{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T17:27:28Z","timestamp":1762018048869,"version":"3.44.0"},"reference-count":11,"publisher":"BMJ","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Reports"],"accepted":{"date-parts":[[2017,9,3]]},"abstract":"<jats:p>Unilateral adrenal metastases without disseminated disease has rarely been reported in differentiated thyroid carcinoma (DTC). A 72-year-old female presented with vague abdominal discomfort and loss of appetite of 2\u2009months duration. She had undergone left hemithyroidectomy for a benign thyroid nodule 18 years ago. A contrast CT of the abdomen showed a large left adrenal mass measuring 11\u00d79\u2009cm, suspicious of adrenocortical carcinoma. Hormonal evaluation was in keeping with a non-functional tumour. The patient underwent left adrenalectomy, histopathology of which revealed metastatic well-differentiated thyroid carcinoma. Ultrasound of thyroid done postoperatively showed a subcentimetric hypoechoic lesion with increased vascularity and microcalcifications in the right thyroid bed. Histopathology from a completion thyroidectomy specimen was consistent with follicular variant of papillary thyroid carcinoma. She was treated with high-dose radioiodine ablation therapy and has remained disease-free on follow-up for more than a year.<\/jats:p>","DOI":"10.1136\/bcr-2017-221296","type":"journal-article","created":{"date-parts":[[2017,9,27]],"date-time":"2017-09-27T08:30:17Z","timestamp":1506501017000},"page":"bcr-2017-221296","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":1,"title":["Unilateral adrenal mass as the sole initial manifestation of differentiated thyroid cancer"],"prefix":"10.1136","volume":"2017","author":[{"given":"Geethalakshmi","family":"Sampathkumar","sequence":"first","affiliation":[{"name":"Department of Endocrinology and Metabolism, Amrita Institute of Medical Sciences and Research Centre, Cochin, Kerala, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arun S","family":"Menon","sequence":"additional","affiliation":[{"name":"Department of Endocrinology and Metabolism, Amrita Institute of Medical Sciences and Research Centre, Cochin, Kerala, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bindhu","family":"M R","sequence":"additional","affiliation":[{"name":"Department of Pathology, Amrita Institute of Medical Sciences and Research Centre, Cochin, Kerala, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vasantha","family":"Nair","sequence":"additional","affiliation":[{"name":"Department of Endocrinology and Metabolism, Amrita Institute of Medical Sciences and Research Centre, Cochin, Kerala, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2017,9,27]]},"reference":[{"key":"2025082703132710000_2017.sep27_1.bcr-2017-221296.1","doi-asserted-by":"publisher","DOI":"10.1530\/ERC-14-0286"},{"key":"2025082703132710000_2017.sep27_1.bcr-2017-221296.2","doi-asserted-by":"crossref","first-page":"632","DOI":"10.1089\/thy.2016.0582","article-title":"Primary thyroid carcinoma with low-risk histology and distant metastases: clinicopathologic and molecular characteristics","volume":"27","author":"Xu","year":"2017","journal-title":"Thyroid"},{"key":"2025082703132710000_2017.sep27_1.bcr-2017-221296.3","doi-asserted-by":"crossref","unstructured":"See A , Iyer NG , Tan NC , et al . 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New York, USA: Springer Publishing, 2016:735\u201344.","DOI":"10.1007\/978-1-4939-3314-3_66"},{"key":"2025082703132710000_2017.sep27_1.bcr-2017-221296.7","first-page":"221","article-title":"Papillary thyroid carcinoma metastases presenting as ipsilateral adrenal mass and renal cyst","volume":"3","author":"Ginzburg","year":"2015","journal-title":"Urol Case Rep"},{"key":"2025082703132710000_2017.sep27_1.bcr-2017-221296.8","doi-asserted-by":"crossref","first-page":"11","DOI":"10.12970\/2310-9971.2015.03.01.3","article-title":"Adrenal metastases from thyroid cancers: three personal cases and literature review","volume":"3","author":"Chentli","year":"2015","journal-title":"J Endocrinol Diabetes Mellit"},{"key":"2025082703132710000_2017.sep27_1.bcr-2017-221296.9","doi-asserted-by":"crossref","first-page":"872","DOI":"10.1089\/thy.2016.0244","article-title":"Follicular variant of papillary thyroid carcinoma: hybrid or mixture?","volume":"26","author":"Daniels","year":"2016","journal-title":"Thyroid"},{"key":"2025082703132710000_2017.sep27_1.bcr-2017-221296.10","doi-asserted-by":"crossref","first-page":"983","DOI":"10.1089\/thy.2017.0079","article-title":"Low rate of noninvasive follicular thyroid neoplasm with papillary-like nuclear features in Asian practice","volume":"27","author":"Bychkov","year":"2017","journal-title":"Thyroid"},{"key":"2025082703132710000_2017.sep27_1.bcr-2017-221296.11","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1007\/s12022-015-9410-7","article-title":"Unusual thyroid carcinoma metastases: a case series and literature review","volume":"27","author":"Farina","year":"2016","journal-title":"Endocr Pathol"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2017-221296","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T10:13:36Z","timestamp":1756289616000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2017-221296"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,9,27]]},"references-count":11,"alternative-id":["10.1136\/bcr-2017-221296"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2017-221296","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2017,9,27]]}}}