{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,26]],"date-time":"2026-03-26T12:52:13Z","timestamp":1774529533346,"version":"3.50.1"},"reference-count":37,"publisher":"BMJ","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Reports"],"accepted":{"date-parts":[[2018,7,28]]},"abstract":"<jats:p>An African American teenage boy during an acute sickle cell crisis spontaneously developed acute bifrontal epidural haematomas (EDHs) in addition to disseminated intravascular coagulation (DIC). The successfully evacuated EDH reaccumulated postoperatively. After multiple transfusions, the patient underwent repeat surgery. Subsequent maximal medical therapy was unable to significantly improve the patient\u2019s neurological status, and due to family wishes, care was withdrawn. EDH are the most common emergent neurosurgical complication of sickle cell disease (SCD). Twenty-two such cases have been previously reported. We present one further complicated by DIC leading to reaccumulation of the patient\u2019s EDH. An understanding of the mechanisms of EDH formation in SCD and their associated radiological findings could help clinicians identify when a patient is at high risk of EDH formation and thus offer the potential for early intervention prior to the development of an emergency.<\/jats:p>","DOI":"10.1136\/bcr-2018-224504","type":"journal-article","created":{"date-parts":[[2018,8,29]],"date-time":"2018-08-29T12:04:51Z","timestamp":1535544291000},"page":"bcr-2018-224504","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":8,"title":["Acute spontaneous intracranial epidural haematoma and disseminated intravascular coagulation in a paediatric sickle cell patient"],"prefix":"10.1136","volume":"2018","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7388-8798","authenticated-orcid":false,"given":"Christopher","family":"Banerjee","sequence":"first","affiliation":[{"name":"Department of Neurosurgery, Augusta University Medical College of Georgia, Augusta, Georgia, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"June","family":"Yowtak","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Augusta University Medical College of Georgia, Augusta, Georgia, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Diana","family":"Fridlyand","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Augusta University Medical College of Georgia, Augusta, Georgia, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cargill","family":"Alleyne Jr","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Augusta University Medical College of Georgia, Augusta, Georgia, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2018,8,29]]},"reference":[{"key":"2025082707125746000_2018.aug29_1.bcr-2018-224504.1","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-002-1355-9"},{"key":"2025082707125746000_2018.aug29_1.bcr-2018-224504.2","doi-asserted-by":"crossref","first-page":"S2","DOI":"10.1097\/00006123-200603001-00006","article-title":"Surgical management of acute epidural hematomas","volume":"58","author":"Bullock","year":"2006","journal-title":"Neurosurgery"},{"key":"2025082707125746000_2018.aug29_1.bcr-2018-224504.3","doi-asserted-by":"publisher","DOI":"10.4103\/2006-8808.110271"},{"key":"2025082707125746000_2018.aug29_1.bcr-2018-224504.4","doi-asserted-by":"publisher","DOI":"10.1259\/bjr\/58217479"},{"key":"2025082707125746000_2018.aug29_1.bcr-2018-224504.5","first-page":"E1156","article-title":"Spontaneous spinal epidural hematoma during pregnancy: case report and literature review","volume":"56","author":"Jea","year":"2005","journal-title":"Neurosurgery"},{"key":"2025082707125746000_2018.aug29_1.bcr-2018-224504.6","article-title":"[Spontaneous epidural hematoma in a patient undergoing hemodialysis: a case report]","volume":"55","author":"Shimokawa","year":"2003","journal-title":"No To Shinkei"},{"key":"2025082707125746000_2018.aug29_1.bcr-2018-224504.7","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/14.10.2499"},{"key":"2025082707125746000_2018.aug29_1.bcr-2018-224504.8","doi-asserted-by":"crossref","first-page":"1582","DOI":"10.1007\/s001340000658","article-title":"Cranial epidural hematoma in Paget\u2019s disease of the bone","volume":"26","author":"Mart\u00ednez-Lage","year":"2000","journal-title":"Intensive Care Med"},{"key":"2025082707125746000_2018.aug29_1.bcr-2018-224504.9","doi-asserted-by":"crossref","first-page":"791","DOI":"10.1016\/j.jocn.2003.12.002","article-title":"Non-traumatic spontaneous acute epidural haematoma\u2013report of two cases and review of the literature","volume":"11","author":"Ng","year":"2004","journal-title":"J Clin Neurosci"},{"key":"2025082707125746000_2018.aug29_1.bcr-2018-224504.10","article-title":"Metastatic hepatocellular carcinoma presenting as epidural hematoma: case report","volume":"49","author":"McIver","year":"2001","journal-title":"Neurosurgery"},{"key":"2025082707125746000_2018.aug29_1.bcr-2018-224504.11","doi-asserted-by":"crossref","first-page":"67","DOI":"10.3171\/jns.1968.28.1.0067","article-title":"Epidural hematoma secondary to frontal sinusitis. 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