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Molecular genetic analysis by fluorescence in situ hybridisation was performed which showed translocation of 22q12, thereby confirming the diagnosis. This is a rare secondary malignancy and an unusual association. This case highlights the importance and diagnostic dilemmas of rare secondary tumours in patients with such haematological malignancies and discusses its possible pathogenetic aspects.<\/jats:p>","DOI":"10.1136\/bcr-2017-224071","type":"journal-article","created":{"date-parts":[[2018,6,12]],"date-time":"2018-06-12T01:05:22Z","timestamp":1528765522000},"page":"bcr-2017-224071","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":1,"title":["Metachronous renal Ewing sarcoma\/primitive neuroectodermal tumour in a survivor of Burkitt lymphoma"],"prefix":"10.1136","volume":"2018","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1730-8947","authenticated-orcid":false,"given":"Kumail","family":"Khandwala","sequence":"first","affiliation":[{"name":"Department of Radiology, Aga Khan University, Karachi, Pakistan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kiran","family":"Hilal","sequence":"additional","affiliation":[{"name":"Department of Radiology, Aga Khan University, Karachi, Pakistan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zehra","family":"Fadoo","sequence":"additional","affiliation":[{"name":"Department of Haematology and Oncology, Aga Khan University, Karachi, Pakistan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Khurram","family":"Minhas","sequence":"additional","affiliation":[{"name":"Department of Pathology and Laboratory Medicine, Aga Khan University, Karachi, Pakistan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2018,6,11]]},"reference":[{"key":"2025082702435170000_2018.jun11_1.bcr-2017-224071.1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1155\/2016\/5043640","article-title":"Ewing\u2019s Sarcoma as a second malignancy in long-term survivors of childhood hematologic malignancies","volume":"2016","author":"Wolpert","year":"2016","journal-title":"Sarcoma"},{"key":"2025082702435170000_2018.jun11_1.bcr-2017-224071.2","doi-asserted-by":"crossref","first-page":"396","DOI":"10.3109\/0284186X.2015.1054951","article-title":"Second primary malignancy in Burkitt\u2019s lymphoma","volume":"55","author":"Shah","year":"2016","journal-title":"Acta Oncol"},{"key":"2025082702435170000_2018.jun11_1.bcr-2017-224071.3","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.28991"},{"key":"2025082702435170000_2018.jun11_1.bcr-2017-224071.4","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1002\/mpo.2950220504","article-title":"Second primary neoplasms in a population-based series of patients diagnosed with renal tumours in childhood","volume":"22","author":"Hartley","year":"1994","journal-title":"Med Pediatr Oncol"},{"key":"2025082702435170000_2018.jun11_1.bcr-2017-224071.5","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.21971"},{"key":"2025082702435170000_2018.jun11_1.bcr-2017-224071.6","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.21962"},{"key":"2025082702435170000_2018.jun11_1.bcr-2017-224071.7","doi-asserted-by":"publisher","DOI":"10.1016\/S0165-4608(95)00014-3"},{"key":"2025082702435170000_2018.jun11_1.bcr-2017-224071.8","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.20159"},{"key":"2025082702435170000_2018.jun11_1.bcr-2017-224071.9","doi-asserted-by":"publisher","DOI":"10.1097\/00043426-199502000-00014"},{"key":"2025082702435170000_2018.jun11_1.bcr-2017-224071.10","doi-asserted-by":"publisher","DOI":"10.1093\/jjco\/hyt047"},{"key":"2025082702435170000_2018.jun11_1.bcr-2017-224071.11","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1155\/2014\/283902","article-title":"Ewing sarcoma of the kidney: a rare entity","volume":"2014","author":"Almeida","year":"2014","journal-title":"Case Rep Radiol"},{"key":"2025082702435170000_2018.jun11_1.bcr-2017-224071.12","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-200203000-00005"},{"key":"2025082702435170000_2018.jun11_1.bcr-2017-224071.13","doi-asserted-by":"crossref","first-page":"E156","DOI":"10.1002\/dc.21717","article-title":"Primary Ewing\u2019s sarcoma\/primitive neuroectodermal tumor of the kidney: Report of a case diagnosed by fine needle aspiration cytology and confirmed by immunocytochemistry and RT-PCR along with review of literature","volume":"40","author":"Kumar","year":"2012","journal-title":"Diagn Cytopathol"},{"key":"2025082702435170000_2018.jun11_1.bcr-2017-224071.14","unstructured":"de Alava E , Lessnik LS , Sorensen PH , et al . In: Fletcher CDM, Bridge JA, Hogendoorn PCW, Mertens F, editors. WHO Classification of Tumours of Soft Tissue and Bone. 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