119(03)00232-5"},{"key":"2025082803012924000_2017.jul06_2.bcr-2017-219860.9","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1148\/radiographics.14.1.8128041","article-title":"Methionine PET for follow-up of radiation therapy of primary lymphoma of the brain","volume":"14","author":"Ogawa","year":"1994","journal-title":"Radiographics"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2017-219860","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T10:01:36Z","timestamp":1756375296000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2017-219860"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,7,6]]},"references-count":9,"alternative-id":["10.1136\/bcr-2017-219860"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2017-219860","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2017,7,6]]}}}