{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T10:40:31Z","timestamp":1756377631731,"version":"3.44.0"},"reference-count":11,"publisher":"BMJ","funder":[{"name":"Wellcome Trust DBT\/India Alliance"}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Reports"],"accepted":{"date-parts":[[2018,1,3]]},"abstract":"<jats:p>Hydatid disease of long bone is a rare presentation. Chemotherapy and surgery constitute the standard treatment of choice. Non-union of a pathological fracture of femur particularly due to hydatid disease has been known to be resistant to treatment. These resistant cases require combination drug chemotherapy and excision of the lesion. Reconstruction of a large skeletal defect following resection of the lesion poses a challenge to the orthopaedic surgeons. We discuss the staged treatment of hydatid disease of shaft of femur with resection and cement spacer application followed by reconstruction using massive skeletal allograft under cover of combination drug chemotherapy.<\/jats:p>","DOI":"10.1136\/bcr-2017-223332","type":"journal-article","created":{"date-parts":[[2018,1,23]],"date-time":"2018-01-23T23:30:30Z","timestamp":1516750230000},"page":"bcr-2017-223332","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":4,"title":["Combination drug chemotherapy and massive skeletal allograft in the management of hydatid disease of femur"],"prefix":"10.1136","volume":"2018","author":[{"given":"Deepak","family":"Gautam","sequence":"first","affiliation":[{"name":"Department of Orthopaedics, All India Institute of Medical Sciences, New Delhi, Delhi, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rajesh","family":"Malhotra","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, All India Institute of Medical Sciences, New Delhi, Delhi, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Siddharth","family":"Dubey","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, All India Institute of Medical Sciences, New Delhi, Delhi, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2018,1,23]]},"reference":[{"key":"2025082803112957000_2018.jan23_1.bcr-2017-223332.1","unstructured":"Eckert J , Gemmell MA , Meslin FX , et al . 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