{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T14:40:01Z","timestamp":1756305601830,"version":"3.44.0"},"reference-count":8,"publisher":"BMJ","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Reports"],"accepted":{"date-parts":[[2018,9,5]]},"abstract":"<jats:p>We report a case of Kimura\u2019s disease in a 65-year-old woman who presented with generalised itching, abdominal pain, facial puffiness, difficulty in swallowing and loss of appetite. She was found to have generalised lymphadenopathy and a fine-needle aspiration cytology initially done revealed \u2018reactive lymphadenitis\u2019 which was inconclusive. PET-CT done showed features suggestive of lymphoma. Hence, lymph node biopsy was done for confirmation and incidentally after immunohistochemistry staining it turned out to be Kimura\u2019s disease. High-dose steroid therapy was started and patient showed dramatic clinical and symptomatic improvement. Kimura\u2019s disease almost always presents as cervical lymphadenopathy and usually never causes compressive symptoms. Our patient presented with compressive symptoms and generalised lymphadenopathy which is a rarity.<\/jats:p>","DOI":"10.1136\/bcr-2018-225020","type":"journal-article","created":{"date-parts":[[2018,10,2]],"date-time":"2018-10-02T09:19:32Z","timestamp":1538471972000},"page":"bcr-2018-225020","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":4,"title":["Unusual and rare case of generalised lymphadenopathy: Kimura\u2019s disease"],"prefix":"10.1136","volume":"2018","author":[{"given":"Judah","family":"Arul","sequence":"first","affiliation":[{"name":"General Medicine, Sri Ramachandra Medical College and Research Institute, Chennai, Tamil Nadu, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Narayanasamy","family":"Senthil","sequence":"additional","affiliation":[{"name":"General Medicine, Sri Ramachandra Medical College and Research Institute, Chennai, Tamil Nadu, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lakshmi","family":"Marappa","sequence":"additional","affiliation":[{"name":"General Medicine, Sri Ramachandra Medical College and Research Institute, Chennai, Tamil Nadu, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2018,10,2]]},"reference":[{"key":"2025082707014087000_2018.oct02_1.bcr-2018-225020.1","first-page":"179","article-title":"On the unusual granulation combined with hyperplastic changes of lymphatic tissues","volume":"37","author":"Kimura","year":"1948","journal-title":"Trans Soc Pathol Jpn"},{"key":"2025082707014087000_2018.oct02_1.bcr-2018-225020.2","doi-asserted-by":"crossref","unstructured":"Chen QL , Li CX , Shao B , et al . Expression of the interleukin-21 and phosphorylated extracellular signal regulated kinase 1\/2 in Kimura disease. J Clin Pathol 2017;70.doi:10.1136\/jclinpath-2016-204096","DOI":"10.1136\/jclinpath-2016-204096"},{"key":"2025082707014087000_2018.oct02_1.bcr-2018-225020.3","unstructured":"Larroche C , Bletry O , 2018. \u201cKimura\u2019s disease,\u201d orphanet encyclopedia. http:\/\/www.orpha.net\/data\/patho\/GB\/uk-kimura.pdf"},{"key":"2025082707014087000_2018.oct02_1.bcr-2018-225020.4","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1186\/s12893-017-0260-8","article-title":"Kimura\u2019s disease affecting the axillary lymph nodes: a case report","volume":"17","author":"Kuroda","year":"2017","journal-title":"BMC Surg"},{"key":"2025082707014087000_2018.oct02_1.bcr-2018-225020.5","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-200404000-00010"},{"key":"2025082707014087000_2018.oct02_1.bcr-2018-225020.6","doi-asserted-by":"crossref","first-page":"89","DOI":"10.4103\/0971-5851.73598","article-title":"Kimura\u2019s disease: an uncommon cause of lymphadenopathy","volume":"31","author":"Kumar","year":"2010","journal-title":"Indian J Med Paediatr Oncol"},{"key":"2025082707014087000_2018.oct02_1.bcr-2018-225020.7","doi-asserted-by":"crossref","first-page":"775","DOI":"10.2169\/internalmedicine.45.1618","article-title":"Kimura\u2019s disease with generalized lymphadenopathy demonstrated by positron emission tomography scan","volume":"45","author":"Wang","year":"2006","journal-title":"Intern Med"},{"key":"2025082707014087000_2018.oct02_1.bcr-2018-225020.8","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1007\/s13139-014-0285-1","article-title":"Kimura Disease Simulating Hodgkin\u2019s Lymphoma on (18)F FDG PET-CT: Report of a Case","volume":"48","author":"Yang","year":"2014","journal-title":"Nucl Med Mol Imaging"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2018-225020","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T14:01:48Z","timestamp":1756303308000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2018-225020"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,10,2]]},"references-count":8,"alternative-id":["10.1136\/bcr-2018-225020"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2018-225020","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2018,10,2]]}}}