{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T10:40:01Z","timestamp":1756291201185,"version":"3.44.0"},"reference-count":11,"publisher":"BMJ","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Reports"],"accepted":{"date-parts":[[2017,9,28]]},"abstract":"<jats:p>A 51-year-old man with no relevant medical history presents to the emergency department complaining of a recent worsening of few months upper abdominal pain with back radiation and postprandial fullness, without B symptoms. Laboratory analysis showed hyperamylasaemia, elevated lactate dehydrogenase and inflammatory parameters. Abdominal ultrasonography revealed a heterogeneous solid mass in the spleen\/splenic hilum with pancreatic parenchyma continuity and no biliary tract dilation or gallstones. A mild acalculous acute pancreatitis diagnosis was made. Abdominopelvic CT revealed a large heterogeneous mass infiltrating the spleen and pancreas and obstructing the common bile duct at the pancreatic level with upstream dilation of biliary and pancreatic ducts, with splenic vein invasion. Several necrotic, peripancreatic and hepatic hilar adenopathies were also observed. Ultrasound-guided biopsy showed a primary splenic diffuse large B-cell non-Hodgkin\u2019s lymphoma. Chemotherapy with R-CHOP (rituximab, cyclophosphamide, doxorubicin, vincristine and prednisolone) was performed with lack of response and the patient died within 10 months of diagnosis onset.<\/jats:p>","DOI":"10.1136\/bcr-2017-222643","type":"journal-article","created":{"date-parts":[[2017,10,10]],"date-time":"2017-10-10T07:00:09Z","timestamp":1507618809000},"page":"bcr-2017-222643","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":2,"title":["Acute pancreatitis as an unusual presentation of primary splenic lymphoma"],"prefix":"10.1136","volume":"2017","author":[{"given":"Elisa","family":"Gravito-Soares","sequence":"first","affiliation":[{"name":"Department of Gastroenterology, Centro Hospitalar e Universit\u00e1rio de Coimbra, Coimbra, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marta","family":"Gravito-Soares","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Centro Hospitalar e Universit\u00e1rio de Coimbra, Coimbra, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jos\u00e9 Eduardo","family":"Pina-Cabral","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Centro Hospitalar e Universit\u00e1rio de Coimbra, Coimbra, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luis","family":"Tom\u00e9","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Centro Hospitalar e Universit\u00e1rio de Coimbra and Faculty of Medicine, University of Coimbra, Coimbra, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2017,10,10]]},"reference":[{"key":"2025082703171533000_2017.oct09_2.bcr-2017-222643.1","doi-asserted-by":"publisher","DOI":"10.1038\/ajg.2013.218"},{"key":"2025082703171533000_2017.oct09_2.bcr-2017-222643.2","doi-asserted-by":"crossref","first-page":"3773","DOI":"10.3748\/wjg.v13.i27.3773","article-title":"Malignant lymphoma of spleen presenting as acute pancreatitis: a case report","volume":"13","author":"Wu","year":"2007","journal-title":"World J Gastroenterol"},{"key":"2025082703171533000_2017.oct09_2.bcr-2017-222643.3","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1016\/j.regg.2010.08.001","article-title":"[Splenic lymphoma presenting as acute pancreatitis in an 84 year-old patient. 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