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In the absence of an identifiable cause for her respiratory failure, she was diagnosed with acute respiratory distress syndrome due to her psoriatic flare. Treatment with cyclosporine was initiated together with low-dose systemic corticosteroids, intravenous vitamin C and thiamine. The patient made a dramatic recovery being weaned to nasal cannulae within 24\u2009hours after the initiation of this treatment protocol and was discharged home a few days later.<\/jats:p>","DOI":"10.1136\/bcr-2017-223475","type":"journal-article","created":{"date-parts":[[2018,2,2]],"date-time":"2018-02-02T14:18:30Z","timestamp":1517581110000},"page":"bcr-2017-223475","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":7,"title":["ARDS complicating pustular psoriasis: treatment with low-dose corticosteroids, vitamin C and thiamine"],"prefix":"10.1136","volume":"2018","author":[{"given":"Paul Ellis","family":"Marik","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ashleigh","family":"Long","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2018,2,2]]},"reference":[{"key":"2025042702432682000_2018.feb02_1.bcr-2017-223475.1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1972.01620080037010"},{"key":"2025042702432682000_2018.feb02_1.bcr-2017-223475.2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2009.11.022"},{"key":"2025042702432682000_2018.feb02_1.bcr-2017-223475.3","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2012.5669"},{"key":"2025042702432682000_2018.feb02_1.bcr-2017-223475.4","doi-asserted-by":"crossref","first-page":"1229","DOI":"10.1016\/j.chest.2016.11.036","article-title":"Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study","volume":"151","author":"Marik","year":"2017","journal-title":"Chest"},{"key":"2025042702432682000_2018.feb02_1.bcr-2017-223475.5","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1590\/S0365-05962011000300026","article-title":"Acute respiratory distress syndrome as a complication of generalized pustular psoriasis","volume":"86","author":"Maehara","year":"2011","journal-title":"An Bras Dermatol"},{"key":"2025042702432682000_2018.feb02_1.bcr-2017-223475.6","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1684\/ejd.2011.1303","article-title":"Erythrodermic psoriasis complicated by acute respiratory distress syndrome","volume":"21","author":"Al-Niaimi","year":"2011","journal-title":"Eur J Dermatol"},{"key":"2025042702432682000_2018.feb02_1.bcr-2017-223475.7","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1991.tb14777.x"},{"key":"2025042702432682000_2018.feb02_1.bcr-2017-223475.8","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1111\/j.1365-2133.2004.05777.x","article-title":"Generalized pustular psoriasis complicated by acute respiratory distress syndrome","volume":"150","author":"Abou-Samra","year":"2004","journal-title":"Br J Dermatol"},{"key":"2025042702432682000_2018.feb02_1.bcr-2017-223475.9","doi-asserted-by":"crossref","first-page":"496","DOI":"10.1111\/j.1365-2133.2006.07364.x","article-title":"Generalized pustular psoriasis complicated by acute respiratory distress syndrome","volume":"155","author":"Griffiths","year":"2006","journal-title":"Br J Dermatol"},{"issue":"Suppl 1","key":"2025042702432682000_2018.feb02_1.bcr-2017-223475.10","doi-asserted-by":"crossref","first-page":"S67","DOI":"10.1007\/s00403-002-0374-3","article-title":"Animal models of psoriasis and pustular psoriasis","volume":"295 Suppl 1","author":"Mizutani","year":"2003","journal-title":"Arch Dermatol Res"},{"key":"2025042702432682000_2018.feb02_1.bcr-2017-223475.11","doi-asserted-by":"crossref","first-page":"954","DOI":"10.1016\/j.chest.2017.07.014","article-title":"Hydrocortisone and ascorbic acid synergistically prevent and repair lipopolysaccharide-induced pulmonary endothelial barrier dysfunction","volume":"152","author":"Barabutis","year":"2017","journal-title":"Chest"},{"key":"2025042702432682000_2018.feb02_1.bcr-2017-223475.12","doi-asserted-by":"crossref","first-page":"910","DOI":"10.1097\/CCM.0000000000002346","article-title":"Glucocorticosteroids as adjunctive therapy for acute respiratory distress syndrome and sepsis? 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