{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,28]],"date-time":"2025-04-28T04:01:32Z","timestamp":1745812892822,"version":"3.40.4"},"reference-count":7,"publisher":"BMJ","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Reports"],"accepted":{"date-parts":[[2018,4,11]]},"abstract":"<jats:p>Q fever is a zoonotic disease caused by<jats:italic>Coxiella burnetii<\/jats:italic>that usually presents with non-specific or benign constitutional symptoms. Diagnosis is often challenging and, after acute Q fever, 1%\u20135% of patients can develop chronic disease. We present an 80-year-old male patient who was admitted due to a 3\u2009months history of fever, productive cough, myalgia, weight loss, headache and hearing loss. Chronic Q fever was confirmed by positive antiphase I immunoglobulin G. Frequent locations of chronic infection was discarded, and ear CT revealed a right mastoid infection. He was treated with doxycycline and hydroxychloroquine for 18 months with significant improvement. This is a rare case of chronic Q fever presenting with otomastoiditis that has never been described.<\/jats:p>","DOI":"10.1136\/bcr-2018-224315","type":"journal-article","created":{"date-parts":[[2018,4,21]],"date-time":"2018-04-21T10:05:14Z","timestamp":1524305114000},"page":"bcr-2018-224315","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":1,"title":["Rare case of otomastoiditis due to<i>Coxiella burnetii<\/i>chronic infection"],"prefix":"10.1136","volume":"2018","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7905-6976","authenticated-orcid":false,"given":"Mariana","family":"Gon\u00e7alves","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3363-0589","authenticated-orcid":false,"given":"S\u00f3nia","family":"Moreira","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elsa","family":"Gaspar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L\u00e8lita","family":"Santos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2018,4,21]]},"reference":[{"key":"2025042703273064000_2018.apr21_1.bcr-2018-224315.1","first-page":"1","article-title":"Diagnosis and management of Q fever \u2013 United States, 2013: recommendations from CDC and the Q Fever Working Group","volume":"62","author":"Anderson","year":"2013","journal-title":"MMWR Recomm Rep"},{"key":"2025042703273064000_2018.apr21_1.bcr-2018-224315.2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.1990.tb42204.x"},{"key":"2025042703273064000_2018.apr21_1.bcr-2018-224315.3","doi-asserted-by":"publisher","DOI":"10.1097\/00005792-200003000-00005"},{"key":"2025042703273064000_2018.apr21_1.bcr-2018-224315.4","doi-asserted-by":"crossref","first-page":"972","DOI":"10.1097\/INF.0000000000001211","article-title":"Chronic recurrent multifocal Q fever osteomyelitis in children: an emerging clinical challenge","volume":"35","author":"Francis","year":"2016","journal-title":"Pediatr Infect Dis J"},{"key":"2025042703273064000_2018.apr21_1.bcr-2018-224315.5","doi-asserted-by":"crossref","DOI":"10.1097\/MD.0000000000004287","article-title":"18F-FDG PET\/CT as a central tool in the shift from chronic Q fever to Coxiella burnetii persistent focalized infection: a consecutive case series","volume":"95","author":"Eldin","year":"2016","journal-title":"Medicine"},{"key":"2025042703273064000_2018.apr21_1.bcr-2018-224315.6","doi-asserted-by":"publisher","DOI":"10.1097\/INF.0000000000000861"},{"key":"2025042703273064000_2018.apr21_1.bcr-2018-224315.7","doi-asserted-by":"publisher","DOI":"10.1007\/s10096-007-0285-5"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2018-224315","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,27]],"date-time":"2025-04-27T10:27:37Z","timestamp":1745749657000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2018-224315"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,4,21]]},"references-count":7,"alternative-id":["10.1136\/bcr-2018-224315"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2018-224315","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2018,4,21]]}}}