{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T11:32:09Z","timestamp":1761823929873,"version":"3.44.0"},"reference-count":20,"publisher":"BMJ","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Reports"],"accepted":{"date-parts":[[2017,8,1]]},"abstract":"<jats:p>Renal cell carcinoma accounts for 3% of all adult malignancies. Usual sites of metastasis are lymph nodes, lungs, bone, liver and brain. We describe a patient who presented with complaints of holocranial headache and diplopia. MRI of the head showed a clival-based lesion with associated bony erosion. With suspicion of a metastatic lesion, an ultrasonogram of the abdomen was done which showed a left renal mass that enhanced on contrast-enhanced CT. There were no other metastatic foci. Patient underwent radiotherapy for the clival lesion. This case report emphasises on the evaluation of clival lesion with cranial neuropathies for a possibility of a renal primary tumour.<\/jats:p>","DOI":"10.1136\/bcr-2017-221570","type":"journal-article","created":{"date-parts":[[2017,8,11]],"date-time":"2017-08-11T10:05:20Z","timestamp":1502445920000},"page":"bcr-2017-221570","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":4,"title":["Isolated clival metastasis: a rare presentation of renal cell carcinoma"],"prefix":"10.1136","volume":"2017","author":[{"given":"Anil","family":"Mani","sequence":"first","affiliation":[{"name":"Department of Urology and Renal Transplant, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Priyank","family":"Yadav","sequence":"additional","affiliation":[{"name":"Department of Urology and Renal Transplant, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vimal Kumar","family":"Paliwal","sequence":"additional","affiliation":[{"name":"Department of Neurology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hira","family":"Lal","sequence":"additional","affiliation":[{"name":"Department of Radiology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2017,8,11]]},"reference":[{"key":"2025082722182589000_2017.aug10_2.bcr-2017-221570.1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2006.07.144"},{"key":"2025082722182589000_2017.aug10_2.bcr-2017-221570.2","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2010.10.029"},{"key":"2025082722182589000_2017.aug10_2.bcr-2017-221570.3","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mdr362"},{"key":"2025082722182589000_2017.aug10_2.bcr-2017-221570.4","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1016\/j.wneu.2016.12.078","article-title":"Clival metastasis of a duodenal Adenocarcinoma: a case report and literature review","volume":"100","author":"Dekker","year":"2017","journal-title":"World Neurosurg"},{"key":"2025082722182589000_2017.aug10_2.bcr-2017-221570.5","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(195105)4:3<610::AID-CNCR2820040312>3.0.CO;2-Q"},{"key":"2025082722182589000_2017.aug10_2.bcr-2017-221570.6","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.159.5.1414777"},{"key":"2025082722182589000_2017.aug10_2.bcr-2017-221570.7","doi-asserted-by":"crossref","first-page":"1285","DOI":"10.2214\/ajr.155.6.2122682","article-title":"MR imaging of the normal and abnormal clivus","volume":"155","author":"Kimura","year":"1990","journal-title":"AJR Am J Roentgenol"},{"key":"2025082722182589000_2017.aug10_2.bcr-2017-221570.8","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1159\/000331190","article-title":"Brain metastasis from renal cell carcinoma","volume":"25","author":"Kim","year":"2012","journal-title":"Prog Neurol Surg"},{"key":"2025082722182589000_2017.aug10_2.bcr-2017-221570.9","doi-asserted-by":"publisher","DOI":"10.3171\/2008.7.JNS08143"},{"key":"2025082722182589000_2017.aug10_2.bcr-2017-221570.10","doi-asserted-by":"crossref","DOI":"10.3171\/FOC.2008.25.12.E7","article-title":"Surgery for clival lesions: open resection versus the expanded endoscopic endonasal approach","volume":"25","author":"Carrabba","year":"2008","journal-title":"Neurosurg Focus"},{"key":"2025082722182589000_2017.aug10_2.bcr-2017-221570.11","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1016\/j.clinthera.2017.01.017","article-title":"Cost-effectiveness of pazopanib versus sunitinib as first-line treatment for locally advanced or metastatic renal cell carcinoma from an Italian National Health Service Perspective","volume":"39","author":"Capri","year":"2017","journal-title":"Clin Ther"},{"key":"2025082722182589000_2017.aug10_2.bcr-2017-221570.12","first-page":"51","article-title":"Management of side effects associated with sunitinib therapy for patients with renal cell carcinoma","volume":"2","author":"Schwandt","year":"2009","journal-title":"Onco Targets Ther"},{"key":"2025082722182589000_2017.aug10_2.bcr-2017-221570.13","doi-asserted-by":"crossref","first-page":"430","DOI":"10.3109\/02688697.2014.987217","article-title":"Endoscopic palliative decompression of the cavernous sinus in a rare case of a metastatic renal cell carcinoma to the clivus","volume":"29","author":"Mendelson","year":"2015","journal-title":"Br J Neurosurg"},{"key":"2025082722182589000_2017.aug10_2.bcr-2017-221570.14","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1055\/s-0033-1348027","article-title":"Metastatic disease to the clivus mimicking clival chordomas","volume":"74","author":"Deconde","year":"2013","journal-title":"J Neurol Surg B Skull Base"},{"key":"2025082722182589000_2017.aug10_2.bcr-2017-221570.15","first-page":"829","article-title":"[Skull base metastasis from renal cell carcinoma presenting as abducens nerve paresis: report of two cases]","volume":"24","author":"Sagoh","year":"1996","journal-title":"No Shinkei Geka"},{"key":"2025082722182589000_2017.aug10_2.bcr-2017-221570.16","first-page":"319","article-title":"[A case of renal cell carcinoma with metastasis in clivus presenting as diplopia]","volume":"44","author":"Fumino","year":"1998","journal-title":"Hinyokika Kiyo"},{"key":"2025082722182589000_2017.aug10_2.bcr-2017-221570.17","doi-asserted-by":"publisher","DOI":"10.2500\/105065899781389821"},{"key":"2025082722182589000_2017.aug10_2.bcr-2017-221570.18","doi-asserted-by":"crossref","first-page":"924","DOI":"10.2169\/internalmedicine.40.924","article-title":"Renal cell carcinoma with skull base metastasis preceded by paraneoplastic signs in a chronic hemodialysis patient","volume":"40","author":"Endo","year":"2001","journal-title":"Intern Med"},{"key":"2025082722182589000_2017.aug10_2.bcr-2017-221570.19","doi-asserted-by":"publisher","DOI":"10.1159\/000354575"},{"key":"2025082722182589000_2017.aug10_2.bcr-2017-221570.20","first-page":"1","article-title":"Unusual spread of renal cell Carcinoma to the clivus with cranial nerve deficit","volume":"2016","author":"Okudo","year":"2016","journal-title":"Case Rep Neurol Med"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2017-221570","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T05:18:36Z","timestamp":1756358316000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2017-221570"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,8,11]]},"references-count":20,"alternative-id":["10.1136\/bcr-2017-221570"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2017-221570","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2017,8,11]]}}}