{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,22]],"date-time":"2026-07-22T11:36:55Z","timestamp":1784720215788,"version":"3.55.0"},"reference-count":12,"publisher":"BMJ","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Reports"],"accepted":{"date-parts":[[2018,5,7]]},"abstract":"<jats:p>We present the case of a 49-year-old man with a bicuspid aortic valve who presented to the emergency department with limb weakness and a fever. Blood tests revealed a fulminant septic process with <jats:italic>Haemophilus parainfluenzae<\/jats:italic> bacteraemia, anaemia and thrombocytopenia. Imaging revealed a cervical spinal abscess and discitis causing spinal cord compression, in addition to multiple cerebral septic emboli, pleural effusions and ascites. A transoesophageal echocardiogram (TOE) performed post decompression of his spinal collection showed native aortic valve endocarditis with an associated large aortic root abscess. He underwent successful aortic valve surgery and a 6-week course of antibiotic therapy and made an excellent clinical recovery with no long-term complications from his condition.<\/jats:p>","DOI":"10.1136\/bcr-2017-223775","type":"journal-article","created":{"date-parts":[[2018,6,4]],"date-time":"2018-06-04T08:49:12Z","timestamp":1528102152000},"page":"bcr-2017-223775","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":5,"title":["An aggressive form of <i>Haemophilus parainfluenzae<\/i> infective endocarditis presenting with limb weakness"],"prefix":"10.1136","volume":"2018","author":[{"given":"Naina","family":"McCann","sequence":"first","affiliation":[{"name":"Department of Infectious Diseases, University College London Hospital, London, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohamad Fahed","family":"Barakat","sequence":"additional","affiliation":[{"name":"School of Cardiovascular Medicine & Sciences, King\u2019s College London, London, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frank","family":"Schafer","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Royal Free London NHS Foundation Trust, London, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2018,6,4]]},"reference":[{"key":"2025082802154040000_2018.jun01_1.bcr-2017-223775.1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ahj.2012.04.003"},{"key":"2025082802154040000_2018.jun01_1.bcr-2017-223775.2","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.160.18.2781"},{"key":"2025082802154040000_2018.jun01_1.bcr-2017-223775.3","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.med.48.1.25"},{"key":"2025082802154040000_2018.jun01_1.bcr-2017-223775.4","doi-asserted-by":"publisher","DOI":"10.1086\/513624"},{"key":"2025082802154040000_2018.jun01_1.bcr-2017-223775.5","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1097\/00005792-197703000-00003","article-title":"Haemophilus parainfluenzae and influenzae endocarditis: a review of forty cases","volume":"56","author":"Lynn","year":"1977","journal-title":"Medicine"},{"key":"2025082802154040000_2018.jun01_1.bcr-2017-223775.6","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.14.1.177-207.2001"},{"key":"2025082802154040000_2018.jun01_1.bcr-2017-223775.7","doi-asserted-by":"crossref","first-page":"71","DOI":"10.14740\/jocmr2703w","article-title":"Ischemic stroke and septic shock after subacute endocarditis caused by haemophilus parainfluenzae: case report","volume":"9","author":"Menegueti","year":"2017","journal-title":"J Clin Med Res"},{"key":"2025082802154040000_2018.jun01_1.bcr-2017-223775.8","doi-asserted-by":"publisher","DOI":"10.1136\/bcr-2016-216473"},{"key":"2025082802154040000_2018.jun01_1.bcr-2017-223775.9","first-page":"119","article-title":"Bacterial endocarditis revealed by infectious discitis","volume":"63","author":"Pascaretti","year":"1996","journal-title":"Rev Rhum Engl Ed"},{"key":"2025082802154040000_2018.jun01_1.bcr-2017-223775.10","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.54.1.140"},{"key":"2025082802154040000_2018.jun01_1.bcr-2017-223775.11","doi-asserted-by":"publisher","DOI":"10.1086\/510583"},{"key":"2025082802154040000_2018.jun01_1.bcr-2017-223775.12","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(83)90203-5"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2017-223775","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T09:15:48Z","timestamp":1756372548000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2017-223775"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,6,4]]},"references-count":12,"alternative-id":["10.1136\/bcr-2017-223775"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2017-223775","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,6,4]]}}}