{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T16:00:17Z","timestamp":1792425617006,"version":"4.5.0"},"reference-count":9,"publisher":"BMJ","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Reports"],"accepted":{"date-parts":[[2018,2,6]]},"abstract":"<jats:p>Transarterial chemoembolisation (TACE) is commonly used for unresectable intermediate-stage hepatocellular carcinoma (HCC). TACE is usually well-tolerated. We report a case of a patient who presented with a gastrointestinal bleed from TACE. A 64-year-old man presented with chronic hepatitis C cirrhosis and multifocal bilobar HCC. He had previously undergone multiple TACE sessions, radiofrequency ablation and stereotactic body radiation therapy. In the evening of his TACE procedure, he developed abdominal pain and haematemesis. An oesophagogastroduodenoscopy (OGD) showed non-bleeding oesophageal varices and ulcerations in the stomach and duodenum, with pathology demonstrating mucosal necrosis. The patient recovered and was discharged on omeprazole. While TACE is considered safe with most patients only experiencing postembolisation syndrome, vascular complications have been reported. In our patient, OGD revealed ulcerations, with biopsies confirming ischaemic ulceration. The likely aetiology was seepage of the embolic particles into neighbouring arteries. Patients should be carefully selected for TACE and monitored post procedure.<\/jats:p>","DOI":"10.1136\/bcr-2017-223339","type":"journal-article","created":{"date-parts":[[2018,2,21]],"date-time":"2018-02-21T08:11:15Z","timestamp":1519200675000},"page":"bcr-2017-223339","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":8,"title":["Gastric and duodenal ischaemia after transarterial chemoembolisation for hepatocellular carcinoma: an unexpected but significant complication"],"prefix":"10.1136","volume":"2018","author":[{"given":"Sai Pavan","family":"Chintalapati","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, Division of Gastroenterology and Hepatology, University of Michigan, Ann Arbor, Michigan, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1239-9613","authenticated-orcid":false,"given":"Arpan","family":"Patel","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Division of Gastroenterology and Hepatology, University of Michigan, Ann Arbor, Michigan, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hari","family":"Conjeevaram","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Division of Gastroenterology and Hepatology, University of Michigan, Ann Arbor, Michigan, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2018,2,21]]},"reference":[{"key":"2025082802104292000_2018.feb21_1.bcr-2017-223339.1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.20933"},{"key":"2025082802104292000_2018.feb21_1.bcr-2017-223339.2","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1111\/j.1477-2574.2010.00183.x","article-title":"Nonoperative therapies for combined modality treatment of hepatocellular cancer: expert consensus statement","volume":"12","author":"Schwarz","year":"2010","journal-title":"HPB"},{"key":"2025082802104292000_2018.feb21_1.bcr-2017-223339.3","first-page":"79","article-title":"[Complications after TACE in HCC]","volume":"36","author":"Schneewei\u00df","year":"2015","journal-title":"Rofo"},{"key":"2025082802104292000_2018.feb21_1.bcr-2017-223339.4","doi-asserted-by":"publisher","DOI":"10.1007\/s00270-006-0062-3"},{"key":"2025082802104292000_2018.feb21_1.bcr-2017-223339.5","doi-asserted-by":"crossref","first-page":"1554","DOI":"10.3748\/wjg.v11.i10.1554","article-title":"Anatomic and technical skill factor of gastroduodenal complication in post-transarterial embolization for hepatocellular carcinoma: a retrospective study of 280 cases","volume":"11","author":"Leung","year":"2005","journal-title":"World J Gastroenterol"},{"key":"2025082802104292000_2018.feb21_1.bcr-2017-223339.6","first-page":"837","article-title":"Gastroduodenal lesions after transcatheter arterial chemo-embolization in patients with hepatocellular carcinoma","volume":"83","author":"Hirakawa","year":"1988","journal-title":"Am J Gastroenterol"},{"key":"2025082802104292000_2018.feb21_1.bcr-2017-223339.7","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1159\/000368075","article-title":"Spinal cord ischemia secondary to transcatheter arterial chemoembolization for hepatocellular carcinoma","volume":"8","author":"Bazine","year":"2014","journal-title":"Case Rep Gastroenterol"},{"key":"2025082802104292000_2018.feb21_1.bcr-2017-223339.8","doi-asserted-by":"crossref","first-page":"321","DOI":"10.3350\/cmh.2012.18.3.321","article-title":"A case of necrotizing pancreatitis subsequent to transcatheter arterial chemoembolization in a patient with hepatocellular carcinoma","volume":"18","author":"Bae","year":"2012","journal-title":"Clin Mol Hepatol"},{"key":"2025082802104292000_2018.feb21_1.bcr-2017-223339.9","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1055\/s-0031-1280675","article-title":"Hepatic arterial embolization complicated by acute cholecystitis","volume":"28","author":"Shah","year":"2011","journal-title":"Semin Intervent Radiol"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2017-223339","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T09:10:50Z","timestamp":1756372250000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2017-223339"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,2,21]]},"references-count":9,"alternative-id":["10.1136\/bcr-2017-223339"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2017-223339","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,2,21]]}}}