{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,28]],"date-time":"2025-11-28T21:11:57Z","timestamp":1764364317134,"version":"3.44.0"},"reference-count":7,"publisher":"BMJ","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Reports"],"accepted":{"date-parts":[[2017,11,3]]},"abstract":"<jats:p>Umbilical artery catheterisation is frequently performed in preterm or critically ill newborn infants for invasive monitoring of blood pressure and blood sampling for laboratory tests. It is associated with well-known complications like catheter-related infections, thromboembolic events and aneurysmal formation of the aorta. In this report, we present another major complication of umbilical artery catheterisation: umbilical artery perforation. This complication occurred in a prematurely born infant and resulted in severe haemorrhagic shock, subsequent renal failure and severe periventricular leukomalacia. Ultimately, the patient deceased 3\u2009weeks after birth. Review of the literature identified only a few case reports and retrospective postmortem studies describing this complication. Neonatologists and paediatricians performing umbilical artery catheterisation should be aware of this rare, but potentially life-threatening complication.<\/jats:p>","DOI":"10.1136\/bcr-2017-222664","type":"journal-article","created":{"date-parts":[[2017,11,15]],"date-time":"2017-11-15T00:45:27Z","timestamp":1510706727000},"page":"bcr-2017-222664","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":10,"title":["Umbilical artery perforation: a potentially life-threatening complication of umbilical artery catheterisation"],"prefix":"10.1136","volume":"2017","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7540-6222","authenticated-orcid":false,"given":"Daniel","family":"Molanus","sequence":"first","affiliation":[{"name":"Department of Neonatology, VU University Medical Center, Amsterdam, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Machteld","family":"van Scherpenzeel","sequence":"additional","affiliation":[{"name":"Department of Neonatology, VU University Medical Center, Amsterdam, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joep","family":"Derikx","sequence":"additional","affiliation":[{"name":"Pediatric Surgical Center of Amsterdam, Emma Children\u2019s Hospital AMC & VU University Medical Center, Amsterdam, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Frank","family":"van den Dungen","sequence":"additional","affiliation":[{"name":"Department of Neonatology, VU University Medical Center, Amsterdam, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2017,11,14]]},"reference":[{"key":"2025082701183895000_2017.nov14_1.bcr-2017-222664.1","doi-asserted-by":"crossref","first-page":"975","DOI":"10.1542\/peds.30.6.975","article-title":"Pulmonary function in the newborn infant. 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Perfusion--estimation by analysis of the arterial-alveolar carbon dioxide difference","volume":"30","author":"Nelson","year":"1962","journal-title":"Pediatrics"},{"key":"2025082701183895000_2017.nov14_1.bcr-2017-222664.2","doi-asserted-by":"publisher","DOI":"10.1016\/j.clp.2004.11.005"},{"key":"2025082701183895000_2017.nov14_1.bcr-2017-222664.3","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.1975.01360160041006"},{"key":"2025082701183895000_2017.nov14_1.bcr-2017-222664.4","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3468(79)80482-0"},{"key":"2025082701183895000_2017.nov14_1.bcr-2017-222664.5","first-page":"296","article-title":"A rare complication of umbilical artery catheterization","volume":"47","author":"Powell","year":"1992","journal-title":"Br J Hosp Med"},{"key":"2025082701183895000_2017.nov14_1.bcr-2017-222664.6","first-page":"34","article-title":"Umbilical arterial rupture: a major complication of catheterization","volume":"78","author":"Sasidharan","year":"1985","journal-title":"Indiana Med"},{"key":"2025082701183895000_2017.nov14_1.bcr-2017-222664.7","doi-asserted-by":"crossref","first-page":"1028","DOI":"10.1542\/peds.44.6.1028","article-title":"Complications of umbilical vessel catheterization: peritoneal perforation","volume":"44","author":"Van leeuwen","year":"1969","journal-title":"Pediatrics"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2017-222664","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T08:18:50Z","timestamp":1756282730000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2017-222664"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,11,14]]},"references-count":7,"alternative-id":["10.1136\/bcr-2017-222664"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2017-222664","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2017,11,14]]}}}