{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T04:00:14Z","timestamp":1785556814138,"version":"3.56.0"},"reference-count":12,"publisher":"BMJ","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Reports"],"accepted":{"date-parts":[[2018,4,26]]},"abstract":"<jats:p>A 13-year-old boy with neurofibromatosis type 1 presented to the emergency department twice in a fortnight with moderate intermittent abdominal pain, radiating to the back and associated with nausea and vomiting. He examined as a well child with a soft abdomen and minimal tenderness. A history of constipation was identified but he failed to respond to a trial of laxatives. Subsequent ultrasound abdomen demonstrated a large mass surrounding the porta hepatis. MRI further characterised a focal, non-aggressive lesion extending from his liver, encapsulating his pancreas, portal vessels and laterally displacing his spleen and left kidney. Biopsy performed at a specialist cancer treatment hospital of our reference later confirmed this to be a benign neurofibroma of a size not previously reported in the literature. He will be managed conservatively with surveillance imaging and the potential for chemotherapy should the lesion continue to grow.<\/jats:p>","DOI":"10.1136\/bcr-2018-224174","type":"journal-article","created":{"date-parts":[[2018,5,15]],"date-time":"2018-05-15T02:25:14Z","timestamp":1526351114000},"page":"bcr-2018-224174","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":1,"title":["Not so mass effect? Finding of a remarkable \u2018incidentaloma\u2019 in a teenager with neurofibromatosis"],"prefix":"10.1136","volume":"2018","author":[{"given":"Daniel John","family":"Keen","sequence":"first","affiliation":[{"name":"Department of Paediatrics, East Sussex Healthcare NHS Trust, Saint Leonards-on-Sea, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hannah","family":"Norman-Bruce","sequence":"additional","affiliation":[{"name":"Department of Paediatrics, East Sussex Healthcare NHS Trust, Saint Leonards-on-Sea, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Salah","family":"Mansy","sequence":"additional","affiliation":[{"name":"Department of Paediatrics, East Sussex Healthcare NHS Trust, Saint Leonards-on-Sea, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2018,5,14]]},"reference":[{"key":"2025082804494727000_2018.may14_1.bcr-2018-224174.1","doi-asserted-by":"crossref","unstructured":"Gerber PM , Antal AS , Neumann NJ , et al . Neurofibromatosis. European Journal of Medical Research 2009;14.","DOI":"10.1186\/2047-783X-14-3-102"},{"key":"2025082804494727000_2018.may14_1.bcr-2018-224174.2","unstructured":"U.S\u00a0National Library of Medicine. Neurofibromatosis type. 2017. https:\/\/ghr.nlm.nih.gov\/condition\/neurofibromatosis-type-1#sourcesforpage (accessed 26 Jun 2017)."},{"key":"2025082804494727000_2018.may14_1.bcr-2018-224174.3","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.pathol.2.010506.091940"},{"key":"2025082804494727000_2018.may14_1.bcr-2018-224174.4","doi-asserted-by":"crossref","first-page":"e280","DOI":"10.1016\/j.crad.2014.01.020","article-title":"MRI features of plexiform neurofibromas involving the liver and pancreas in children with neurofibromatosis type 1","volume":"69","author":"Delgado","year":"2014","journal-title":"Clin Radiol"},{"key":"2025082804494727000_2018.may14_1.bcr-2018-224174.5","doi-asserted-by":"crossref","first-page":"005","DOI":"10.1055\/s-0033-1345105","article-title":"Diagnosis and management of an isolated pediatric plexiform neurofibroma involving the hepatic and celiac plexus using multimodality approach: problem solving with diffusion-weighted magnetic resonance imaging","volume":"1","author":"Scheurkogel","year":"2013","journal-title":"European J Pediatr Surg Rep"},{"key":"2025082804494727000_2018.may14_1.bcr-2018-224174.6","first-page":"363","article-title":"Massive plexiform neurofibromas in childhood: natural history and management issues","volume":"106","author":"Serletis","year":"2007","journal-title":"J Neurosurg"},{"key":"2025082804494727000_2018.may14_1.bcr-2018-224174.7","doi-asserted-by":"publisher","DOI":"10.1007\/s002470100493"},{"key":"2025082804494727000_2018.may14_1.bcr-2018-224174.8","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1111\/ped.13455","article-title":"Intrahepatic plexiform neurofibroma with neurofibromatosis type 1","volume":"60","author":"Kusama","year":"2018","journal-title":"Pediatr Int"},{"key":"2025082804494727000_2018.may14_1.bcr-2018-224174.9","doi-asserted-by":"crossref","first-page":"578","DOI":"10.1016\/j.dld.2007.12.013","article-title":"Intestinal plexiform neurofibromas","volume":"40","author":"Calligaris","year":"2008","journal-title":"Dig Liver Dis"},{"key":"2025082804494727000_2018.may14_1.bcr-2018-224174.10","first-page":"13","article-title":"Abdominal pain: a unique presentation of neurofibromatosis and updated review of the condition","volume":"36","author":"Nickle","year":"2016","journal-title":"J Am Osteopathic College Dermatol"},{"key":"2025082804494727000_2018.may14_1.bcr-2018-224174.11","first-page":"1","article-title":"Neurofibromatosis type 1 presenting with plexiform neurofibromas in two patients: MRI features","volume":"2012","author":"Halefoglu","year":"2012","journal-title":"Case Rep Med"},{"key":"2025082804494727000_2018.may14_1.bcr-2018-224174.12","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1605943"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2018-224174","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T11:49:55Z","timestamp":1756381795000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2018-224174"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,5,14]]},"references-count":12,"alternative-id":["10.1136\/bcr-2018-224174"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2018-224174","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,5,14]]}}}