{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,7]],"date-time":"2026-11-07T06:00:56Z","timestamp":1794031256112,"version":"4.8.0"},"reference-count":17,"publisher":"BMJ","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Reports"],"accepted":{"date-parts":[[2018,7,28]]},"abstract":"<jats:p>A previously healthy 21-year-old man presented with an 8-month history of weight loss, lethargy and dysuria unresponsive to empiric antibiotics and paraurethral drainage of a prostatic abscess. Urinalysis showed pyuria, but cultures failed to grow any organisms. Additionally, he developed new onset sensorineural hearing loss. CT of the chest showed two right-sided cavitary lesions. CT of the abdomen and pelvis demonstrated a prostatic abscess. A prostate biopsy demonstrated necrotising granulomatous prostatitis. A lung biopsy showed necrotising granulomatous inflammation. He was diagnosed with granulomatosis with polyangiitis (GPA). He was successfully treated with rituximab and prednisone. At 6-month follow-up, he continued to be in remission with resolution of his symptoms. This case demonstrates a rare presentation of prostatitis as the presenting symptom of GPA. As far as we know, this case is the first documented report of rituximab and prednisone as successful therapy for prostatitis secondary to GPA.<\/jats:p>","DOI":"10.1136\/bcr-2018-225379","type":"journal-article","created":{"date-parts":[[2018,8,14]],"date-time":"2018-08-14T14:40:15Z","timestamp":1534257615000},"page":"bcr-2018-225379","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":2,"title":["Prostatitis, a rare presentation of granulomatosis with polyangiitis, successfully treated with rituximab and prednisone"],"prefix":"10.1136","volume":"2018","author":[{"given":"Muhammad Saad","family":"Shaukat","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anthony J","family":"Ocon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruben A","family":"Peredo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Birju D","family":"Bhatt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2018,8,14]]},"reference":[{"key":"2025042705534209000_2018.aug14_1.bcr-2018-225379.1","doi-asserted-by":"publisher","DOI":"10.1016\/j.autrev.2014.08.017"},{"key":"2025042705534209000_2018.aug14_1.bcr-2018-225379.2","doi-asserted-by":"publisher","DOI":"10.1002\/art.37715"},{"key":"2025042705534209000_2018.aug14_1.bcr-2018-225379.3","first-page":"1310","volume-title":"Rheumatology","volume":"2","author":"Hochberg","year":"2015"},{"key":"2025042705534209000_2018.aug14_1.bcr-2018-225379.4","doi-asserted-by":"crossref","first-page":"897","DOI":"10.1016\/j.autrev.2015.05.012","article-title":"Urologic and male genital manifestations of granulomatosis with polyangiitis","volume":"14","author":"Alba","year":"2015","journal-title":"Autoimmun Rev"},{"key":"2025042705534209000_2018.aug14_1.bcr-2018-225379.5","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1007\/s00296-003-0343-y","article-title":"Wegener\u2019s granulomatosis of the prostate gland","volume":"24","author":"Gunnarsson","year":"2004","journal-title":"Rheumatol Int"},{"key":"2025042705534209000_2018.aug14_1.bcr-2018-225379.6","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1097\/MD.0b013e318239add6","article-title":"Urogenital manifestations in Wegener granulomatosis: a study of 11 cases and review of the literature","volume":"91","author":"Dufour","year":"2012","journal-title":"Medicine"},{"key":"2025042705534209000_2018.aug14_1.bcr-2018-225379.7","first-page":"w14030","article-title":"Cyclophosphamide: as bad as its reputation? 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