{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,27]],"date-time":"2026-06-27T04:09:14Z","timestamp":1782533354190,"version":"3.54.5"},"reference-count":12,"publisher":"BMJ","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Reports"],"accepted":{"date-parts":[[2018,6,18]]},"abstract":"<jats:p>Gastrointestinal symptoms, such as anorexia, nausea, vomiting and abdominal pain, are very common in patients with Wernicke\u2019s encephalopathy (WE). Mild thiamine deficiency may have only gastrointestinal symptoms. We are reporting two patients with thiamine deficiency who predominantly had gastrointestinal symptoms. Case 1: a 38-year-old man had gastrointestinal problems for about 2\u20133 years. It gradually became severe. The patient came to the neurology outpatient department for his recent-onset vertigo and headache. Clinical examinations fulfilled Caine\u2019s criteria of WE. Gastrointestinal symptoms responded dramatically to intravenous thiamine. Case 2: a 21-year-old woman developed drug-induced hepatitis and gastritis. Associated nausea, vomiting and abdominal pain progressively increased over the weeks. The patient responded only to intravenous thiamine administration.<\/jats:p>\n               <jats:p>We suggest that a suspicion for gastrointestinal beriberi should arise if gastrointestinal symptoms (anorexia, nausea, vomiting and abdominal pain) are refractory to the usual therapies.<\/jats:p>","DOI":"10.1136\/bcr-2018-224841","type":"journal-article","created":{"date-parts":[[2018,7,7]],"date-time":"2018-07-07T02:55:36Z","timestamp":1530932136000},"page":"bcr-2018-224841","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":16,"title":["Gastrointestinal beriberi: a forme fruste of Wernicke\u2019s encephalopathy?"],"prefix":"10.1136","volume":"2018","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7322-904X","authenticated-orcid":false,"given":"Sanjay","family":"Prakash","sequence":"first","affiliation":[{"name":"Neurology, Smt B K Shah Medical Institute and Research Centre, Vadodara, Gujarat, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2018,7,6]]},"reference":[{"key":"2025082702174388000_2018.jul06_1.bcr-2018-224841.1","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(07)70104-7"},{"key":"2025082702174388000_2018.jul06_1.bcr-2018-224841.2","doi-asserted-by":"publisher","DOI":"10.1093\/alcalc\/agm149"},{"key":"2025082702174388000_2018.jul06_1.bcr-2018-224841.3","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-141-11-200412070-00035"},{"key":"2025082702174388000_2018.jul06_1.bcr-2018-224841.4","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.62.1.51"},{"key":"2025082702174388000_2018.jul06_1.bcr-2018-224841.5","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.49.4.341"},{"key":"2025082702174388000_2018.jul06_1.bcr-2018-224841.6","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/S0140-6736(47)91272-5","article-title":"Cerebral beriberi (Wernicke\u2019s encephalopathy); review of 52 cases in a Singapore prisoner-of-war hospital","volume":"1","author":"De Wardener","year":"1947","journal-title":"Lancet"},{"key":"2025082702174388000_2018.jul06_1.bcr-2018-224841.7","doi-asserted-by":"crossref","first-page":"401","DOI":"10.4103\/jnrp.jnrp_14_17","article-title":"Nonalcoholic wernicke\u2019s encephalopathy: a retrospective study from a tertiary care center in northern India","volume":"8","author":"Shah","year":"2017","journal-title":"J Neurosci Rural Pract"},{"key":"2025082702174388000_2018.jul06_1.bcr-2018-224841.8","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.1940.00190160002001"},{"key":"2025082702174388000_2018.jul06_1.bcr-2018-224841.9","first-page":"S150","article-title":"Ramadan fasting and digestive disorders: SEPAHAN systematic review no. 7","volume":"17","author":"Sadeghpour","year":"2012","journal-title":"J Res Med Sci"},{"key":"2025082702174388000_2018.jul06_1.bcr-2018-224841.10","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-1331.2010.03153.x"},{"key":"2025082702174388000_2018.jul06_1.bcr-2018-224841.11","doi-asserted-by":"crossref","first-page":"1204","DOI":"10.1111\/head.12838","article-title":"Chronic migraine responding to intravenous thiamine: a report of two cases","volume":"56","author":"Prakash","year":"2016","journal-title":"Headache"},{"key":"2025082702174388000_2018.jul06_1.bcr-2018-224841.12","doi-asserted-by":"publisher","DOI":"10.1089\/ars.2007.1766"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2018-224841","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T09:17:56Z","timestamp":1756286276000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2018-224841"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,7,6]]},"references-count":12,"alternative-id":["10.1136\/bcr-2018-224841"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2018-224841","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,7,6]]}}}