{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,29]],"date-time":"2025-08-29T00:02:40Z","timestamp":1756425760470,"version":"3.44.0"},"reference-count":15,"publisher":"BMJ","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Reports"],"accepted":{"date-parts":[[2018,5,9]]},"abstract":"<jats:p>Austrian syndrome is a rare medical condition characterised by the triad of pneumonia, meningitis and endocarditis due to <jats:italic>Streptococcus pneumoniae<\/jats:italic>. Native aortic valve insufficiency is the most common cause of cardiac failure in these patients, requiring valve replacement. We report a 52-year-old chronic alcoholic man who presented with fever, neck rigidity and loss of <jats:italic>c<\/jats:italic>onsciousness. Lumbar puncture revealed central nervous system infection while chest X-ray showed pneumonia. Blood and cerebrospinal fluid cultures revealed <jats:italic>S. pneumonia<\/jats:italic>. Transoesophageal echocardiography revealed aortic endocarditis with severe valve insufficiency. The patient underwent aortic valve replacement and was finally discharged after completion of 6\u2009weeks intravenous antibiotic treatment. Nowadays, Austrian syndrome is seen infrequently in the antibiotic era. However, clinicians should be aware of this syndrome as its early recognition and prompt combined medical and surgical treatment could reduce morbidity and mortality due to this potentially catastrophic clinical entity.<\/jats:p>","DOI":"10.1136\/bcr-2018-225010","type":"journal-article","created":{"date-parts":[[2018,5,30]],"date-time":"2018-05-30T07:37:00Z","timestamp":1527665820000},"page":"bcr-2018-225010","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["A chronic alcoholic man with high fever, neck rigidity and loss of consciousness: remember the Austrian syndrome a commonly unrecognised invasive pneumococcus triad"],"prefix":"10.1136","volume":"2018","author":[{"given":"Sarah P","family":"Georgiadou","sequence":"first","affiliation":[{"name":"Department of Medicine and Research Laboratory of Internal Medicine, School of Medicine, University of Thessaly, Larissa, Thessaly, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Efstratios","family":"Manoulakas","sequence":"additional","affiliation":[{"name":"Department of Medicine and Research Laboratory of Internal Medicine, School of Medicine, University of Thessaly, Larissa, Thessaly, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Konstantinos P","family":"Makaritsis","sequence":"additional","affiliation":[{"name":"Department of Medicine and Research Laboratory of Internal Medicine, School of Medicine, University of Thessaly, Larissa, Thessaly, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7075-8464","authenticated-orcid":false,"given":"George N","family":"Dalekos","sequence":"additional","affiliation":[{"name":"Department of Medicine and Research Laboratory of Internal Medicine, School of Medicine, University of Thessaly, Larissa, Thessaly, 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