{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T04:16:08Z","timestamp":1790828168848,"version":"4.1.0"},"reference-count":24,"publisher":"BMJ","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Reports"],"accepted":{"date-parts":[[2017,7,4]]},"abstract":"<jats:p>Status asthmaticus (SA) is a life-threatening disorder. Severe respiratory failure may require extracorporeal membrane oxygenation (ECMO). Previous reports have demonstrated utility of ECMO in SA in various patients with varying success. A 25-year-old man was admitted with status asthmatics and severe hypercapnic respiratory failure. Despite tailored ventilator therapies, such as pressure control ventilation and maximal pharmacological therapy, including general anaesthesia, the patient\u00e2\u20ac\u2122s condition deteriorated rapidly. Veno-venous ECMO (VV-ECMO) was provided for respiratory support. The patient\u00e2\u20ac\u2122s clinical condition improved over the following 72\u00e2\u20ac\u2030hours and was discharged from the intensive care unit on day 3. This case report demonstrates the successful use of VV-ECMO in a patient with severe respiratory failure due to SA, who failed to respond to maximal therapy. This case adds support to a growing body of literature that shows that ECMO can be used with success for refractory status asthmaticus.<\/jats:p>","DOI":"10.1136\/bcr-2017-220693","type":"journal-article","created":{"date-parts":[[2017,7,28]],"date-time":"2017-07-28T03:50:22Z","timestamp":1501213822000},"page":"bcr-2017-220693","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":4,"title":["Adjunctive extracorporeal carbon dioxide removal in refractory status asthmaticus"],"prefix":"10.1136","volume":"2017","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1601-6854","authenticated-orcid":false,"given":"Chuan","family":"Jiang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jodi","family":"Galaydick","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Harold","family":"Fernandez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonathan","family":"Caronia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2017,7,27]]},"reference":[{"key":"2025042712165579000_2017.jul27_2.bcr-2017-220693.1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.200601-007OC"},{"key":"2025042712165579000_2017.jul27_2.bcr-2017-220693.2","unstructured":"National Heart, Lung, and Blood Institute, National Asthma Education and Prevention Program. Expert Panel Report 3: guidelines for thediagnosis and management of asthma: full report 2007. http:\/\/www.nhlbi.nih.gov\/guidelines\/asthma\/asthgdln.pdf (accessed July 2017)"},{"key":"2025042712165579000_2017.jul27_2.bcr-2017-220693.3","first-page":"110","article-title":"Measurement of air trapping, intrinsic positive end-expiratory pressure, and dynamic hyperinflation in mechanically ventilated patients","volume":"50","author":"Blanch","year":"2005","journal-title":"Respir Care"},{"key":"2025042712165579000_2017.jul27_2.bcr-2017-220693.4","first-page":"388","article-title":"Cardiovascular effects of mechanical ventilation","volume":"1","author":"Duke","year":"1999","journal-title":"Crit Care Resus"},{"key":"2025042712165579000_2017.jul27_2.bcr-2017-220693.5","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-009-1661-7"},{"key":"2025042712165579000_2017.jul27_2.bcr-2017-220693.6","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccc.2011.05.002"},{"key":"2025042712165579000_2017.jul27_2.bcr-2017-220693.7","first-page":"20","article-title":"Clinical review: severe asthma","volume":"26","author":"Papiris","year":"2000","journal-title":"Crit Care"},{"key":"2025042712165579000_2017.jul27_2.bcr-2017-220693.8","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(09)61069-2"},{"key":"2025042712165579000_2017.jul27_2.bcr-2017-220693.9","doi-asserted-by":"crossref","first-page":"S278","DOI":"10.1097\/01.CCM.0000233788.96388.D8","article-title":"Severe respiratory failure: advanced treatment options","volume":"34","author":"Hemmila","year":"2006","journal-title":"Crit Care Med"},{"key":"2025042712165579000_2017.jul27_2.bcr-2017-220693.10","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1542\/peds.76.4.479","article-title":"Extracorporeal circulation in neonatal respiratory failure: a prospective randomized study","volume":"76","author":"Bartlett","year":"1985","journal-title":"Pediatrics"},{"key":"2025042712165579000_2017.jul27_2.bcr-2017-220693.11","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(96)04100-1"},{"key":"2025042712165579000_2017.jul27_2.bcr-2017-220693.12","doi-asserted-by":"publisher","DOI":"10.1055\/s-0029-1231053"},{"key":"2025042712165579000_2017.jul27_2.bcr-2017-220693.13","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1979.03300200023016"},{"key":"2025042712165579000_2017.jul27_2.bcr-2017-220693.14","doi-asserted-by":"publisher","DOI":"10.1378\/chest.94.4.681"},{"key":"2025042712165579000_2017.jul27_2.bcr-2017-220693.15","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.149.2.8306022"},{"key":"2025042712165579000_2017.jul27_2.bcr-2017-220693.16","first-page":"161","article-title":"Extracorporeal life support for adult cardiorespiratory failure","volume":"114","author":"Anderson","year":"1993","journal-title":"Surgery"},{"key":"2025042712165579000_2017.jul27_2.bcr-2017-220693.17","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1986.03380070087025"},{"key":"2025042712165579000_2017.jul27_2.bcr-2017-220693.18","doi-asserted-by":"publisher","DOI":"10.1097\/MAT.0b013e3181901ea5"},{"key":"2025042712165579000_2017.jul27_2.bcr-2017-220693.19","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1177\/0267659116670481","article-title":"Extracorporeal membrane oxygenation support for life-threatening acute severe status asthmaticus","volume":"32","author":"Di Lascio","year":"2017","journal-title":"Perfusion"},{"key":"2025042712165579000_2017.jul27_2.bcr-2017-220693.20","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1007\/s00540-011-1288-z","article-title":"Successful treatment of severe asthma-associated plastic bronchitis with extracorporeal membrane oxygenation","volume":"26","author":"Tonan","year":"2012","journal-title":"J Anesth"},{"key":"2025042712165579000_2017.jul27_2.bcr-2017-220693.21","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1111\/crj.12252","article-title":"Low-flow veno-venous extracorporeal carbon dioxide removal in the management of severe status asthmatics: a case report","volume":"10","author":"Tiruvoipati","year":"2016","journal-title":"Clin Respir J"},{"key":"2025042712165579000_2017.jul27_2.bcr-2017-220693.22","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1080\/02770903.2016.1193871","article-title":"The use of life-saving extracorporeal membrane oxygenation (ECMO) for pregnant woman with status asthmaticus","volume":"54","author":"Steinack","year":"2017","journal-title":"J Asthma"},{"key":"2025042712165579000_2017.jul27_2.bcr-2017-220693.23","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1007\/s10047-016-0940-7","article-title":"ECMO for intractable status asthmaticus following atracurium","volume":"20","author":"Scaravilli","year":"2017","journal-title":"J Artif Organs"},{"key":"2025042712165579000_2017.jul27_2.bcr-2017-220693.24","doi-asserted-by":"crossref","first-page":"1437","DOI":"10.1007\/s00134-016-4452-y","article-title":"The feasibility and safety of extracorporeal carbon dioxide removal to avoid intubation in patients with COPD unresponsive to noninvasive ventilation for acute hypercapnic respiratory failure (ECLAIR\u00a0study): multicentre case-control study","volume":"42","author":"Braune","year":"2016","journal-title":"Intensive Care Med"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2017-220693","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,27]],"date-time":"2025-04-27T19:17:05Z","timestamp":1745781425000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2017-220693"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,7,27]]},"references-count":24,"alternative-id":["10.1136\/bcr-2017-220693"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2017-220693","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,7,27]]}}}