{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,10]],"date-time":"2025-12-10T12:21:40Z","timestamp":1765369300907,"version":"3.40.4"},"reference-count":11,"publisher":"BMJ","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Reports"],"accepted":{"date-parts":[[2018,6,21]]},"abstract":"<jats:p>Jejunoileal follicular lymphomas (FLs) are rare and have been reported to undergo histological transformation (HT). We report a case of jejunoileal FL transformation into diffuse large B-cell lymphoma (DLBCL). An 82-year-old woman presented with a 5.5\u2009cm ulcerated jejunal mass, identified through double-balloon enteroscopy. The histopathology report revealed diffuse atypical lymphoid cells, which confirmed the presence of DLBCL. Neoplastic follicles confirmed the presence of FL. Genetic analysis revealed a match between the FL and DLBCL. Following a segmentectomy and chemotherapy, the patient is in remission. Based on this case, we should consider the possibility of jejunoileal FLs transforming into DLBCL.<\/jats:p>","DOI":"10.1136\/bcr-2018-224467","type":"journal-article","created":{"date-parts":[[2018,7,18]],"date-time":"2018-07-18T16:31:26Z","timestamp":1531931486000},"page":"bcr-2018-224467","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":3,"title":["Transformation of jejunoileal follicular lymphoma into diffuse large B-cell lymphoma detected using double-balloon enteroscopy"],"prefix":"10.1136","volume":"2018","author":[{"given":"Tomoyuki","family":"Nishimura","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9956-1358","authenticated-orcid":false,"given":"Toshio","family":"Kuwai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroki","family":"Imagawa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroshi","family":"Kohno","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2018,7,18]]},"reference":[{"key":"2025042705352819000_2018.jul18_1.bcr-2018-224467.1","first-page":"83","article-title":"WHO classification of tumours of haematopoietic and lymphoid tissues in 2008: an overview","volume":"102","author":"Sabattini","year":"2010","journal-title":"Pathologica"},{"key":"2025042705352819000_2018.jul18_1.bcr-2018-224467.2","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1016\/j.gie.2015.06.006","article-title":"Primary small-bowel follicular lymphoma with a stenosis: radiographic and endoscopic findings","volume":"83","author":"Kawasaki","year":"2016","journal-title":"Gastrointest Endosc"},{"key":"2025042705352819000_2018.jul18_1.bcr-2018-224467.3","doi-asserted-by":"publisher","DOI":"10.1111\/pin.12197"},{"key":"2025042705352819000_2018.jul18_1.bcr-2018-224467.4","unstructured":"Kitabatake H , Nagaya T , Tanaka N , et al ; Development of diffuse large B-cell lymphoma of the duodenum: changes in endoscopic findings during a 6-year follow-up."},{"key":"2025042705352819000_2018.jul18_1.bcr-2018-224467.5","doi-asserted-by":"publisher","DOI":"10.1111\/cas.12392"},{"key":"2025042705352819000_2018.jul18_1.bcr-2018-224467.6","doi-asserted-by":"crossref","first-page":"544","DOI":"10.1111\/j.1443-1661.2012.01386.x","article-title":"Histological diagnosis of follicular lymphoma by biopsy of small intestinal normal mucosa","volume":"25","author":"Okada","year":"2013","journal-title":"Dig Endosc"},{"key":"2025042705352819000_2018.jul18_1.bcr-2018-224467.7","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1055\/s-2007-995365","article-title":"Primary follicular lymphoma of the gastrointestinal tract: a retrospective case series","volume":"40","author":"Kodama","year":"2008","journal-title":"Endoscopy"},{"key":"2025042705352819000_2018.jul18_1.bcr-2018-224467.8","doi-asserted-by":"crossref","DOI":"10.1097\/MD.0000000000000165","article-title":"A case report of the histologic transformation of primary follicular lymphoma of the duodenum","volume":"93","author":"Akiyama","year":"2014","journal-title":"Medicine"},{"key":"2025042705352819000_2018.jul18_1.bcr-2018-224467.9","doi-asserted-by":"publisher","DOI":"10.1111\/bjh.13316"},{"key":"2025042705352819000_2018.jul18_1.bcr-2018-224467.10","doi-asserted-by":"crossref","first-page":"E323","DOI":"10.1055\/s-0042-100721","article-title":"Ileal follicular lymphoma with atypical endoscopic findings","volume":"4","author":"Yamada","year":"2016","journal-title":"Endosc Int Open"},{"key":"2025042705352819000_2018.jul18_1.bcr-2018-224467.11","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1007\/s12185-013-1273-4","article-title":"Clinical significance of jejunoileal involvement of non-Hodgkin\u2019s lymphoma detected by double-balloon enteroscopy","volume":"97","author":"Ibuka","year":"2013","journal-title":"Int J Hematol"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2018-224467","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,27]],"date-time":"2025-04-27T12:35:41Z","timestamp":1745757341000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2018-224467"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,7,18]]},"references-count":11,"alternative-id":["10.1136\/bcr-2018-224467"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2018-224467","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2018,7,18]]}}}