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As immunosuppressants could have been responsible for the prolonged activation of RSV, we converted everolimus to mycophenolate mofetil. After the conversion, RSV promptly disappeared, and her symptoms improved. We speculate that converting the immunosuppressant may be effective for prolonged RSV infection due to the different immunosuppressive mechanisms.<\/jats:p>","DOI":"10.1136\/bcr-2017-220342","type":"journal-article","created":{"date-parts":[[2017,8,3]],"date-time":"2017-08-03T05:55:18Z","timestamp":1501739718000},"page":"bcr-2017-220342","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":1,"title":["Converting everolimus to mycophenolate mofetil ameliorated prolonged respiratory syncytial virus infection in a child after heart transplantation"],"prefix":"10.1136","volume":"2017","author":[{"given":"Hidehiro","family":"Suginobe","sequence":"first","affiliation":[{"name":"Department of Paeditatrics, Osaka University Graduate School of Medicine, Suita, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nobutoshi","family":"Nawa","sequence":"additional","affiliation":[{"name":"Department of Paeditatrics, Osaka University Graduate School of Medicine, Suita, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hidekazu","family":"Ishida","sequence":"additional","affiliation":[{"name":"Department of Paeditatrics, Osaka University Graduate School of Medicine, Suita, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shigetoyo","family":"Kogaki","sequence":"additional","affiliation":[{"name":"Department of Paeditatrics, Osaka University Graduate School of Medicine, Suita, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2017,8,3]]},"reference":[{"key":"2025082802202057000_2017.aug02_1.bcr-2017-220342.1","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.13.3.371-384.2000"},{"key":"2025082802202057000_2017.aug02_1.bcr-2017-220342.2","doi-asserted-by":"publisher","DOI":"10.1016\/j.idc.2010.01.007"},{"key":"2025082802202057000_2017.aug02_1.bcr-2017-220342.3","doi-asserted-by":"publisher","DOI":"10.1111\/tid.12409"},{"key":"2025082802202057000_2017.aug02_1.bcr-2017-220342.4","doi-asserted-by":"publisher","DOI":"10.1111\/petr.12022"},{"key":"2025082802202057000_2017.aug02_1.bcr-2017-220342.5","first-page":"723407","article-title":"Respiratory syncytial virus pneumonia treated with lower-dose palivizumab in a heart transplant recipient","volume":"2012","author":"Grodin","year":"2012","journal-title":"Case Rep Cardiol"},{"key":"2025082802202057000_2017.aug02_1.bcr-2017-220342.6","doi-asserted-by":"publisher","DOI":"10.1093\/clinids\/21.2.376"},{"key":"2025082802202057000_2017.aug02_1.bcr-2017-220342.7","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1111\/tid.12510","article-title":"Current practices for treatment of respiratory syncytial virus and other non-influenza respiratory viruses in high-risk patient populations: a survey of institutions in the Midwestern Respiratory Virus Collaborative","volume":"18","author":"Beaird","year":"2016","journal-title":"Transpl Infect Dis"},{"key":"2025082802202057000_2017.aug02_1.bcr-2017-220342.8","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.00090-16"},{"key":"2025082802202057000_2017.aug02_1.bcr-2017-220342.9","doi-asserted-by":"publisher","DOI":"10.1016\/S1526-0542(04)90023-1"},{"key":"2025082802202057000_2017.aug02_1.bcr-2017-220342.10","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.177.9.6263"},{"key":"2025082802202057000_2017.aug02_1.bcr-2017-220342.11","doi-asserted-by":"publisher","DOI":"10.1016\/j.it.2016.08.009"},{"key":"2025082802202057000_2017.aug02_1.bcr-2017-220342.12","doi-asserted-by":"publisher","DOI":"10.1111\/irv.12242"},{"key":"2025082802202057000_2017.aug02_1.bcr-2017-220342.13","doi-asserted-by":"publisher","DOI":"10.1053\/jlts.2001.24645"},{"key":"2025082802202057000_2017.aug02_1.bcr-2017-220342.14","doi-asserted-by":"crossref","first-page":"1178","DOI":"10.1002\/j.1875-9114.1997.tb03082.x","article-title":"Mycophenolate mofetil","volume":"17","author":"Sievers","year":"1997","journal-title":"Pharmacotherapy"},{"key":"2025082802202057000_2017.aug02_1.bcr-2017-220342.15","doi-asserted-by":"crossref","first-page":"1158","DOI":"10.1016\/j.healun.2016.08.017","article-title":"The Registry of the International Society for Heart and Lung Transplantation: Thirty-third Adult Heart Transplantation Report-2016; 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