{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,30]],"date-time":"2025-12-30T11:06:57Z","timestamp":1767092817342,"version":"3.44.0"},"reference-count":9,"publisher":"BMJ","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Reports"],"accepted":{"date-parts":[[2018,7,17]]},"abstract":"<jats:p>The association of malignant lymphomas with non-necrotic epithelioid granulomas has been reported rarely since 1977. Hodgkin\u2019s disease-associated widespread cutaneous granuloma annulare (GA) has been reported in only eight patients. We report the second case of subcutaneous GA associated with Hodgkin\u2019s disease. A 73-year-old man with Epstein-Barr virus-associated Hodgkin\u2019s lymphoma and paraneoplastic subcutaneous GA, presented 3\u2009months after the diagnosis of malignancy. Examination revealed a large, broad erythematous, indurated, subcutaneous plaque spanning the majority of the left lower back and flank with no associated symptoms. Initial biopsy was suggestive of morphea. Prompted by positron emission tomography (PET) findings of increased fluorodeoxyglucose (FDG) uptake, a second, deeper biopsy was performed, revealing subcutaneous palisaded granulomatous dermatitis. After complete workup, the diagnosis most strongly suggested subcutaneous GA. This case highlights the importance of deep incisional biopsies, the fluorodeoxyglucose - positron emission tomography (FDG-PET) findings in GA and the rare association of GA with Hodgkin\u2019s disease which may signal the presence of malignancy.<\/jats:p>","DOI":"10.1136\/bcr-2018-224961","type":"journal-article","created":{"date-parts":[[2018,8,12]],"date-time":"2018-08-12T00:35:13Z","timestamp":1534034113000},"page":"bcr-2018-224961","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":11,"title":["Paraneoplastic granulomatous dermatitis in a patient with Hodgkin\u2019s disease: a diagnostic pitfall"],"prefix":"10.1136","volume":"2018","author":[{"given":"Mika M.","family":"Tabata","sequence":"first","affiliation":[{"name":"Department of Medicine, Stanford University School of Medicine, Stanford, California, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roberto A.","family":"Novoa","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Stanford University, Stanford, California, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kathryn J.","family":"Martires","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Stanford University, Stanford, California, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2018,8,11]]},"reference":[{"key":"2025082703141946000_2018.aug11_1.bcr-2018-224961.1","doi-asserted-by":"publisher","DOI":"10.1159\/000018318"},{"key":"2025082703141946000_2018.aug11_1.bcr-2018-224961.2","unstructured":"Reisenauer A , Korcheva V , White Jr C . White K , \"Non-infectious Granulomas.\" Dermatology: N.p. Elsevier Health Sciences, 2012:1563\u20136."},{"key":"2025082703141946000_2018.aug11_1.bcr-2018-224961.3","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1983.01650260033012"},{"key":"2025082703141946000_2018.aug11_1.bcr-2018-224961.4","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1111\/j.1365-2133.1977.tb14325.x","article-title":"Hodgkin\u2019s disease, seminoma of testicle and widespread granuloma annulare","volume":"97 Suppl 15","author":"Harman","year":"1977","journal-title":"Br J Dermatol"},{"key":"2025082703141946000_2018.aug11_1.bcr-2018-224961.5","doi-asserted-by":"crossref","unstructured":"Bassi A , Scarfi F , Galeone M , et al . Generalized Granuloma Annulare and Non-Hodgkin\u2019s Lymphoma. Acta Derm Venereol 2012.","DOI":"10.2340\/00015555-1510"},{"key":"2025082703141946000_2018.aug11_1.bcr-2018-224961.6","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2230.2008.02730.x"},{"key":"2025082703141946000_2018.aug11_1.bcr-2018-224961.7","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1111\/j.1346-8138.1996.tb04042.x","article-title":"Subcutaneous GA with Hodgkin\u2019s Disease","volume":"23","author":"Miyamoto","year":"1996","journal-title":"The Journal of Dermatology"},{"key":"2025082703141946000_2018.aug11_1.bcr-2018-224961.8","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1111\/j.1365-4362.1997.tb01127.x","article-title":"GA associated with Hodgkin\u2019s disease","volume":"36","author":"Setoyama","year":"1997","journal-title":"Int J Dermatol"},{"key":"2025082703141946000_2018.aug11_1.bcr-2018-224961.9","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1007\/s11552-010-9310-8","article-title":"Palmar fasciitis and polyarthritis syndrome in patients with ovarian cancer-a case report and review of the literature","volume":"6","author":"Qureshi","year":"2011","journal-title":"Hand"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2018-224961","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T10:14:29Z","timestamp":1756289669000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2018-224961"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,8,11]]},"references-count":9,"alternative-id":["10.1136\/bcr-2018-224961"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2018-224961","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2018,8,11]]}}}