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A 7-year-old-PJS boy presented with recurrent episodes of colicky abdominal pain and melena requiring repeated blood transfusions. Abdominal CT scan revealed multiple jejunal polyps with jejunoileal intussusception. On exploration, the intussuscepted bowel was resected along with its mesentery and anastomosed. Simultaneously, multiple enterotomies with resection of palpable polyps were performed. The resected bowel showed well-differentiated stage 2A adenocarcinoma with clear resected margins. Postoperatively, the complaints were relieved. On follow-up, he was asymptomatic and is now on yearly cancer surveillance. This is probably the youngest reported case of small bowel cancer in PJS.<\/jats:p>","DOI":"10.1136\/bcr-2018-225076","type":"journal-article","created":{"date-parts":[[2018,12,18]],"date-time":"2018-12-18T17:19:47Z","timestamp":1545153587000},"page":"e225076","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":3,"title":["Peutz-Jeghers syndrome: need for early screening"],"prefix":"10.1136","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3400-3253","authenticated-orcid":false,"given":"Kashish","family":"Khanna","sequence":"first","affiliation":[{"name":"Department of Pediatric Surgery, All India Institute of Medical Sciences, New Delhi, Delhi, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vikram","family":"Khanna","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery, Lady Hardinge Medical College, New Delhi, Delhi, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Veereshwar","family":"Bhatnagar","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery, All India Institute of Medical Sciences, New Delhi, Delhi, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2018,12,13]]},"reference":[{"key":"2025082710271194000_11.1.e225076.1","doi-asserted-by":"publisher","DOI":"10.1007\/s00018-006-6080-0"},{"key":"2025082710271194000_11.1.e225076.2","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-06-0083"},{"key":"2025082710271194000_11.1.e225076.3","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2005.11.005"},{"key":"2025082710271194000_11.1.e225076.4","doi-asserted-by":"publisher","DOI":"10.1053\/gast.2000.20228"},{"key":"2025082710271194000_11.1.e225076.5","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1097\/MPH.0b013e318282db11","article-title":"Unusually early presentation of small-bowel adenocarcinoma in a patient with Peutz-Jeghers syndrome","volume":"35","author":"Wangler","year":"2013","journal-title":"J Pediatr Hematol Oncol"},{"key":"2025082710271194000_11.1.e225076.6","first-page":"159","article-title":"Peutz-jeghers syndrome and colon cancer in a 10-year-old girl: implications for when and how to start screening?","volume":"9","author":"Saranrittichai","year":"2008","journal-title":"Asian Pac J Cancer Prev"},{"key":"2025082710271194000_11.1.e225076.7","doi-asserted-by":"publisher","DOI":"10.1097\/MPG.0b013e318271643c"},{"key":"2025082710271194000_11.1.e225076.8","doi-asserted-by":"publisher","DOI":"10.1038\/ajg.2014.435"},{"key":"2025082710271194000_11.1.e225076.9","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-17-0790"},{"key":"2025082710271194000_11.1.e225076.10","doi-asserted-by":"crossref","first-page":"e137","DOI":"10.1097\/MPH.0b013e3182467f3e","article-title":"Sporadic adenocarcinoma of the colon in children: case series and review of the literature","volume":"34","author":"Blumer","year":"2012","journal-title":"J Pediatr Hematol Oncol"},{"key":"2025082710271194000_11.1.e225076.11","doi-asserted-by":"publisher","DOI":"10.1136\/gut.2009.198499"},{"key":"2025082710271194000_11.1.e225076.12","doi-asserted-by":"publisher","DOI":"10.1097\/00005176-200408000-00027"},{"key":"2025082710271194000_11.1.e225076.13","doi-asserted-by":"publisher","DOI":"10.1097\/DCR.0b013e318233a11f"},{"key":"2025082710271194000_11.1.e225076.14","doi-asserted-by":"publisher","DOI":"10.1038\/ajg.2009.725"},{"key":"2025082710271194000_11.1.e225076.15","doi-asserted-by":"crossref","first-page":"509","DOI":"10.4251\/wjgo.v8.i6.509","article-title":"Genetic risks and familial associations of small bowel carcinoma","volume":"8","author":"Shenoy","year":"2016","journal-title":"World J Gastrointest Oncol"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/data.bmj.org\/tdm\/10.1136\/bcr-2018-225076","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2018-225076","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T17:27:16Z","timestamp":1756315636000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2018-225076"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,11]]},"references-count":15,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2018,12,13]]},"published-print":{"date-parts":[[2018,11]]}},"alternative-id":["10.1136\/bcr-2018-225076"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2018-225076","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2018,11]]}}}