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Extensive investigations were performed to exclude infective, inflammatory or malignant aetiologies for these symptoms. She was diagnosed with PCI on her colonoscopy and was subsequently screened for secondary causes. Our patient was diagnosed with the limited cutaneous (CREST) variant of systemic scleroderma. This case report illustrates that PCI could be an uncommon presentation of systemic sclerosis, therefore clinicians should be aware of the association between these conditions.<\/jats:p>","DOI":"10.1136\/bcr-2018-225175","type":"journal-article","created":{"date-parts":[[2018,9,29]],"date-time":"2018-09-29T06:51:29Z","timestamp":1538203889000},"page":"bcr-2018-225175","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":6,"title":["Pneumatosis cystoides intestinalis (PCI) in a patient with undiagnosed systemic sclerosis"],"prefix":"10.1136","volume":"2018","author":[{"given":"Gurpreet","family":"Singh","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher","family":"Johnson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rosie","family":"Gill","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"De Cruz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2018,9,28]]},"reference":[{"key":"2025042706255547000_2018.sep28_1.bcr-2018-225175.1","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1186\/s13256-017-1198-2","article-title":"Pneumatosis cystoides intestinalis presenting as pneumoperitoneum in a patient with chronic obstructive pulmonary disease: a case report","volume":"11","author":"Iida","year":"2017","journal-title":"J Med Case Rep"},{"key":"2025042706255547000_2018.sep28_1.bcr-2018-225175.2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.280.6216.763"},{"key":"2025042706255547000_2018.sep28_1.bcr-2018-225175.3","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1111\/j.1365-2133.1990.tb01445.x","article-title":"Autoantibodies to nucleolar antigens in systemic scleroderma: clinical correlations","volume":"123","author":"B\u0142aszczyk","year":"1990","journal-title":"Br J Dermatol"},{"key":"2025042706255547000_2018.sep28_1.bcr-2018-225175.4","doi-asserted-by":"publisher","DOI":"10.1097\/00002281-200311000-00016"},{"key":"2025042706255547000_2018.sep28_1.bcr-2018-225175.5","doi-asserted-by":"publisher","DOI":"10.1007\/s10354-007-0451-5"},{"key":"2025042706255547000_2018.sep28_1.bcr-2018-225175.6","doi-asserted-by":"crossref","first-page":"9216","DOI":"10.4076\/1752-1947-3-9216","article-title":"Pneumatosis cystoides intestinalis of the ascending colon related to acarbose treatment: a case report","volume":"3","author":"Vogel","year":"2009","journal-title":"J Med Case Rep"},{"key":"2025042706255547000_2018.sep28_1.bcr-2018-225175.7","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1155\/2013\/353245","article-title":"Pneumatosis cystoides intestinalis: a rare benign cause of pneumoperitoneum","volume":"2013","author":"Devgun","year":"2013","journal-title":"Case Rep Radiol"},{"key":"2025042706255547000_2018.sep28_1.bcr-2018-225175.8","unstructured":"NEJM, 2018. 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