{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T09:10:06Z","timestamp":1756285806373,"version":"3.44.0"},"reference-count":12,"publisher":"BMJ","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Reports"],"accepted":{"date-parts":[[2018,5,20]]},"abstract":"<jats:p>Nocardiosis is a rare, predominantly opportunistic, suppurative disease caused by bacteria of the order Actinomycetales. There are currently more than 100 species of <jats:italic>Nocardia<\/jats:italic> described, less than half are pathogenic to humans. Cutaneous nocardiosis can be caused by direct inoculation from a contaminated material or by secondary dissemination. The authors present a 70-year-old man with an autoimmune haemolytic anaemia treated with prednisolone and azathioprine. The patient presented multiple erythematous tender nodules with linear distribution and proximal progression along the left upper limb with 2 months of evolution. The skin biopsy revealed non-specific inflammation with areas of abscess. Culture was positive for bacteria of the genus <jats:italic>Nocardia<\/jats:italic>, and molecular techniques revealed <jats:italic>Nocardia grenadensis<\/jats:italic>. The patient was treated with minocycline with good response, but the disease recurred. <jats:italic>N. grenadensis<\/jats:italic> was first identified in 2012 in a bioprospecting process. The authors now describe the first case of cutaneous nocardiosis caused by <jats:italic>N. grenadensis<\/jats:italic>.<\/jats:p>","DOI":"10.1136\/bcr-2018-225441","type":"journal-article","created":{"date-parts":[[2018,6,4]],"date-time":"2018-06-04T09:28:30Z","timestamp":1528104510000},"page":"bcr-2018-225441","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Cutaneous nocardiosis by a new pathogenic species: <i>Nocardia grenadensis<\/i>"],"prefix":"10.1136","volume":"2018","author":[{"given":"Rui Pedro","family":"Santos","sequence":"first","affiliation":[{"name":"Department of Dermatology, Hospital de Braga, Braga, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juliana","family":"Almeida","sequence":"additional","affiliation":[{"name":"Department of Clinical Pathology, Hospital de Braga, Braga, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6561-5338","authenticated-orcid":false,"given":"Filipa Tavares","family":"Almeida","sequence":"additional","affiliation":[{"name":"Dermatovenereology, Hospital de Braga, Braga, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria da Luz","family":"Duarte","sequence":"additional","affiliation":[{"name":"Dermatology, Hospital de Braga, Braga, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2018,6,4]]},"reference":[{"key":"2025082701412151000_2018.jun01_1.bcr-2018-225441.1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-4632.2010.04554.x"},{"key":"2025082701412151000_2018.jun01_1.bcr-2018-225441.2","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1016\/j.jdcr.2015.03.001","article-title":"Lymphangitic papules caused by Nocardia takedensis","volume":"1","author":"Chung","year":"2015","journal-title":"JAAD Case Rep"},{"key":"2025082701412151000_2018.jun01_1.bcr-2018-225441.3","doi-asserted-by":"crossref","unstructured":"Ercibengoa M , Vicente D , Marim\u00f3n JM , et al . 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JMM Case Rep 2016;3.doi:10.1099\/jmmcr.0.005022","DOI":"10.1099\/jmmcr.0.005022"},{"key":"2025082701412151000_2018.jun01_1.bcr-2018-225441.4","doi-asserted-by":"publisher","DOI":"10.1007\/s15010-009-9193-9"},{"key":"2025082701412151000_2018.jun01_1.bcr-2018-225441.5","doi-asserted-by":"publisher","DOI":"10.1099\/ijs.0.030684-0"},{"key":"2025082701412151000_2018.jun01_1.bcr-2018-225441.6","doi-asserted-by":"publisher","DOI":"10.1016\/j.mayocp.2011.11.016"},{"key":"2025082701412151000_2018.jun01_1.bcr-2018-225441.7","doi-asserted-by":"crossref","first-page":"471","DOI":"10.5021\/ad.2017.29.4.471","article-title":"Primary Cutaneous Nocardiosis Caused by Nocardia takedensis","volume":"29","author":"Lee","year":"2017","journal-title":"Ann Dermatol"},{"key":"2025082701412151000_2018.jun01_1.bcr-2018-225441.8","doi-asserted-by":"crossref","first-page":"535","DOI":"10.4103\/0378-6323.82409","article-title":"Sporotrichoid nocardiosis with cutaneous dissemination","volume":"77","author":"Bosamiya","year":"2011","journal-title":"Indian J Dermatol Venereol Leprol"},{"key":"2025082701412151000_2018.jun01_1.bcr-2018-225441.9","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-4632.2008.03728.x"},{"key":"2025082701412151000_2018.jun01_1.bcr-2018-225441.10","doi-asserted-by":"crossref","first-page":"e97","DOI":"10.1111\/ajd.12468","article-title":"Primary cutaneous nocardiosis caused by Nocardia takedensis with pulmonary dissemination in an immunosuppressed patient","volume":"58","author":"Benzaquen","year":"2017","journal-title":"Australas J Dermatol"},{"key":"2025082701412151000_2018.jun01_1.bcr-2018-225441.11","doi-asserted-by":"publisher","DOI":"10.1111\/j.1346-8138.2010.01166.x"},{"key":"2025082701412151000_2018.jun01_1.bcr-2018-225441.12","doi-asserted-by":"publisher","DOI":"10.1086\/657399"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2018-225441","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T08:41:34Z","timestamp":1756284094000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2018-225441"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,6,4]]},"references-count":12,"alternative-id":["10.1136\/bcr-2018-225441"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2018-225441","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2018,6,4]]}}}