{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T20:32:59Z","timestamp":1791232379232,"version":"4.1.0"},"reference-count":15,"publisher":"BMJ","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Reports"],"accepted":{"date-parts":[[2018,3,22]]},"abstract":"<jats:p>Perianal fistulae are commonly seen clinical entity. Development of malignancy within a perianal fistula is rare. Even rarer is the development of mucinous adenocarcinoma in a chronic fistula-in-ano. Only a handful of such cases have been reported in the past. A case of mucinous adenocarcinoma arising in chronic perianal fistula in a 34-year-old woman is being described. She presented with complaints of perineal fullness, pain and recurrent pus discharge from perianal fistula for 4 years. On radiological workup, a large solid-cystic pelvic mass was seen in relation to the fistula. On MRI, the lesion was mimicking a large horseshoe abscess. Transrectal ultrasound-guided biopsy and subsequent histopathological examination confirmed the presence of mucinous adenocarcinoma with tumour cells immunopositive for CK7 and CK20.<\/jats:p>","DOI":"10.1136\/bcr-2017-223063","type":"journal-article","created":{"date-parts":[[2018,4,5]],"date-time":"2018-04-05T07:25:32Z","timestamp":1522913132000},"page":"bcr-2017-223063","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":12,"title":["Mucinous adenocarcinoma arising from chronic perianal fistula mimicking horseshoe abscess"],"prefix":"10.1136","volume":"2018","author":[{"given":"Surya Nandan","family":"Prasad","sequence":"first","affiliation":[{"name":"Department of Radiodiagnosis, SGPGIMS, Lucknow, Uttar Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdul","family":"Razik","sequence":"additional","affiliation":[{"name":"Department of Radiodiagnosis, All India Institute Of Medical Sciences, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Farhana","family":"Siddiqui","sequence":"additional","affiliation":[{"name":"Department of Pathology, Era\u2019s Medical College and Hospital, Lucknow, Uttar Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hira","family":"Lal","sequence":"additional","affiliation":[{"name":"Department of Radiodiagnosis, SGPGIMS, Lucknow, Uttar Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2018,4,5]]},"reference":[{"key":"2025082805301806000_2018.apr05_1.bcr-2017-223063.1","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1159\/000351830","article-title":"A case of perianal mucinous adenocarcinoma arising from an anorectal fistula successfully resected after preoperative radiotherapy","volume":"7","author":"Ohta","year":"2013","journal-title":"Case Rep Gastroenterol"},{"key":"2025082805301806000_2018.apr05_1.bcr-2017-223063.2","doi-asserted-by":"publisher","DOI":"10.4251\/wjgo.v2.i7.307"},{"key":"2025082805301806000_2018.apr05_1.bcr-2017-223063.3","doi-asserted-by":"publisher","DOI":"10.1007\/s00384-009-0657-7"},{"key":"2025082805301806000_2018.apr05_1.bcr-2017-223063.4","first-page":"286","article-title":"Mucinous adenocarcinoma arising in an anorectal fistula","volume":"45","author":"Venclauskas","year":"2009","journal-title":"Med Kaunas Lith"},{"key":"2025082805301806000_2018.apr05_1.bcr-2017-223063.5","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1007\/s10151-007-0348-8","article-title":"Mucinous adenocarcinoma derived from chronic perianal fistulas: report of a case and review of the literature","volume":"11","author":"Leal","year":"2007","journal-title":"Tech Coloproctol"},{"key":"2025082805301806000_2018.apr05_1.bcr-2017-223063.6","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1007\/s10151-007-0322-5","article-title":"Perianal mucinous adenocarcinoma arising from chronic anorectal fistulae: a review from a single institution","volume":"11","author":"Ong","year":"2007","journal-title":"Tech Coloproctol"},{"key":"2025082805301806000_2018.apr05_1.bcr-2017-223063.7","doi-asserted-by":"publisher","DOI":"10.1007\/s10151-006-0251-8"},{"key":"2025082805301806000_2018.apr05_1.bcr-2017-223063.8","doi-asserted-by":"crossref","first-page":"s138","DOI":"10.1007\/s10151-004-0136-7","article-title":"A case of mucinous adenocarcinoma arising in long-standing multiple perianal and presacral fistulas","volume":"8","author":"Papapolychroniadis","year":"2004","journal-title":"Tech Coloproctol"},{"key":"2025082805301806000_2018.apr05_1.bcr-2017-223063.9","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1159\/000068857","article-title":"A case of large mucinous adenocarcinoma arising in a long-standing fistula-in-ano","volume":"20","author":"Erhan","year":"2003","journal-title":"Dig Surg"},{"key":"2025082805301806000_2018.apr05_1.bcr-2017-223063.10","first-page":"843","article-title":"Clinics in diagnostic imaging (143). 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