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Haematological tests revealed severe anaemia with pancytopenia, which prompted further investigations including a bone marrow biopsy confirming a diagnosis of multiple myeloma. Chemotherapy gradually caused resolution of the macular detachments at 8 months follow-up. This report illustrates that a high index of suspicion regarding systemic condition is required in certain cases presenting as diabetic macular oedema, but not responding to the conventional treatment.<\/jats:p>","DOI":"10.1136\/bcr-2017-223485","type":"journal-article","created":{"date-parts":[[2018,4,17]],"date-time":"2018-04-17T14:25:21Z","timestamp":1523975121000},"page":"bcr-2017-223485","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":2,"title":["Multiple myeloma masquerading as diabetic macular oedema"],"prefix":"10.1136","volume":"2018","author":[{"given":"Kavitha","family":"Rao","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hemanth","family":"Murthy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"NS","family":"Muralidhar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Padmaja Kumari","family":"Rani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2018,4,17]]},"reference":[{"key":"2025042703243666000_2018.apr17_1.bcr-2017-223485.1","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(00)00118-4"},{"key":"2025042703243666000_2018.apr17_1.bcr-2017-223485.2","first-page":"179","article-title":"IgM paraprotein in the subretinal fluid of a patient with recurrent retinal detachment and Waldenstr\u00f6m\u2019s macroglobulinaemia","volume":"42","author":"Berta","year":"1985","journal-title":"Acta Med Hung"},{"key":"2025042703243666000_2018.apr17_1.bcr-2017-223485.3","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.1983.01040020051008"},{"key":"2025042703243666000_2018.apr17_1.bcr-2017-223485.4","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0420.1995.tb00019.x"},{"key":"2025042703243666000_2018.apr17_1.bcr-2017-223485.5","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.39.4.233"},{"key":"2025042703243666000_2018.apr17_1.bcr-2017-223485.6","doi-asserted-by":"publisher","DOI":"10.1097\/00006982-199616060-00001"},{"key":"2025042703243666000_2018.apr17_1.bcr-2017-223485.7","first-page":"280","article-title":"Serous macular detachment in lymphoproliferative disorders","volume":"26","author":"Kumar","year":"1991","journal-title":"Can J Ophthalmol"},{"key":"2025042703243666000_2018.apr17_1.bcr-2017-223485.8","first-page":"911","article-title":"Serous macular detachments in a patient with IgM paraproteinemia: an optical coherence tomography study","volume":"119","author":"Leys","year":"2001","journal-title":"Arch Ophthalmol"},{"key":"2025042703243666000_2018.apr17_1.bcr-2017-223485.9","doi-asserted-by":"crossref","first-page":"248","DOI":"10.3928\/1542-8877-20000501-19","article-title":"Occult retinal pigment epithelial detachment in hyperviscosity syndrome","volume":"31","author":"Ogata","year":"2000","journal-title":"Ophthalmic Surg Lasers"},{"key":"2025042703243666000_2018.apr17_1.bcr-2017-223485.10","doi-asserted-by":"publisher","DOI":"10.1007\/s10384-006-0428-8"},{"key":"2025042703243666000_2018.apr17_1.bcr-2017-223485.11","doi-asserted-by":"publisher","DOI":"10.1136\/pgmj.2008.071886"},{"key":"2025042703243666000_2018.apr17_1.bcr-2017-223485.12","doi-asserted-by":"crossref","unstructured":"Balderman SR , Lichtman MA . 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