{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,3]],"date-time":"2026-07-03T13:24:54Z","timestamp":1783085094366,"version":"3.54.6"},"reference-count":4,"publisher":"BMJ","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Reports"],"accepted":{"date-parts":[[2017,12,27]]},"abstract":"<jats:p>Seizures constitute a determining aspect in quality of life and are frequently challenging in palliative care\u2014a field where treatment has yet to be standardised. Levetiracetam\u2014a new generation anticonvulsant\u2014has proved efficacy both through oral, as well as intravenous administration in the general population. This case reports on the use of continuous subcutaneous levetiracetam to effectively control seizures in a terminally ill patient without patent oral route.<\/jats:p>","DOI":"10.1136\/bcr-2017-222340","type":"journal-article","created":{"date-parts":[[2018,1,19]],"date-time":"2018-01-19T00:25:23Z","timestamp":1516321523000},"page":"bcr-2017-222340","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":7,"title":["Continuous subcutaneous levetiracetam in end-of-life care"],"prefix":"10.1136","volume":"2018","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3985-0718","authenticated-orcid":false,"given":"In\u00eas","family":"Furtado","sequence":"first","affiliation":[{"name":"Medicine Department, Centro Hospitalar do Porto, Porto, Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fernando","family":"Gon\u00e7alves","sequence":"additional","affiliation":[{"name":"Medicine Department, Centro Hospitalar do Porto, Porto, Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jo\u00e3o","family":"Gon\u00e7alves","sequence":"additional","affiliation":[{"name":"Medicine Department, Centro Hospitalar do Porto, Porto, Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jo\u00e3o","family":"Neves","sequence":"additional","affiliation":[{"name":"Medicine Department, Centro Hospitalar do Porto, Porto, Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2018,1,18]]},"reference":[{"key":"2025082703090370000_2018.jan18_1.bcr-2017-222340.1","first-page":"379","article-title":"Management of Glioblastoma in the Elderly","volume":"10","author":"Sahebjam","year":"2012","journal-title":"Clin Adv Haematol Onc"},{"key":"2025082703090370000_2018.jan18_1.bcr-2017-222340.2","doi-asserted-by":"crossref","first-page":"371","DOI":"10.3109\/15360288.2014.959234","article-title":"Continuous subcutaneous use of levetiracetam: a retrospective review of tolerability and clinical effects","volume":"28","author":"R\u00e9mi","year":"2014","journal-title":"J Pain Palliat Care Pharmacother"},{"key":"2025082703090370000_2018.jan18_1.bcr-2017-222340.3","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpainsymman.2013.01.006"},{"key":"2025082703090370000_2018.jan18_1.bcr-2017-222340.4","doi-asserted-by":"crossref","unstructured":"Sutherland AE , Curtin J , Bradley V , et al . Subcutaneous levetiracetam for the management of seizures at the end of life. BMJ Support Palliat Care 2017.doi:10.1136\/bmjspcare-2016-001261","DOI":"10.1136\/bmjspcare-2016-001261"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2017-222340","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T10:09:15Z","timestamp":1756289355000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2017-222340"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,1,18]]},"references-count":4,"alternative-id":["10.1136\/bcr-2017-222340"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2017-222340","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,1,18]]}}}