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This approach failed to attenuate the disease, and so rituximab was initiated with subsequent clinical improvement, normalisation of urinary sediment and marked regression of proteinuria; renal function remained stable. The renal biopsy immunofluorescence was crucial for the diagnosis.<\/jats:p>","DOI":"10.1136\/bcr-2017-223198","type":"journal-article","created":{"date-parts":[[2018,5,3]],"date-time":"2018-05-03T02:41:51Z","timestamp":1525315311000},"page":"bcr-2017-223198","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":1,"title":["Proliferative glomerulonephritis with linear immunoglobulin deposition: is this atypical antiglomerular basement membrane disease?"],"prefix":"10.1136","volume":"2018","author":[{"given":"Ana Catarina","family":"Teixeira","sequence":"first","affiliation":[{"name":"Nephrology, Centro Hospitalar e Universitario de Coimbra, Coimbra, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Helena","family":"Pinto","sequence":"additional","affiliation":[{"name":"Nephrology, Centro Hospitalar e Universit\u00e1rio de Coimbra, Coimbra, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nuno","family":"Oliveira","sequence":"additional","affiliation":[{"name":"Nephrology, Centro Hospitalar e Universit\u00e1rio de Coimbra, Coimbra, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carol","family":"Marinho","sequence":"additional","affiliation":[{"name":"Pathology Department, Centro Hospitalar e Universitario de Coimbra EPE, Coimbra, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2018,5,2]]},"reference":[{"key":"2025082703543381000_2018.may02_1.bcr-2017-223198.1","doi-asserted-by":"publisher","DOI":"10.1016\/j.kint.2016.02.001"},{"key":"2025082703543381000_2018.may02_1.bcr-2017-223198.2","doi-asserted-by":"publisher","DOI":"10.1093\/ckj\/sfw068"},{"key":"2025082703543381000_2018.may02_1.bcr-2017-223198.3","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0910500"},{"key":"2025082703543381000_2018.may02_1.bcr-2017-223198.4","doi-asserted-by":"publisher","DOI":"10.1038\/sj.ki.5002525"},{"key":"2025082703543381000_2018.may02_1.bcr-2017-223198.5","doi-asserted-by":"publisher","DOI":"10.1053\/ajkd.2002.33385"},{"key":"2025082703543381000_2018.may02_1.bcr-2017-223198.6","doi-asserted-by":"publisher","DOI":"10.1053\/j.ajkd.2013.08.032"},{"key":"2025082703543381000_2018.may02_1.bcr-2017-223198.7","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1093\/ckj\/sfw048","article-title":"Frequently relapsing anti-glomerular basement membrane antibody disease with changing clinical phenotype and antibody characteristics over time","volume":"9","author":"Gu","year":"2016","journal-title":"Clin Kidney J"},{"key":"2025082703543381000_2018.may02_1.bcr-2017-223198.8","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1093\/ckj\/sfw038","article-title":"Multiple recurrences of anti-glomerular basement membrane disease with variable antibody detection: can the laboratory be trusted?","volume":"9","author":"Liu","year":"2016","journal-title":"Clin Kidney J"},{"key":"2025082703543381000_2018.may02_1.bcr-2017-223198.9","doi-asserted-by":"crossref","first-page":"750","DOI":"10.1016\/j.kint.2016.01.018","article-title":"Glomerular disease with idiopathic linear immunoglobulin deposition: a rose by any other name would be atypical","volume":"89","author":"Rosales","year":"2016","journal-title":"Kidney Int"},{"key":"2025082703543381000_2018.may02_1.bcr-2017-223198.10","unstructured":"Jennette C , D\u2019Agati V , Olson J , et al ; 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