{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,23]],"date-time":"2025-09-23T12:37:14Z","timestamp":1758631034660,"version":"3.44.0"},"reference-count":8,"publisher":"BMJ","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Reports"],"accepted":{"date-parts":[[2018,3,27]]},"abstract":"<jats:p>Hyperkalaemic periodic paralysis is a rare skeletal muscle disorder which is characterised by episodic muscle paralysis associated with hyperkalaemia. Although it is an autosomal-dominant disease, cases of de novo mutations have been reported. We report the case of a 30-year-old woman, gravida 5 para 3+1, who was planned for an elective repeated caesarean section at 38 weeks and 3 days of pregnancy. She developed recurrent episodes of hyperkalaemic periodic paralysis after receiving corticosteroids. Intravenous calcium gluconate was administered to normalise potassium levels (from 6.3\u2009mmol\/L to 4.1\u2009mmol\/L). Extra anaesthetic precautions were taken during the caesarean delivery. Postoperatively, she was well and discharged from the ward. She encountered similar symptoms in her third pregnancy, and there was no family history of muscle weakness which suggested a de novo mutation. Pregnancy seemed to result in vulnerability to hyperkalaemic attacks as she was never symptomatic outside pregnancy.<\/jats:p>","DOI":"10.1136\/bcr-2017-223588","type":"journal-article","created":{"date-parts":[[2018,6,4]],"date-time":"2018-06-04T03:30:22Z","timestamp":1528083022000},"page":"bcr-2017-223588","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":3,"title":["Hyperkalaemic periodic paralysis in pregnancy"],"prefix":"10.1136","volume":"2018","author":[{"given":"Soon-Leong","family":"Yong","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynaecology, Sibu Hospital, Sibu, Sarawak, Malaysia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Teik-Hoy","family":"Sin","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology, Sibu Hospital, Sibu, Sarawak, Malaysia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eric Boon-Kiat","family":"Tang","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, SEGi University Sibu Clinical Campus, Sibu, Sarawak, Malaysia"},{"name":"Department of Anaesthesiology, Sibu Hospital, Sibu, Sarawak, Malaysia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ming-Cheng","family":"Chai","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology, Sarikei Hospital, Sarikei, Sarawak, Malaysia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2018,6,4]]},"reference":[{"key":"2025082707424284000_2018.jun01_1.bcr-2017-223588.1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0b013e31828cf8d0"},{"key":"2025082707424284000_2018.jun01_1.bcr-2017-223588.2","unstructured":"Weber F , Jurkat-Rott K , Lehmann-Horn F , et al . Hyperkalemic Periodic Paralysis. In: Pagon RA , Adam MP , Ardinger HH , GeneReviews. Seattle (WA: University of Washington, Seattle, 1993."},{"key":"2025082707424284000_2018.jun01_1.bcr-2017-223588.3","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-013-7025-9"},{"key":"2025082707424284000_2018.jun01_1.bcr-2017-223588.4","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0404.2007.00963.x"},{"key":"2025082707424284000_2018.jun01_1.bcr-2017-223588.5","first-page":"832","article-title":"Gamstorp\u2019s disease and pregnancy. A case report","volume":"25","author":"Therby","year":"1996","journal-title":"J Gynecol Obstet Biol Reprod"},{"key":"2025082707424284000_2018.jun01_1.bcr-2017-223588.6","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1097\/NRL.0b013e31818fc765","article-title":"Disappearance of episodic weakness during pregnancy in hyperkalemic periodic paralysis from the SCNA4 mutation T704M","volume":"15","author":"Finsterer","year":"2009","journal-title":"Neurologist"},{"key":"2025082707424284000_2018.jun01_1.bcr-2017-223588.7","doi-asserted-by":"crossref","first-page":"75","DOI":"10.4103\/0972-2327.194312","article-title":"Pregnancy reduces severity and frequency of attacks in hyperkalemic periodic paralysis due to the mutation c.2111C>T in theSCN4Agene","volume":"20","author":"Finsterer","year":"2017","journal-title":"Ann Indian Acad Neurol"},{"key":"2025082707424284000_2018.jun01_1.bcr-2017-223588.8","unstructured":"Lehmann-Horn F , Rudel R , Jurkat-Rott K . Non-dystrophic myotonias and periodic paralyses. In: Engel AG , Franzini-Armstrong C , eds. Myology: Basic and Clinical. 3 ed. New York, NY: \u00a0McGraw-Hill, 2004:1257\u2013300."}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2017-223588","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T14:42:48Z","timestamp":1756305768000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2017-223588"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,6,4]]},"references-count":8,"alternative-id":["10.1136\/bcr-2017-223588"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2017-223588","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2018,6,4]]}}}