{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T20:52:40Z","timestamp":1772225560118,"version":"3.50.1"},"reference-count":9,"publisher":"BMJ","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Reports"],"accepted":{"date-parts":[[2018,8,13]]},"abstract":"<jats:p>This case describes a female patient with a history of breast cancer who presented with a persistent cough and weight loss after a 17-year disease-free period. Radiologically there were new bilateral intrapulmonary nodules and areas of consolidation with a broad differential diagnosis. Brushings gained via bronchoscopy were suggestive of malignancy, but subsequent video-assisted thoracoscopic surgery wedge resection demonstrated organising pneumonia (OP) with no evidence of malignancy. Diagnostic uncertainty remained after this, and after a period of observation, there was evidence of disease progression. Further tissue was obtained for cytological and histological assessment which provided conclusive evidence of metastatic breast cancer. In this case, OP was secondary to proximal bronchial obstruction due to metastatic infiltration, of which there are no reported similar cases in the current literature. We discuss the importance of differentiating secondary OP from cryptogenic OP.<\/jats:p>","DOI":"10.1136\/bcr-2018-225771","type":"journal-article","created":{"date-parts":[[2018,8,29]],"date-time":"2018-08-29T12:19:52Z","timestamp":1535545192000},"page":"bcr-2018-225771","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":2,"title":["Breast cancer and organising pneumonia: the importance of correlating the pathological findings with the clinical and radiological picture"],"prefix":"10.1136","volume":"2018","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4077-5949","authenticated-orcid":false,"given":"Paul","family":"Griffiths","sequence":"first","affiliation":[{"name":"Department of Respiratory Medicine, Mid Cheshire Hospitals NHS Foundation Trust, Crewe, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Helen","family":"Doran","sequence":"additional","affiliation":[{"name":"Department of Pathology, University Hospital of South Manchester NHS Foundation Trust, Manchester, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Duncan","family":"Fullerton","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine, Mid Cheshire Hospitals NHS Foundation Trust, Crewe, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2018,8,29]]},"reference":[{"key":"2025082804071383000_2018.aug29_1.bcr-2018-225771.1","doi-asserted-by":"publisher","DOI":"10.1148\/rg.337130057"},{"key":"2025082804071383000_2018.aug29_1.bcr-2018-225771.2","doi-asserted-by":"crossref","first-page":"506","DOI":"10.3389\/fimmu.2017.00506","article-title":"Immunological aspect of radiation-induced pneumonitis, current treatment strategies, and future prospects","volume":"8","author":"Kainthola","year":"2017","journal-title":"Front Immunol"},{"key":"2025082804071383000_2018.aug29_1.bcr-2018-225771.3","doi-asserted-by":"publisher","DOI":"10.1634\/theoncologist.2014-0041"},{"key":"2025082804071383000_2018.aug29_1.bcr-2018-225771.4","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1093\/jrr\/rry001","article-title":"Incidence of organizing pneumonia after whole-breast radiotherapy for breast cancer, and risk factor analysis","volume":"59","author":"Sato","year":"2018","journal-title":"J Radiat Res"},{"key":"2025082804071383000_2018.aug29_1.bcr-2018-225771.5","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.03.00035502"},{"key":"2025082804071383000_2018.aug29_1.bcr-2018-225771.6","doi-asserted-by":"crossref","first-page":"229","DOI":"10.3892\/mco.2016.1113","article-title":"Interstitial lung disease associated with trastuzumab monotherapy: a report of 3 cases","volume":"6","author":"Sugaya","year":"2017","journal-title":"Mol Clin Oncol"},{"key":"2025082804071383000_2018.aug29_1.bcr-2018-225771.7","doi-asserted-by":"crossref","first-page":"747","DOI":"10.15537\/smj.2015.6.11305","article-title":"Saddle pulmonary embolus and bronchiolitis obliterans with organizing pneumonia develop simultaneously after first cyclophosphamide, methotrexate, 5FU chemotherapy for breast cancer","volume":"36","author":"Al-Hameed","year":"2015","journal-title":"Saudi Med J"},{"key":"2025082804071383000_2018.aug29_1.bcr-2018-225771.8","first-page":"394","article-title":"Organising pneumonia and lung cancer - case report and review of the literature","volume":"75","author":"Radzikowska","year":"2007","journal-title":"Pneumonol Alergol Pol"},{"key":"2025082804071383000_2018.aug29_1.bcr-2018-225771.9","first-page":"39","article-title":"Cryptogenic organizing pneumonia masquerading as lung carcinoma: a case report and review of the literature","volume":"15","author":"Huo","year":"2018","journal-title":"Exp Ther Med"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2018-225771","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T11:07:23Z","timestamp":1756379243000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2018-225771"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,8,29]]},"references-count":9,"alternative-id":["10.1136\/bcr-2018-225771"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2018-225771","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,8,29]]}}}