{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,29]],"date-time":"2026-06-29T06:11:38Z","timestamp":1782713498248,"version":"3.54.5"},"reference-count":45,"publisher":"BMJ","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Reports"],"accepted":{"date-parts":[[2018,3,27]]},"abstract":"<jats:p>Three young women, aged 18\u201324 years, presented to general practice with signs and symptoms of exertional rhabdomyolysis in 2016. All attended the same gym and had undertaken an intensive physical workout. Presenting symptoms were severe muscle pain and swelling, significantly reduced range of motion in affected muscles and, in two cases, dark-coloured urine. One case had presented to the out-of-hours service 4\u2009months previously with similar symptoms but rhabdomyolysis was not considered, although retrospective history taking suggests that was the likely diagnosis. All three women were admitted to hospital, treated with intravenous fluids and discharged between 1 and 6\u2009days later. All made a full recovery with no renal sequelae. The cases were questioned about potential risk factors, and the only commonality was unaccustomed strenuous exercise.<\/jats:p>","DOI":"10.1136\/bcr-2017-223022","type":"journal-article","created":{"date-parts":[[2018,4,21]],"date-time":"2018-04-21T10:05:17Z","timestamp":1524305117000},"page":"bcr-2017-223022","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":6,"title":["Cluster of exertional rhabdomyolysis in three young women"],"prefix":"10.1136","volume":"2018","author":[{"given":"Fiona","family":"Mitchell","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hazel J","family":"Henderson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Faith","family":"Gardner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2018,4,21]]},"reference":[{"key":"2025042703273507000_2018.apr21_1.bcr-2017-223022.1","first-page":"1","article-title":"Exertional and CrossFit-Induced Rhabdomyolysis","volume":"0","author":"Meyer","year":"2017","journal-title":"Clin J Sport Med"},{"key":"2025042703273507000_2018.apr21_1.bcr-2017-223022.2","doi-asserted-by":"crossref","first-page":"864","DOI":"10.1097\/PEC.0b013e3181f9dcd1","article-title":"Exertional rhabdomyolysis--when should we start worrying? Case reports and literature review","volume":"26","author":"George","year":"2010","journal-title":"Pediatr Emerg Care"},{"key":"2025042703273507000_2018.apr21_1.bcr-2017-223022.3","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1016\/j.rehab.2011.09.010","article-title":"Isolated exercise-induced rhabdomyolysis of brachialis and brachioradialis muscles: an atypical clinical case","volume":"54","author":"Have","year":"2011","journal-title":"Ann Phys Rehabil Med"},{"key":"2025042703273507000_2018.apr21_1.bcr-2017-223022.4","doi-asserted-by":"publisher","DOI":"10.1136\/bjsm.2004.013235"},{"key":"2025042703273507000_2018.apr21_1.bcr-2017-223022.5","doi-asserted-by":"crossref","first-page":"496","DOI":"10.1097\/JSM.0b013e318291d39e","article-title":"Exertional rhabdomyolysis in an acutely detrained athlete\/exercise physiology professor","volume":"23","author":"Pearcey","year":"2013","journal-title":"Clin J Sport Med"},{"key":"2025042703273507000_2018.apr21_1.bcr-2017-223022.6","doi-asserted-by":"publisher","DOI":"10.1249\/01.MSS.0000084428.51143.8C"},{"key":"2025042703273507000_2018.apr21_1.bcr-2017-223022.7","doi-asserted-by":"publisher","DOI":"10.1097\/00063110-200412000-00013"},{"key":"2025042703273507000_2018.apr21_1.bcr-2017-223022.8","doi-asserted-by":"publisher","DOI":"10.1249\/01.mss.0000183478.12106.04"},{"key":"2025042703273507000_2018.apr21_1.bcr-2017-223022.9","doi-asserted-by":"publisher","DOI":"10.1249\/JSR.0b013e318237bf8a"},{"key":"2025042703273507000_2018.apr21_1.bcr-2017-223022.10","doi-asserted-by":"publisher","DOI":"10.1213\/ane.0b013e3181a9d8d9"},{"key":"2025042703273507000_2018.apr21_1.bcr-2017-223022.11","doi-asserted-by":"publisher","DOI":"10.1002\/mus.21740"},{"key":"2025042703273507000_2018.apr21_1.bcr-2017-223022.12","doi-asserted-by":"publisher","DOI":"10.1097\/00063110-200106000-00015"},{"key":"2025042703273507000_2018.apr21_1.bcr-2017-223022.13","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1123\/jsr.16.3.244","article-title":"Dehydration, cramping, and exertional rhabdomyolysis: a case report with suggestions for recovery","volume":"16","author":"Cleary","year":"2007","journal-title":"J Sport Rehabil"},{"key":"2025042703273507000_2018.apr21_1.bcr-2017-223022.14","doi-asserted-by":"crossref","first-page":"3506","DOI":"10.1519\/JSC.0b013e318216302f","article-title":"Exertional rhabdomyolysis in an adolescent athlete during preseason conditioning: a perfect storm","volume":"25","author":"Cleary","year":"2011","journal-title":"J Strength Cond Res"},{"key":"2025042703273507000_2018.apr21_1.bcr-2017-223022.15","doi-asserted-by":"publisher","DOI":"10.1097\/JSM.0b013e31817dd506"},{"key":"2025042703273507000_2018.apr21_1.bcr-2017-223022.16","first-page":"26","article-title":"Exertional rhabdomyolysis in 8 division 1 female lacrosse athletes: a case series","volume":"11","author":"Register","year":"2006","journal-title":"Human kinetics"},{"key":"2025042703273507000_2018.apr21_1.bcr-2017-223022.17","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1093\/milmed\/166.3.275","article-title":"Diagnosing exertional rhabdomyolysis: a brief review and report of two cases","volume":"166","author":"Walsworth","year":"2001","journal-title":"Mil Med"},{"key":"2025042703273507000_2018.apr21_1.bcr-2017-223022.18","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.296.6625.826"},{"key":"2025042703273507000_2018.apr21_1.bcr-2017-223022.19","doi-asserted-by":"crossref","first-page":"8","DOI":"10.2174\/187152212799857655","article-title":"Hemolysis and Rhabdomyolysis after Marathon and Long Distance Running","volume":"12","author":"Aaseth","year":"2012","journal-title":"Immunol Endocr Metab Agents Med Chem"},{"key":"2025042703273507000_2018.apr21_1.bcr-2017-223022.20","doi-asserted-by":"crossref","first-page":"1532","DOI":"10.4045\/tidsskr.15.1207","article-title":"An increase in the number of admitted patients with exercise-induced rhabdomyolysis","volume":"136","author":"Aalborg","year":"2016","journal-title":"Tidsskr Nor Laegeforen"},{"key":"2025042703273507000_2018.apr21_1.bcr-2017-223022.21","doi-asserted-by":"publisher","DOI":"10.1136\/emj.2008.065524"},{"key":"2025042703273507000_2018.apr21_1.bcr-2017-223022.22","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1007\/s40279-017-0689-z","article-title":"Perspectives on Exertional Rhabdomyolysis","volume":"47","author":"Rawson","year":"2017","journal-title":"Sports Med"},{"key":"2025042703273507000_2018.apr21_1.bcr-2017-223022.23","unstructured":"Eley R . Explainer: What is rhabdomyolysis and what\u2019s its connection to Crossfit? 2017 https:\/\/medicine.uq.edu.au\/article\/2017\/04\/explainer-what-rhabdomyolysis-and-what%E2%80%99s-its-connection-crossfit."},{"key":"2025042703273507000_2018.apr21_1.bcr-2017-223022.24","first-page":"1","article-title":"Crossfit induced rhabdomyolysis","volume":"38","author":"Glassman","year":"2005","journal-title":"Crossfit Journal"},{"key":"2025042703273507000_2018.apr21_1.bcr-2017-223022.25","doi-asserted-by":"crossref","first-page":"604","DOI":"10.23736\/S0022-4707.16.06243-5","article-title":"Perceived demands and postexercise physical dysfunction in CrossFit\u00ae compared to an ACSM based training session","volume":"57","author":"Drum","year":"2017","journal-title":"J Sports Med Phys Fitness"},{"key":"2025042703273507000_2018.apr21_1.bcr-2017-223022.26","first-page":"38","article-title":"When exercise causes exertional rhabdomyolysis","volume":"28","author":"Furman","year":"2015","journal-title":"J Am Acad Physician Assist"},{"key":"2025042703273507000_2018.apr21_1.bcr-2017-223022.27","doi-asserted-by":"crossref","first-page":"951","DOI":"10.1097\/PHM.0b013e3181ae107f","article-title":"Rhabdomyolysis in a young vegetarian athlete","volume":"88","author":"Borrione","year":"2009","journal-title":"Am J Phys Med Rehabil"},{"key":"2025042703273507000_2018.apr21_1.bcr-2017-223022.28","article-title":"Heroin induced rhabdomyolysis and compartment syndrome: Early recognition to prevent mitigation of serious morbidity and mortality","volume":"27","author":"Brodsky","year":"2012","journal-title":"Journal of General Internal Medicine"},{"key":"2025042703273507000_2018.apr21_1.bcr-2017-223022.29","doi-asserted-by":"publisher","DOI":"10.7205\/MILMED.172.6.656"},{"key":"2025042703273507000_2018.apr21_1.bcr-2017-223022.30","doi-asserted-by":"crossref","first-page":"e1039","DOI":"10.7205\/MILMED-D-13-00133","article-title":"Hydroxycut weight loss dietary supplements: a contributing factor in the development of exertional rhabdomyolysis in three U.S. Army soldiers","volume":"178","author":"Carol","year":"2013","journal-title":"Mil Med"},{"key":"2025042703273507000_2018.apr21_1.bcr-2017-223022.31","doi-asserted-by":"crossref","first-page":"521.e3","DOI":"10.1016\/j.ajem.2007.09.003","article-title":"Rhabdomyolysis: a lesson on the perils of exercising and drinking","volume":"26","author":"Chawla","year":"2008","journal-title":"Am J Emerg Med"},{"key":"2025042703273507000_2018.apr21_1.bcr-2017-223022.32","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/j.hrtlng.2013.11.009","article-title":"Full recovery after severe serotonin syndrome, severe rhabdomyolysis, multi-organ failure and disseminated intravascular coagulopathy from MDMA","volume":"43","author":"Davies","year":"2014","journal-title":"Heart Lung"},{"key":"2025042703273507000_2018.apr21_1.bcr-2017-223022.33","first-page":"279","article-title":"Drug induced rhabdomyolysis: Spontaneous case reports","volume":"37","author":"Kakosova","year":"2015","journal-title":"International Journal of Clinical Pharmacy"},{"key":"2025042703273507000_2018.apr21_1.bcr-2017-223022.34","article-title":"Sport supplements: Are they safe? A case of rhabdomyolysis and atrial fibrillation in a 28 year old man","volume":"26","author":"Khir","year":"2011","journal-title":"Journal of General Internal Medicine"},{"key":"2025042703273507000_2018.apr21_1.bcr-2017-223022.35","doi-asserted-by":"publisher","DOI":"10.1249\/01.mss.0000227643.06478.c6"},{"key":"2025042703273507000_2018.apr21_1.bcr-2017-223022.36","doi-asserted-by":"crossref","first-page":"1042","DOI":"10.7205\/MILMED.173.10.1042","article-title":"Rhabdomyolysis associated with bupropion use as a smoking cessation adjunct: review of the literature","volume":"173","author":"Miladi","year":"2008","journal-title":"Mil Med"},{"key":"2025042703273507000_2018.apr21_1.bcr-2017-223022.37","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1519\/00126548-200702000-00001","article-title":"Identification of signs and symptoms of acute exertional rhabdomyolysis in athletes: a guide for the practitioner","volume":"29","author":"Brudvig","year":"2007","journal-title":"Strength and Conditioning Journal"},{"key":"2025042703273507000_2018.apr21_1.bcr-2017-223022.38","doi-asserted-by":"crossref","first-page":"602","DOI":"10.1111\/imj.13055","article-title":"Outcomes of exertional rhabdomyolysis following high-intensity resistance training","volume":"46","author":"Huynh","year":"2016","journal-title":"Intern Med J"},{"key":"2025042703273507000_2018.apr21_1.bcr-2017-223022.39","doi-asserted-by":"crossref","first-page":"201","DOI":"10.7205\/MILMED-D-14-00274","article-title":"Exertional rhabdomyolysis: a case series of 30 hospitalized patients","volume":"180","author":"Oh","year":"2015","journal-title":"Mil Med"},{"key":"2025042703273507000_2018.apr21_1.bcr-2017-223022.40","doi-asserted-by":"publisher","DOI":"10.1177\/0363546505281243"},{"key":"2025042703273507000_2018.apr21_1.bcr-2017-223022.41","first-page":"89","article-title":"Exercise-induced rhabdomyolysis","volume":"129","author":"Hutton","year":"2016","journal-title":"N Z Med J"},{"key":"2025042703273507000_2018.apr21_1.bcr-2017-223022.42","first-page":"U01","article-title":"Sports Induced Cardiac Arrest: A Case of Missed Rhabdomyolysis","volume":"9","author":"Gautam","year":"2015","journal-title":"J Clin Diagn Res"},{"key":"2025042703273507000_2018.apr21_1.bcr-2017-223022.43","first-page":"pp898","article-title":"Resistance exercise-induced rhabdomyolysis: Need for immediate intervention and proper counselling","volume":"45","author":"Khalil","year":"2016","journal-title":"Aust Fam Physician"},{"key":"2025042703273507000_2018.apr21_1.bcr-2017-223022.44","doi-asserted-by":"publisher","DOI":"10.1249\/JSR.0b013e31818f0317"},{"key":"2025042703273507000_2018.apr21_1.bcr-2017-223022.45","doi-asserted-by":"crossref","first-page":"406","DOI":"10.4085\/1062-6050-51.5.12","article-title":"Return to Play After Exertional Rhabdomyolysis","volume":"51","author":"Schleich","year":"2016","journal-title":"J Athl Train"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2017-223022","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,27]],"date-time":"2025-04-27T10:27:50Z","timestamp":1745749670000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2017-223022"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,4,21]]},"references-count":45,"alternative-id":["10.1136\/bcr-2017-223022"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2017-223022","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,4,21]]}}}