{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T00:53:41Z","timestamp":1790211221902,"version":"4.1.0"},"reference-count":7,"publisher":"BMJ","issue":"12","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2019,12,11]]},"published-print":{"date-parts":[[2019,12]]},"abstract":"<jats:p>A 69-year-old woman with uncontrolled type 2 diabetes mellitus was admitted in the hospital for the management of urosepsis. Patient was overdosed with detemir insulin 1000 units inadvertently. Care provider was confused with volume and dose of the insulin by using insulin vial. Blood sugars were monitored closely every 30\u2009min\u20131\u2009hour for 24\u2009hours. Patient was treated with dextrose 5% and 10% continuous infusion; and hydrocortisone 75\u2009mg every 6\u2009hours for 24\u2009hours. The lowest blood sugar reached was 142\u2009mg\/dL (7.9 mmo\/L). Patient did not develop hypoglycaemia. Proper safety measures and mandatory nurse education about administration of insulin were implemented to prevent future occurrences.<\/jats:p>","DOI":"10.1136\/bcr-2018-224999","type":"journal-article","created":{"date-parts":[[2019,12,30]],"date-time":"2019-12-30T04:15:18Z","timestamp":1577679318000},"page":"e224999","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":2,"title":["Inadvertent iatrogenic insulin detemir 1000 units overdose in a hospitalised patient"],"prefix":"10.1136","volume":"12","author":[{"given":"Sudan","family":"Thapa","sequence":"first","affiliation":[{"name":"Internal Medicine, Monmouth Medical Center, Long Branch, New Jersey, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Germin","family":"Fahim","sequence":"additional","affiliation":[{"name":"Pharmacy, Monmouth Medical Center, Long Branch, New Jersey, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sudha","family":"Ganne","sequence":"additional","affiliation":[{"name":"Endocrinology, Monmouth Medical Center, Long Branch, New Jersey, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2019,12,29]]},"reference":[{"key":"2025082802293777000_12.12.e224999.1","doi-asserted-by":"crossref","first-page":"496","DOI":"10.1111\/bcp.12822","article-title":"Treatment of sulfonylurea and insulin overdose","volume":"81","author":"Klein-Schwartz","year":"2016","journal-title":"Br J Clin Pharmacol"},{"key":"2025082802293777000_12.12.e224999.2","doi-asserted-by":"publisher","DOI":"10.1097\/MJT.0b013e3181f4eadb"},{"key":"2025082802293777000_12.12.e224999.3","doi-asserted-by":"crossref","DOI":"10.1155\/2012\/904841","article-title":"Massive levemir (long-acting) insulin overdose: case report","volume":"2012","author":"Oduru","year":"2012","journal-title":"Case Rep Med"},{"key":"2025082802293777000_12.12.e224999.4","doi-asserted-by":"publisher","DOI":"10.3109\/15563658909038579"},{"key":"2025082802293777000_12.12.e224999.5","doi-asserted-by":"crossref","first-page":"650","DOI":"10.1111\/bcpt.12957","article-title":"A systematic review on insulin overdose cases: clinical course, complications and treatment options","volume":"122","author":"Johansen","year":"2018","journal-title":"Basic Clin Pharmacol Toxicol"},{"key":"2025082802293777000_12.12.e224999.6","doi-asserted-by":"publisher","DOI":"10.2337\/diacare.10.6.712"},{"key":"2025082802293777000_12.12.e224999.7","doi-asserted-by":"publisher","DOI":"10.1016\/0736-4679(93)90519-D"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2018-224999","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T09:29:41Z","timestamp":1756373381000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2018-224999"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,12]]},"references-count":7,"journal-issue":{"issue":"12","published-online":{"date-parts":[[2019,12,29]]},"published-print":{"date-parts":[[2019,12]]}},"alternative-id":["10.1136\/bcr-2018-224999"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2018-224999","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,12]]}}}