{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,29]],"date-time":"2026-08-29T17:54:37Z","timestamp":1788026077936,"version":"build-2784847793"},"reference-count":12,"publisher":"BMJ","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Reports"],"accepted":{"date-parts":[[2018,7,3]]},"abstract":"<jats:p>Parathyroid or hypercalcaemic crisis is a rare presenting manifestation of primary hyperparathyroidism and usually seen in relation to parathyroid carcinoma and multiple myeloma. We present a middle-aged woman with extreme hypercalcaemia due to parathyroid adenoma presenting as acute kidney injury. This case highlights the need to consider primary hyperparathyroidism in differentials of a patient presenting with severe hypercalcaemia and renal dysfunction. Also this is the second reported case in literature of a patient surviving such extreme hypercalcaemia due to parathyroid adenoma.<\/jats:p>","DOI":"10.1136\/bcr-2018-225235","type":"journal-article","created":{"date-parts":[[2018,7,31]],"date-time":"2018-07-31T02:55:15Z","timestamp":1533005715000},"page":"bcr-2018-225235","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":5,"title":["Acute kidney injury associated with hypercalcaemic crisis in a patient with primary hyperparathyroidism"],"prefix":"10.1136","volume":"2018","author":[{"given":"Jasmine","family":"Sethi","sequence":"first","affiliation":[{"name":"Department of Nephrology, Postgraduate Institute of Medical Education and Research, Chandigarh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vivek","family":"Kumar","sequence":"additional","affiliation":[{"name":"Department of Nephrology, Postgraduate Institute of Medical Education and Research, Chandigarh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manish","family":"Rathi","sequence":"additional","affiliation":[{"name":"Department of Nephrology, Postgraduate Institute of Medical Education and Research, Chandigarh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Krishan Lal","family":"Gupta","sequence":"additional","affiliation":[{"name":"Department of Nephrology, Postgraduate Institute of Medical Education and Research, Chandigarh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2018,7,30]]},"reference":[{"key":"2025082722291672000_2018.jul30_1.bcr-2018-225235.1","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.141.7.696"},{"key":"2025082722291672000_2018.jul30_1.bcr-2018-225235.2","first-page":"494","article-title":"Hypercalcaemic crisis due to primary hyperparathyroidism - a systematic literature review and case report","volume":"63","author":"Gurrado","year":"2012","journal-title":"Endokrynol Pol"},{"key":"2025082722291672000_2018.jul30_1.bcr-2018-225235.3","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1111\/j.1365-2796.2005.01506.x","article-title":"Surviving extreme hypercalcaemia-a case report and review of the literature","volume":"258","author":"Marienhagen","year":"2005","journal-title":"J Intern Med"},{"key":"2025082722291672000_2018.jul30_1.bcr-2018-225235.4","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199204303261806"},{"key":"2025082722291672000_2018.jul30_1.bcr-2018-225235.5","doi-asserted-by":"publisher","DOI":"10.1210\/jc.77.6.1445"},{"key":"2025082722291672000_2018.jul30_1.bcr-2018-225235.6","first-page":"59","article-title":"Management and surgical treatment of parathyroid crisis secondary to parathyroid tumors: report of four cases","volume":"4","author":"Ameerudden","year":"2011","journal-title":"Int Med Case Rep J"},{"key":"2025082722291672000_2018.jul30_1.bcr-2018-225235.7","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9343(97)80047-2"},{"key":"2025082722291672000_2018.jul30_1.bcr-2018-225235.8","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1007\/BF00255605","article-title":"Calcium free hemodialysis: an effective therapy in hypercalcemic crisis-report of 4 cases","volume":"15","author":"Kaiser","year":"1989","journal-title":"Intensive Care Med"},{"key":"2025082722291672000_2018.jul30_1.bcr-2018-225235.9","doi-asserted-by":"crossref","first-page":"1174.e1","DOI":"10.1016\/j.ajem.2009.01.026","article-title":"Hypercalcemic crisis successfully treated with prompt calcium-free hemodialysis","volume":"27","author":"Wang","year":"2009","journal-title":"Am J Emerg Med"},{"key":"2025082722291672000_2018.jul30_1.bcr-2018-225235.10","doi-asserted-by":"publisher","DOI":"10.1111\/j.1542-4758.2006.00125.x"},{"key":"2025082722291672000_2018.jul30_1.bcr-2018-225235.11","first-page":"190","article-title":"Influence of changes in ionized calcium on cardiovascular reactivity during hemodialysis","volume":"47","author":"van Kuijk","year":"1997","journal-title":"Clin Nephrol"},{"issue":"Suppl 17","key":"2025082722291672000_2018.jul30_1.bcr-2018-225235.12","doi-asserted-by":"crossref","first-page":"S3","DOI":"10.1681\/ASN.V12suppl_1s3","article-title":"Hypercalcemic crisis","volume":"12","author":"Ziegler","year":"2001","journal-title":"J Am Soc Nephrol"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2018-225235","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T05:29:29Z","timestamp":1756358969000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2018-225235"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,7,30]]},"references-count":12,"alternative-id":["10.1136\/bcr-2018-225235"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2018-225235","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,7,30]]}}}