{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T07:10:07Z","timestamp":1756365007121,"version":"3.44.0"},"reference-count":12,"publisher":"BMJ","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Reports"],"accepted":{"date-parts":[[2017,7,13]]},"abstract":"<jats:p>A 24-year-old womanpresented with ameloblastic fibrosarcoma arising from ameloblastic fibroma. The delayed presentation accounted for the extensive destruction of the mandible and complete occlusion of her oral cavity. This resulted in an inability to eat and maintain oral hygiene. A multidisciplinary team management approach involved nutritional optimisation, segmental mandibulectomy, reconstruction with a reconstructive plate and a free anterolateral thigh flap to line the the floor of mouth. Functional and aesthetic outcome was acceptable, and the patient is planned for secondary free fibular flap bony reconstruction.<\/jats:p>","DOI":"10.1136\/bcr-2017-220436","type":"journal-article","created":{"date-parts":[[2017,8,1]],"date-time":"2017-08-01T03:37:32Z","timestamp":1501558652000},"page":"bcr-2017-220436","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["A delayed presentation of ameloblastic fibrosarcoma in an African patient"],"prefix":"10.1136","volume":"2017","author":[{"given":"Nkhensani Yvonne","family":"Chauke","sequence":"first","affiliation":[{"name":"Department of Plastic and Reconstructive Surgery, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, Gauteng, South Africa"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3438-508X","authenticated-orcid":false,"given":"Chrysis","family":"Sofianos","sequence":"additional","affiliation":[{"name":"Department of Plastic and Reconstructive Surgery, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, Gauteng, South Africa"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dimitri","family":"Liakos","sequence":"additional","affiliation":[{"name":"Department of Plastic and Reconstructive Surgery, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, Gauteng, South Africa"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elias","family":"Ndobe","sequence":"additional","affiliation":[{"name":"Department of Plastic and Reconstructive Surgery, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, Gauteng, South Africa"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2017,8,1]]},"reference":[{"key":"2025082723381040000_2017.jul31_1.bcr-2017-220436.1","doi-asserted-by":"publisher","DOI":"10.1016\/j.anorl.2013.03.001"},{"key":"2025082723381040000_2017.jul31_1.bcr-2017-220436.2","first-page":"173","article-title":"Ameloblastic fibrosarcoma: report of a case. immunohistochemical study and review of the literature","volume":"6","author":"Huguet","year":"2001","journal-title":"Med Oral"},{"key":"2025082723381040000_2017.jul31_1.bcr-2017-220436.3","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0757.2011.00393.x"},{"key":"2025082723381040000_2017.jul31_1.bcr-2017-220436.4","first-page":"1","article-title":"Ameloblastic fibrosarcoma of the mandible: a case report and brief review of the literature","volume":"2015","author":"Loya-Solis","year":"2015","journal-title":"Case Rep Pathol"},{"key":"2025082723381040000_2017.jul31_1.bcr-2017-220436.5","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcms.2005.04.006"},{"key":"2025082723381040000_2017.jul31_1.bcr-2017-220436.6","first-page":"112","article-title":"Ameloblastic fibrosarcoma of the upper jaw: report of a rare case with long-term follow-up","volume":"10","author":"Khalili","year":"2013","journal-title":"Dent Res J"},{"key":"2025082723381040000_2017.jul31_1.bcr-2017-220436.7","doi-asserted-by":"crossref","first-page":"548","DOI":"10.12659\/AJCR.892284","article-title":"Epithelial dysplasia in Ameloblastic Fibrosarcoma arising from recurrent ameloblastic fibroma in a 26-year-old Iranian man","volume":"16","author":"Mohsenifar","year":"2015","journal-title":"Am J Case Rep"},{"key":"2025082723381040000_2017.jul31_1.bcr-2017-220436.8","doi-asserted-by":"crossref","first-page":"e80","DOI":"10.1016\/j.tripleo.2008.07.031","article-title":"Rapid sarcomatous transformation of an ameloblastic fibroma of the mandible: case report and literature review","volume":"108","author":"Kousar","year":"2009","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol Endod"},{"key":"2025082723381040000_2017.jul31_1.bcr-2017-220436.9","first-page":"143","article-title":"Ameloblastic fibrosarcoma arising in the Maxilla","volume":"16","author":"Pillay","year":"2016","journal-title":"Ochsner J"},{"key":"2025082723381040000_2017.jul31_1.bcr-2017-220436.10","doi-asserted-by":"crossref","first-page":"1673","DOI":"10.1002\/1097-0142(197604)37:4<1673::AID-CNCR2820370410>3.0.CO;2-T","article-title":"Ameloblastic sarcoma: pathogenesis and treatment with chemotherapy","volume":"37","author":"Goldstein","year":"1976","journal-title":"Cancer"},{"key":"2025082723381040000_2017.jul31_1.bcr-2017-220436.11","doi-asserted-by":"crossref","first-page":"e72","DOI":"10.1097\/MPH.0b013e31821ba989","article-title":"Ameloblastic fibrosarcoma of the mandible: report of 2 chemosensitive pediatric cases","volume":"34","author":"Demoor-Goldschmidt","year":"2012","journal-title":"J Pediatr Hematol Oncol"},{"key":"2025082723381040000_2017.jul31_1.bcr-2017-220436.12","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1016\/j.bjoms.2015.12.014","article-title":"Reconstruction of 56 mandibular defects with autologous compressed particulate corticocancellous bone grafts","volume":"54","author":"Ferretti","year":"2016","journal-title":"Br J Oral Maxillofac Surg"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2017-220436","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T06:38:20Z","timestamp":1756363100000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2017-220436"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,8,1]]},"references-count":12,"alternative-id":["10.1136\/bcr-2017-220436"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2017-220436","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2017,8,1]]}}}