{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,27]],"date-time":"2025-04-27T13:40:03Z","timestamp":1745761203792,"version":"3.40.4"},"reference-count":18,"publisher":"BMJ","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Reports"],"accepted":{"date-parts":[[2017,5,9]]},"abstract":"<jats:p>IgG<jats:sub>4<\/jats:sub>-related disease (IgG<jats:sub>4<\/jats:sub>-RD) is a rare form of autoimmune sclerosing disease, characterised by elevated serum IgG<jats:sub>4<\/jats:sub>and tissue IgG<jats:sub>4<\/jats:sub>levels, specific histopathological findings, multiorgan involvement and adequate response to glucocorticoid treatment. The low incidence and the heterogeneous nature of the disease has made consensus on diagnostic criteria for IgG<jats:sub>4<\/jats:sub>-RD difficult. Whether sclerosing mesenteritis (SM) is considered a manifestation of IgG<jats:sub>4<\/jats:sub>-RD is strongly debated. We present the case of a patient with a history of rheumatoid arthritis who presented with a calcified abdominal mass. She was found to have an isolated, pedunculated mesenteric mass positive for IgG<jats:sub>4<\/jats:sub>and concurrently elevated serum IgG<jats:sub>4<\/jats:sub>levels. Clinical features did not classify her disease as either SM or IgG<jats:sub>4<\/jats:sub>-RD as currently described in consensus statements. Concurrent diagnoses of IgG<jats:sub>4<\/jats:sub>-RD, SM and other autoimmune disorders, as well as postoperative recommendations for resected isolated IgG<jats:sub>4<\/jats:sub>-positive masses, are discussed.<\/jats:p>","DOI":"10.1136\/bcr-2017-220400","type":"journal-article","created":{"date-parts":[[2017,6,8]],"date-time":"2017-06-08T14:55:18Z","timestamp":1496933718000},"page":"bcr-2017-220400","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":3,"title":["Surgical management of isolated mesenteric autoimmune disease: addressing the spectrum of IgG<sub>4<\/sub>-related disease and sclerosing mesenteritis"],"prefix":"10.1136","volume":"2017","author":[{"given":"Alissa","family":"Greenbaum","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nour","family":"Yadak","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Steven","family":"Perez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ashwani","family":"Rajput","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2017,6,8]]},"reference":[{"key":"2025042706223136000_2017.jun08_1.bcr-2017-220400.1","doi-asserted-by":"crossref","DOI":"10.1097\/MD.0000000000001275","article-title":"IgG4-related disease: results from a multicentre Spanish registry","volume":"94","author":"Fern\u00e1ndez-Codina","year":"2015","journal-title":"Medicine"},{"key":"2025042706223136000_2017.jun08_1.bcr-2017-220400.2","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1053\/j.sult.2013.12.002","article-title":"IgG4-related disease in the abdomen: a great mimicker","volume":"35","author":"Al Zahrani","year":"2014","journal-title":"Semin Ultrasound CT MR"},{"key":"2025042706223136000_2017.jun08_1.bcr-2017-220400.3","doi-asserted-by":"publisher","DOI":"10.1038\/modpathol.2012.72"},{"key":"2025042706223136000_2017.jun08_1.bcr-2017-220400.4","doi-asserted-by":"crossref","first-page":"1203","DOI":"10.1016\/j.autrev.2014.08.013","article-title":"The clinical spectrum of IgG4-related disease","volume":"12","author":"Briton-Zer\u00f3n","year":"2014","journal-title":"Autoimmun Rev"},{"key":"2025042706223136000_2017.jun08_1.bcr-2017-220400.5","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1111\/pin.12386","article-title":"Sclerosing mesenteritis: a real manifestation or histological mimic of IgG4-related disease?","volume":"66","author":"Avincsal","year":"2016","journal-title":"Pathol Int"},{"key":"2025042706223136000_2017.jun08_1.bcr-2017-220400.6","doi-asserted-by":"crossref","unstructured":"Umehara H , Okazaki K , Kawano M , et al . 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