{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T12:42:52Z","timestamp":1756384972396,"version":"3.44.0"},"reference-count":8,"publisher":"BMJ","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Reports"],"accepted":{"date-parts":[[2018,6,28]]},"abstract":"<jats:p>Infection-related glomerulonephritis results from glomerular immune complex deposition due to a variety of potential pathogens. Poststreptococcal glomerulonephritis is the best known example. We present a case of acute infection-related glomerulonephritis associated with disseminated gonococcal infection in a sexually active 13-year-old girl, the first report of such an association in the absence of endocarditis. The patient presented with features of acute disseminated gonococcal infection including fever, hypotension, tenosynovitis, polyarthralgias and petechiae. She developed hypocomplementemic glomerulonephritis synchronous with the acute infection. The renal biopsy revealed a diffuse endocapillary proliferative and exudative glomerulonephritis with subepithelial electron-dense humps and granular glomerular capillary wall staining for C3 and IgG, typical of acute postinfectious glomerulonephritis. After treatment and resolution of the gonococcal infection, the serum creatinine, complement levels and urine sediment normalised. The only residual renal damage 16 months later was low-grade proteinuria.<\/jats:p>","DOI":"10.1136\/bcr-2018-225371","type":"journal-article","created":{"date-parts":[[2018,7,18]],"date-time":"2018-07-18T11:52:53Z","timestamp":1531914773000},"page":"bcr-2018-225371","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Acute infection-related glomerulonephritis with disseminated gonococcal infection in a 13-year-old girl"],"prefix":"10.1136","volume":"2018","author":[{"given":"Asif","family":"Noor","sequence":"first","affiliation":[{"name":"Department of Pediatrics, NYU Winthrop Hospital, Mineola, New York, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leonard R","family":"Krilov","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, NYU Winthrop Hospital, Mineola, New York, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vivette","family":"D\u2019Agati","sequence":"additional","affiliation":[{"name":"Department of Pathology, Columbia University Medical Center, New York City, New York, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manju","family":"Chandra","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, NYU Winthrop Hospital, Mineola, New York, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2018,7,18]]},"reference":[{"key":"2025082805072548000_2018.jul18_1.bcr-2018-225371.1","doi-asserted-by":"crossref","first-page":"793","DOI":"10.1016\/0002-9343(80)90273-9","article-title":"Gonococcal endocarditis associated with immune complex glomerulonephritis","volume":"68","author":"Ebright","year":"1980","journal-title":"Am J Med"},{"key":"2025082805072548000_2018.jul18_1.bcr-2018-225371.2","unstructured":"Charles RW . Gonococcal infections. In: Feigin and Cherry\u2019s textbook of pediatric infectious diseases, chapter 89. 2014:1271\u2013301."},{"key":"2025082805072548000_2018.jul18_1.bcr-2018-225371.3","first-page":"741","article-title":"Neisseria gonorrhoeae","volume":"126","author":"Rice","year":"2012","journal-title":"Principles and Practice of Pediatric Infectious Diseases"},{"key":"2025082805072548000_2018.jul18_1.bcr-2018-225371.4","first-page":"336","article-title":"Post-infectious glomerulonephritis in pediatric patients over two decades: severity-associated features","volume":"18","author":"Dagan","year":"2016","journal-title":"Isr Med Assoc J"},{"key":"2025082805072548000_2018.jul18_1.bcr-2018-225371.5","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.1987.00370020099044"},{"key":"2025082805072548000_2018.jul18_1.bcr-2018-225371.6","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1097\/00005792-198311000-00005","article-title":"Disseminated gonococcal infection: a prospective analysis of 49 patients and a review of pathophysiology and immune mechanisms","volume":"1983","author":"O\u2019Brien","year":"1983","journal-title":"Medicine"},{"key":"2025082805072548000_2018.jul18_1.bcr-2018-225371.7","doi-asserted-by":"crossref","first-page":"792","DOI":"10.1038\/ki.2012.407","article-title":"Bacterial infection-related glomerulonephritis in adults","volume":"83","author":"Nasr","year":"2013","journal-title":"Kidney Int Pages"},{"key":"2025082805072548000_2018.jul18_1.bcr-2018-225371.8","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1016\/S0140-6736(81)91788-8","article-title":"Attack rate of poststreptococcal nephritis in families. 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