{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,28]],"date-time":"2025-04-28T04:01:42Z","timestamp":1745812902602,"version":"3.40.4"},"reference-count":10,"publisher":"BMJ","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Reports"],"accepted":{"date-parts":[[2018,6,2]]},"abstract":"<jats:p>Cicatricial pemphigoid (CP) is a chronic, autoimmune, subepidermal blistering disease with predominant mucosal involvement. In this article, we report a young patient with mucosal and extensive cutaneous involvement in the form of large erosions mimicking those of pemphigus vulgaris thus leading to diagnostic dilemma. We were unable to find any other previous reports with such extensive cutaneous erosions mimicking those of pemphigus vulgaris. Laminin 5 was the antigen found on knockout substrate testing. Antiepiligrin CP is a distinct subtype of CP with antibodies against laminin 5. This subtype is mostly associated with malignancy but no underlying malignancy was found in our case. Present report also highlights the importance of knockout substrate testing when immunoblot is not available.<\/jats:p>","DOI":"10.1136\/bcr-2018-225446","type":"journal-article","created":{"date-parts":[[2018,6,21]],"date-time":"2018-06-21T14:05:05Z","timestamp":1529589905000},"page":"bcr-2018-225446","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["A case of antiepiligrin cicatricial pemphigoid with extensive cutaneous erosions mimicking pemphigus vulgaris"],"prefix":"10.1136","volume":"2018","author":[{"given":"Swastika","family":"Suvirya","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sucheta","family":"Pathania","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kiran Preet","family":"Malhotra","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Parul","family":"Verma","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2018,6,21]]},"reference":[{"key":"2025042703573357000_2018.jun21_1.bcr-2018-225446.1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.138.3.370"},{"key":"2025042703573357000_2018.jun21_1.bcr-2018-225446.2","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1111\/j.1525-1470.2009.01079.x","article-title":"Early onset childhood cicatricial pemphigoid: a case report and review of the literature","volume":"27","author":"Kharfi","year":"2010","journal-title":"Pediatr Dermatol"},{"key":"2025042703573357000_2018.jun21_1.bcr-2018-225446.3","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1016\/j.det.2011.03.011","article-title":"Pathogenesis of mucous membrane pemphigoid","volume":"29","author":"Kourosh","year":"2011","journal-title":"Dermatol Clin"},{"key":"2025042703573357000_2018.jun21_1.bcr-2018-225446.4","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1111\/j.1346-8138.2006.00170.x","article-title":"Cicatricial pemphigoid with widespread bullous eruption","volume":"33","author":"Inaoki","year":"2006","journal-title":"J Dermatol"},{"key":"2025042703573357000_2018.jun21_1.bcr-2018-225446.5","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/S0161-6420(81)35069-6","volume":"88","author":"Mondino","year":"1981","journal-title":"Ophthalmology"},{"key":"2025042703573357000_2018.jun21_1.bcr-2018-225446.6","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1994.01690120057008"},{"key":"2025042703573357000_2018.jun21_1.bcr-2018-225446.7","doi-asserted-by":"publisher","DOI":"10.1097\/00005792-200305000-00004"},{"key":"2025042703573357000_2018.jun21_1.bcr-2018-225446.8","doi-asserted-by":"crossref","first-page":"484","DOI":"10.2340\/00015555-0506","article-title":"Two cases of anti-epiligrin cicatricial pemphigoid with and without associated malignancy","volume":"88","author":"Fukushima","year":"2008","journal-title":"Acta Derm Venereol"},{"key":"2025042703573357000_2018.jun21_1.bcr-2018-225446.9","doi-asserted-by":"crossref","first-page":"542","DOI":"10.1067\/mjd.2003.99","article-title":"Anti-epiligrin cicatricial pemphigoid and epidermolysis bullosa acquisita: differentiation by use of indirect immunofluorescence microscopy","volume":"48","author":"Vodegel","year":"2003","journal-title":"J Am Acad Dermatol"},{"key":"2025042703573357000_2018.jun21_1.bcr-2018-225446.10","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/j.dsi.2011.05.003","article-title":"Differentiating antiepiligrin cicatricial pemphigoid from epidermolysis bullosa acquisita by indirect immunofluorescence of skin substrates lacking Type VII collagen or laminin 332: a case report and review of literature","volume":"29","author":"Chen","year":"2011","journal-title":"Dermatologica Sinica"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2018-225446","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,27]],"date-time":"2025-04-27T10:57:39Z","timestamp":1745751459000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2018-225446"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,6,21]]},"references-count":10,"alternative-id":["10.1136\/bcr-2018-225446"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2018-225446","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2018,6,21]]}}}