{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T13:26:00Z","timestamp":1772112360057,"version":"3.50.1"},"reference-count":11,"publisher":"BMJ","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Reports"],"accepted":{"date-parts":[[2018,3,16]]},"abstract":"<jats:p>Intracranial hypertension is a rare entity in prepubertal children, and its differential diagnosis includes a number of systemic diseases, drugs, vitamin deficiencies and excesses, and hereditary conditions. Infectious aetiology is rare. The case of a 9-year-old boy with intracranial hypertension secondary to acute neuroborreliosis is described. He presented with daily pulsatile frontotemporal headache, pallor, photophobia and phonophobia. His neurological examination revealed papilledema with no nuchal rigidity. The lumbar puncture showed increased pressure (50\u2009cm H<jats:sub>2<\/jats:sub>O) and lymphocytic pleocytosis. Serum and cerebrospinal fluid (CSF) <jats:italic>Borrelia burgdorferi<\/jats:italic> antibodies were positive. This kind of infection is rare in Portugal but a trip to an endemic area was identified. A careful history, considering the exposure to rural areas together with the intracranial hypertension and inflammatory CSF, are important clues to the diagnosis, allowing the institution to select appropriate treatment.<\/jats:p>","DOI":"10.1136\/bcr-2017-222976","type":"journal-article","created":{"date-parts":[[2018,3,30]],"date-time":"2018-03-30T08:10:13Z","timestamp":1522397413000},"page":"bcr-2017-222976","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":10,"title":["Pseudotumor cerebri as the presentation of Lyme disease in a non-endemic area"],"prefix":"10.1136","volume":"2018","author":[{"given":"Marta","family":"Ezequiel","sequence":"first","affiliation":[{"name":"Department of Pediatria, Hospital Professor Doutor Fernando Fonseca, EPE, Amadora, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana Teresa","family":"Teixeira","sequence":"additional","affiliation":[{"name":"Department of Pediatria, Hospital Professor Doutor Fernando Fonseca, EPE, Amadora, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria Jo\u00e3o","family":"Brito","sequence":"additional","affiliation":[{"name":"Department of Pediatria, Hospital Professor Doutor Fernando Fonseca, EPE, Amadora, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Catarina","family":"Lu\u00eds","sequence":"additional","affiliation":[{"name":"Department of Pediatria, Hospital Professor Doutor Fernando Fonseca, EPE, Amadora, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2018,3,30]]},"reference":[{"key":"2025082701325520000_2018.mar29_2.bcr-2017-222976.1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejpn.2009.08.003"},{"key":"2025082701325520000_2018.mar29_2.bcr-2017-222976.2","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(07)70128-X"},{"key":"2025082701325520000_2018.mar29_2.bcr-2017-222976.3","doi-asserted-by":"crossref","DOI":"10.1212\/WNL.43.12.2609","article-title":"Neurologic manifestations in children with North American Lyme disease","volume":"43","author":"Belman","year":"1993","journal-title":"Neurology"},{"issue":"Suppl 40","key":"2025082701325520000_2018.mar29_2.bcr-2017-222976.4","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.ijmm.2005.12.003","article-title":"Clinical aspects of neuroborreliosis and post-Lyme disease syndrome in adult patients","volume":"296","author":"Pfister","year":"2006","journal-title":"Int J Med Microbiol"},{"key":"2025082701325520000_2018.mar29_2.bcr-2017-222976.5","doi-asserted-by":"crossref","first-page":"e5","DOI":"10.1016\/j.amjmed.2008.02.032","article-title":"Pseudotumor cerebri: early manifestation of adult Lyme disease","volume":"121","author":"Castaldo","year":"2008","journal-title":"Am J Med"},{"key":"2025082701325520000_2018.mar29_2.bcr-2017-222976.6","doi-asserted-by":"publisher","DOI":"10.1136\/bcr-2012-008060"},{"key":"2025082701325520000_2018.mar29_2.bcr-2017-222976.7","doi-asserted-by":"publisher","DOI":"10.1016\/S0887-8994(97)00215-4"},{"key":"2025082701325520000_2018.mar29_2.bcr-2017-222976.8","doi-asserted-by":"crossref","unstructured":"Nord JA , Karter D . 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