{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,22]],"date-time":"2026-01-22T13:26:18Z","timestamp":1769088378058,"version":"3.49.0"},"reference-count":5,"publisher":"BMJ","issue":"1","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2018,11,21]]},"published-print":{"date-parts":[[2018,11]]},"abstract":"<jats:p>Acute disseminated encephalomyelitis (ADEM) is a rare inflammatory-demyelinating disease of central nervous system. Several viral infections and vaccines act as precipitating factor for ADEM. We report an 8-year-old girl presenting with acute-onset flaccid paraparesis and bilateral painless vision loss. MRI brain showed extensive multifocal patchy demyelination and she made good clinical recovery with steroids and intravenous immunoglobulin therapy. She had history of bilateral parotid swelling before the onset of neurological symptoms and diagnosis of mumps was confirmed by positive ELISA in serum. Mumps, usually a benign and self-limited viral infection, rarely can cause severe neurological complications. Hence, we report this case to emphasise the importance of mumps vaccination and the need to strengthen the health policy system for the prevention of disease.<\/jats:p>","DOI":"10.1136\/bcr-2018-225710","type":"journal-article","created":{"date-parts":[[2018,12,28]],"date-time":"2018-12-28T04:55:14Z","timestamp":1545972914000},"page":"e225710","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":8,"title":["Acute disseminated encephalomyelitis: complication of a vaccine preventable disease"],"prefix":"10.1136","volume":"11","author":[{"given":"Arundhati","family":"Banerjee","sequence":"first","affiliation":[{"name":"Pediatric Neurology Unit, Department of Pediatrics, Advanced Pediatric Center, Post Graduate Institute of Medical education and Research, Chandigarh, Chandigarh, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4701-6168","authenticated-orcid":false,"given":"Renu","family":"Suthar","sequence":"additional","affiliation":[{"name":"Pediatric Neurology Unit, Department of Pediatrics, Advanced Pediatric Center, Post Graduate Institute of Medical Education and Research, Chandigarh, Chandigarh, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sameer","family":"Vyas","sequence":"additional","affiliation":[{"name":"Department of Radiodiagnosis and imaging, Post Graduate Institute of Medical Education and Research, Chandigarh, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mini P","family":"Singh","sequence":"additional","affiliation":[{"name":"Department of Virology, Post Graduate Institute of Medical Education and Research, Chandigarh, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2018,12,27]]},"reference":[{"key":"2025082803534917000_11.1.e225710.1","doi-asserted-by":"crossref","first-page":"724","DOI":"10.1007\/s12098-017-2351-z","article-title":"Mumps associated acute motor axonal polyneuropathy","volume":"84","author":"Didel","year":"2017","journal-title":"Indian J Pediatr"},{"key":"2025082803534917000_11.1.e225710.2","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.62.11.1673"},{"key":"2025082803534917000_11.1.e225710.3","doi-asserted-by":"crossref","DOI":"10.1212\/WNL.0b013e3181c2eee3","article-title":"Teaching NeuroImages: Acute hemorrhagic leukoencephalitis after mumps","volume":"73","author":"Kumar R","year":"2009","journal-title":"Neurology"},{"key":"2025082803534917000_11.1.e225710.4","doi-asserted-by":"crossref","first-page":"892","DOI":"10.4103\/2249-4863.201170","article-title":"Acute disseminated encephalomyelitis after mumps infection","volume":"5","author":"Jha","year":"2016","journal-title":"J Family Med Prim Care"},{"key":"2025082803534917000_11.1.e225710.5","doi-asserted-by":"crossref","first-page":"2076","DOI":"10.1002\/ebch.1948","article-title":"Vaccines for measles, mumps and rubella in children","volume":"8","author":"Demicheli","year":"2013","journal-title":"Evidence-Based Child Health: A Cochrane Review Journal"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2018-225710","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T10:53:57Z","timestamp":1756378437000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2018-225710"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,11]]},"references-count":5,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2018,12,27]]},"published-print":{"date-parts":[[2018,11]]}},"alternative-id":["10.1136\/bcr-2018-225710"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2018-225710","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,11]]}}}