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We report a case of a patient with CLL with no prior history of HSV infection, who presented with rapidly enlarging lymph nodes after initial response to idelalisib raising the suspicion of Richter\u2019s transformation. However, excisional biopsy of a lymph node revealed HSV adenitis along with CLL, which was confirmed by immunohistochemical staining.<\/jats:p>","DOI":"10.1136\/bcr-2017-222091","type":"journal-article","created":{"date-parts":[[2018,2,2]],"date-time":"2018-02-02T09:10:31Z","timestamp":1517562631000},"page":"bcr-2017-222091","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":5,"title":["Chronic lymphocytic leukaemia with necrotic herpetic adenitis: an elusive clinical condition"],"prefix":"10.1136","volume":"2018","author":[{"given":"Roma","family":"Srivastava","sequence":"first","affiliation":[{"name":"Department of Hematology\/Medical Oncology, Joan C Edwards School of Medicine at Marshall University, Huntington, West Virginia, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Doreen","family":"Griswold","sequence":"additional","affiliation":[{"name":"Department of Pathology, Joan C Edwards School of Medicine 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