{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,22]],"date-time":"2026-06-22T15:56:49Z","timestamp":1782143809134,"version":"3.54.5"},"reference-count":9,"publisher":"BMJ","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Reports"],"accepted":{"date-parts":[[2018,2,28]]},"abstract":"<jats:p>A 33-year-old man presented with a 10-day history of bilateral blurred vision on a background of a prodromal influenza-like illness. Ocular Coherence Tomography (OCT) and fundal examination coincided with a diagnosis of atypical central serous retinopathy. The patient\u2019s symptoms worsened during follow-up, and he was started on steroids. Subsequent fundal examination revealed yellow deposits in a honeycomb pattern and hard exudates in the perimacular region. Serial OCTs revealed progression of bilateral macular intraretinal and subretinal fluid. He was subsequently admitted to hospital for a full paraneoplastic workup. Liaison with our colleagues in other specialist retinal centres led us to a diagnosis of acute exudative polymorphous vitelliform maculopathy syndrome. We subsequently took fundal images to monitor disease progression and to monitor changes seen with autofluorescence in this rare disease entity.<\/jats:p>","DOI":"10.1136\/bcr-2018-224241","type":"journal-article","created":{"date-parts":[[2018,3,20]],"date-time":"2018-03-20T13:38:32Z","timestamp":1521553112000},"page":"bcr-2018-224241","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":3,"title":["Acute Exudative Polymorphous Vitelliform Maculopathy Syndrome; natural history and evolution of fundal and OCT images over time"],"prefix":"10.1136","volume":"2018","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1892-459X","authenticated-orcid":false,"given":"Patrick","family":"Murtagh","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maxwell","family":"Treacy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kirk","family":"Stephenson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ian","family":"Dooley","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2018,3,20]]},"reference":[{"key":"2025042703093131000_2018.mar20_1.bcr-2018-224241.1","first-page":"354","article-title":"Acute exudative polymorphous vitelliform maculopathy","volume":"86","author":"Gass","year":"1988","journal-title":"Trans Am Ophthalmol Soc"},{"key":"2025042703093131000_2018.mar20_1.bcr-2018-224241.2","doi-asserted-by":"crossref","first-page":"91","DOI":"10.5301\/ejo.5000616","article-title":"A case of acute exudative polymorphous vitelliform maculopathy: follow-up and wide-field spectral-domain optical coherence tomography","volume":"25","author":"Massaro","year":"2015","journal-title":"Eur J Ophthalmol"},{"key":"2025042703093131000_2018.mar20_1.bcr-2018-224241.3","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/j.ophtha.2017.07.020","article-title":"Idiopathic Acute Exudative Polymorphous Vitelliform Maculopathy: Clinical Spectrum and Multimodal Imaging Characteristics","volume":"125","author":"Barbazetto","year":"2018","journal-title":"Ophthalmology"},{"key":"2025042703093131000_2018.mar20_1.bcr-2018-224241.4","doi-asserted-by":"publisher","DOI":"10.1001\/archophthalmol.2011.215"},{"key":"2025042703093131000_2018.mar20_1.bcr-2018-224241.5","doi-asserted-by":"publisher","DOI":"10.1097\/00006982-200308000-00002"},{"key":"2025042703093131000_2018.mar20_1.bcr-2018-224241.6","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(95)30960-8"},{"key":"2025042703093131000_2018.mar20_1.bcr-2018-224241.7","doi-asserted-by":"publisher","DOI":"10.1097\/00006982-200308000-00002"},{"key":"2025042703093131000_2018.mar20_1.bcr-2018-224241.8","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1007\/s00417-013-2563-5","article-title":"Ocular diseases in metastatic cutaneous melanoma: review of 108 consecutive patients in two German tertiary centers","volume":"252","author":"Grajewski","year":"2014","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"key":"2025042703093131000_2018.mar20_1.bcr-2018-224241.9","doi-asserted-by":"publisher","DOI":"10.1001\/archophthalmol.2010.316"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2018-224241","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,27]],"date-time":"2025-04-27T10:09:41Z","timestamp":1745748581000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2018-224241"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,3,20]]},"references-count":9,"alternative-id":["10.1136\/bcr-2018-224241"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2018-224241","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,3,20]]}}}