{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T09:40:05Z","timestamp":1756374005662,"version":"3.44.0"},"reference-count":9,"publisher":"BMJ","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Reports"],"accepted":{"date-parts":[[2018,4,7]]},"abstract":"<jats:p>Isolated hypoglossal nerve palsy is uncommon because of its intimate relationship with the other lower cranial nerves. Keane reported that tumours, predominantly malignant, were the most common cause of hypoglossal nerve palsy. We report a case of isolated idiopathic unilateral hypoglossal nerve palsy in a 45-year-old Caucasian male where no cause could be identified despite extensive investigations. There was uncertainty around prognosis at onset due to the rarity of this condition. In the absence of a cause, an early referral to the speech and language therapist was made and interestingly our patient made an almost complete recovery within 18 months of onset. In a small case series, it has been reported that though rare, idiopathic hypoglossal nerve palsy has an excellent outcome in most cases, similar to the more common idiopathic seventh cranial nerve palsy (Bell\u2019s Palsy).We recommend an early referral for physiotherapy in such cases.<\/jats:p>","DOI":"10.1136\/bcr-2017-223968","type":"journal-article","created":{"date-parts":[[2018,5,4]],"date-time":"2018-05-04T06:10:30Z","timestamp":1525414230000},"page":"bcr-2017-223968","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":1,"title":["Case of idiopathic isolated unilateral hypoglossal nerve palsy with spontaneous recovery"],"prefix":"10.1136","volume":"2018","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7572-1644","authenticated-orcid":false,"given":"Binay","family":"Gurung","sequence":"first","affiliation":[{"name":"Leicester Medical School, University of Leicester, Leicester, UK"},{"name":"Department of Medicine, Burton Hospitals NHS Foundation Trust, Burton-on-Trent, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ismail Ahmad","family":"Chaudhry","sequence":"additional","affiliation":[{"name":"Leicester Medical School, University of Leicester, Leicester, UK"},{"name":"Department of Medicine, Burton Hospitals NHS Foundation Trust, Burton-on-Trent, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nawazish","family":"Karim","sequence":"additional","affiliation":[{"name":"Department of Medicine, Burton Hospitals NHS Foundation Trust, Burton-on-Trent, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Uttam","family":"Nanda","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine, Burton Hospitals NHS Foundation Trusts, Burton-on-Trent, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2018,5,4]]},"reference":[{"key":"2025082802014686000_2018.may03_1.bcr-2017-223968.1","doi-asserted-by":"publisher","DOI":"10.1007\/s003300050492"},{"key":"2025082802014686000_2018.may03_1.bcr-2017-223968.2","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1996.00550060105023"},{"key":"2025082802014686000_2018.may03_1.bcr-2017-223968.3","doi-asserted-by":"crossref","first-page":"803","DOI":"10.1017\/S0022215107006275","article-title":"Isolated hypoglossal nerve palsy: a harbinger of malignancy","volume":"121","author":"Khoo","year":"2007","journal-title":"J Laryngol Otol"},{"key":"2025082802014686000_2018.may03_1.bcr-2017-223968.4","doi-asserted-by":"publisher","DOI":"10.1007\/s004150050185"},{"key":"2025082802014686000_2018.may03_1.bcr-2017-223968.5","doi-asserted-by":"publisher","DOI":"10.1159\/000104720"},{"key":"2025082802014686000_2018.may03_1.bcr-2017-223968.6","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejrad.2009.08.028"},{"key":"2025082802014686000_2018.may03_1.bcr-2017-223968.7","unstructured":"Sharma B , Dubey P , Kumar S , et al . Isolated unilateral hypoglossal nerve palsy: a study of 12 cases. J Neurol Neurosci 2011;2."},{"key":"2025082802014686000_2018.may03_1.bcr-2017-223968.8","doi-asserted-by":"publisher","DOI":"10.1159\/000057906"},{"key":"2025082802014686000_2018.may03_1.bcr-2017-223968.9","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1213\/ANE.0000000000000495","article-title":"Hypoglossal nerve palsy after airway management for general anesthesia: an analysis of 69 patients","volume":"120","author":"Shah","year":"2015","journal-title":"Anesth Analg"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2017-223968","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T09:01:53Z","timestamp":1756371713000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2017-223968"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,5,4]]},"references-count":9,"alternative-id":["10.1136\/bcr-2017-223968"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2017-223968","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2018,5,4]]}}}