{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,24]],"date-time":"2025-09-24T10:22:25Z","timestamp":1758709345975,"version":"3.44.0"},"reference-count":13,"publisher":"BMJ","issue":"1","license":[{"start":{"date-parts":[[2018,11,1]],"date-time":"2018-11-01T00:00:00Z","timestamp":1541030400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.bmj.com\/company\/legal-information\/terms-conditions\/legal-information\/tdm-licencepolicy"}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2018,10,9]]},"published-print":{"date-parts":[[2018,11]]},"abstract":"<jats:p>Juvenile papillomatosis is a benign epithelial proliferative tumour of young women. It was recognised as a distinct clinicopathological entity with defining criteria by Rosen <jats:italic>et al<\/jats:italic> since 1980. However, giant juvenile papillomatosis is rare. We report a case of a 14-year-old girl who presented to our institution\u2019s breast clinic with a huge right breast mass measuring 20\u2009cm \u00d7 15\u2009cm. She had no personal history of previous breast disease and there was no family history of breast cancer. Our initial preoperative diagnosis was of a phylloides tumour. The patient had a total excision of her breast mass which revealed florid juvenile papillomatosis at histology. This presentation highlights the clinical presentation and imaging features of juvenile papillomatosis. The classical histopathological characteristics, unusual microscopic findings and management of a huge-sized tumour in an adolescent Nigerian patient are also presented.<\/jats:p>","DOI":"10.1136\/bcr-2018-225993","type":"journal-article","created":{"date-parts":[[2018,12,18]],"date-time":"2018-12-18T17:19:47Z","timestamp":1545153587000},"page":"e225993","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":3,"title":["Giant juvenile papillomatosis of the breast in a Nigerian girl"],"prefix":"10.1136","volume":"11","author":[{"given":"Sefiya Adebanke","family":"Olarinoye-Akorede","sequence":"first","affiliation":[{"name":"Radiology, Ahmadu Bello University Teaching Hospital, Zaria, Nigeria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bilkisu","family":"Farouk","sequence":"additional","affiliation":[{"name":"Radiology, Barau Dikko Teaching Hospital Kaduna, Kaduna, Nigeria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Almustapha Aliyu","family":"Liman","sequence":"additional","affiliation":[{"name":"Histopathology, Ahmadu Bello University Teaching Hospital, Zaria, Nigeria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gbenga Abimbola","family":"Kajogbola","sequence":"additional","affiliation":[{"name":"Radiology, ASI Ukpo Diagnostic and Medical Center, Calabar, Nigeria"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2018,12,14]]},"reference":[{"key":"2025082622540952000_11.1.e225993.1","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-198002000-00001"},{"key":"2025082622540952000_11.1.e225993.2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19820615)49:12<2591::AID-CNCR2820491230>3.0.CO;2-O"},{"key":"2025082622540952000_11.1.e225993.3","doi-asserted-by":"crossref","first-page":"51","DOI":"10.5152\/ejbh.2017.3828","article-title":"Juvenile papillomatosis of the breast in a pre-pubertal girl: an uncommon diagnosis","volume":"14","author":"Kafadar","year":"2018","journal-title":"Eur J Breast Health"},{"key":"2025082622540952000_11.1.e225993.4","first-page":"116","article-title":"Giant juvenile papillomatosis of the breast: report of two cases","volume":"74","author":"Farid","year":"1997","journal-title":"East Afr Med J"},{"key":"2025082622540952000_11.1.e225993.5","first-page":"99","article-title":"Papillomatosis and breast cancer: a case report and a review of the literature","volume":"4","author":"Batori","year":"2000","journal-title":"Eur Rev Med Pharmacol Sci"},{"key":"2025082622540952000_11.1.e225993.6","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19850315)55:6<1345::AID-CNCR2820550631>3.0.CO;2-B"},{"key":"2025082622540952000_11.1.e225993.7","doi-asserted-by":"crossref","first-page":"2587","DOI":"10.3892\/ol.2014.2600","article-title":"Bifocal juvenile papillomatosis as a marker of breast cancer: A case report and review of the literature","volume":"8","author":"Wang","year":"2014","journal-title":"Oncol Lett"},{"key":"2025082622540952000_11.1.e225993.8","doi-asserted-by":"publisher","DOI":"10.1093\/ajcp\/93.5.599"},{"key":"2025082622540952000_11.1.e225993.9","first-page":"5027","article-title":"Combination of juvenile papillomatosis, juvenile fibroadenoma and intraductal carcinoma of the breast in a 15-year-old girl","volume":"35","author":"Sedloev","year":"2015","journal-title":"Anticancer Res"},{"key":"2025082622540952000_11.1.e225993.10","doi-asserted-by":"publisher","DOI":"10.1016\/j.jsurg.2007.03.007"},{"key":"2025082622540952000_11.1.e225993.11","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1093\/ajcp\/aqw161.032","article-title":"Juvenile papillomatosis of breast (\u201cswiss cheese disease\u201d) occurs more commonly in adults than in \u201cJuveniles\u201d","volume":"146","author":"Patel","year":"2016","journal-title":"Am J Clin Pathol"},{"key":"2025082622540952000_11.1.e225993.12","doi-asserted-by":"publisher","DOI":"10.1093\/ajcp\/86.6.745"},{"key":"2025082622540952000_11.1.e225993.13","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1007\/BF02966694","article-title":"A case of multiple juvenile papillomatosis of the breast and its immunohistochemical pathology","volume":"5","author":"Nio","year":"1998","journal-title":"Breast Cancer"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/data.bmj.org\/tdm\/10.1136\/bcr-2018-225993","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2018-225993","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T05:54:20Z","timestamp":1756274060000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2018-225993"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,11]]},"references-count":13,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2018,12,14]]},"published-print":{"date-parts":[[2018,11]]}},"alternative-id":["10.1136\/bcr-2018-225993"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2018-225993","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2018,11]]}}}