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Over the following months, he developed progressive dyspnoea. Lung function tests demonstrated severely reduced lung capacity with an obstructive pattern and a moderately reduced diffusion capacity. High resolution computer tomography revealed minor areas with tree-in-bud pattern and no signs of air trapping on expiratory views. Lung biopsy showed lymphocytic infiltration surrounding the bronchioles with sparing of the alveolar septa. He was diagnosed with follicular bronchiolitis. The patient spontaneously recovered along with an improvement of the immune system.<\/jats:p>","DOI":"10.1136\/bcr-2017-221025","type":"journal-article","created":{"date-parts":[[2017,11,30]],"date-time":"2017-11-30T00:55:14Z","timestamp":1512003314000},"page":"bcr-2017-221025","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":5,"title":["Follicular bronchiolitis in an HIV-infected individual on combination antiretroviral therapy with low CD4+ cell count but sustained viral suppression"],"prefix":"10.1136","volume":"2017","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0853-0893","authenticated-orcid":false,"given":"Line D","family":"Rasmussen","sequence":"first","affiliation":[{"name":"Department of Infectious Diseases, Odense University Hospital, Odense, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Court","family":"Pedersen","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases, Odense University Hospital, Odense, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Helle D","family":"Madsen","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine, Odense University Hospital, Odense, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christian B","family":"Laursen","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine, Odense University Hospital, Odense, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2017,11,29]]},"reference":[{"key":"2025082722085948000_2017.nov28_2.bcr-2017-221025.1","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1111\/resp.12385","article-title":"Lung function abnormalities in HIV-infected adults and children","volume":"20","author":"Calligaro","year":"2015","journal-title":"Respirology"},{"doi-asserted-by":"publisher","key":"2025082722085948000_2017.nov28_2.bcr-2017-221025.2","DOI":"10.7326\/0003-4819-132-5-200003070-00006"},{"doi-asserted-by":"publisher","key":"2025082722085948000_2017.nov28_2.bcr-2017-221025.3","DOI":"10.1378\/chest.130.5.1326"},{"doi-asserted-by":"publisher","key":"2025082722085948000_2017.nov28_2.bcr-2017-221025.4","DOI":"10.1097\/QAD.0000000000000283"},{"doi-asserted-by":"publisher","key":"2025082722085948000_2017.nov28_2.bcr-2017-221025.5","DOI":"10.1093\/cid\/cis933"},{"doi-asserted-by":"publisher","key":"2025082722085948000_2017.nov28_2.bcr-2017-221025.6","DOI":"10.1016\/0046-8177(92)90130-U"},{"doi-asserted-by":"publisher","key":"2025082722085948000_2017.nov28_2.bcr-2017-221025.7","DOI":"10.1378\/chest.91.1.63"},{"key":"2025082722085948000_2017.nov28_2.bcr-2017-221025.8","first-page":"956","article-title":"Lymphoid interstitial pneumonitis in acquired immunodeficiency syndrome-related complex","volume":"131","author":"Solal-Celigny","year":"1985","journal-title":"Am Rev Respir Dis"},{"key":"2025082722085948000_2017.nov28_2.bcr-2017-221025.9","first-page":"273","article-title":"Lymphocytic interstitial pneumonitis in adult HIV infection","volume":"88","author":"Lin","year":"1988","journal-title":"N Y State J Med"},{"key":"2025082722085948000_2017.nov28_2.bcr-2017-221025.10","first-page":"952","article-title":"Lymphocytic interstitial pneumonia associated with the acquired immune deficiency syndrome","volume":"131","author":"Grieco","year":"1985","journal-title":"Am Rev Respir Dis"},{"doi-asserted-by":"publisher","key":"2025082722085948000_2017.nov28_2.bcr-2017-221025.11","DOI":"10.1016\/S0046-8177(85)80155-6"},{"key":"2025082722085948000_2017.nov28_2.bcr-2017-221025.12","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1007\/s00408-003-1031-0","article-title":"Follicular bronchiolitis: clinical and pathologic findings in six patients","volume":"181","author":"Romero","year":"2003","journal-title":"Lung"},{"key":"2025082722085948000_2017.nov28_2.bcr-2017-221025.13","first-page":"Oe01","article-title":"Follicular Bronchiolitis: A Literature Review","volume":"9","author":"Tashtoush","year":"2015","journal-title":"J Clin Diagn Res"},{"key":"2025082722085948000_2017.nov28_2.bcr-2017-221025.14","doi-asserted-by":"crossref","first-page":"691","DOI":"10.5858\/134.5.691","article-title":"Update on nonneoplastic pulmonary lymphoproliferative disorders and related entities","volume":"134","author":"Guinee","year":"2010","journal-title":"Arch Pathol Lab Med"},{"doi-asserted-by":"publisher","key":"2025082722085948000_2017.nov28_2.bcr-2017-221025.15","DOI":"10.1055\/s-2001-17384"},{"doi-asserted-by":"publisher","key":"2025082722085948000_2017.nov28_2.bcr-2017-221025.16","DOI":"10.1002\/art.21980"},{"unstructured":"Centers for Disease Control\u00a0and Prevention. 1992. 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