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We report a case of CVID complicated by HPS that was successfully treated with orthotopic liver transplant, with the patient recovering to normal hepatic function and successfully weaning off domiciliary oxygen post-transplantation.<\/jats:p>","DOI":"10.1136\/bcr-2018-226095","type":"journal-article","created":{"date-parts":[[2019,4,4]],"date-time":"2019-04-04T04:31:51Z","timestamp":1554352311000},"page":"e226095","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":10,"title":["Successful liver transplantation in common variable immune deficiency with reversal of hepatopulmonary syndrome"],"prefix":"10.1136","volume":"12","author":[{"given":"Ross","family":"Apostolov","sequence":"first","affiliation":[{"name":"Liver Transplant Unit, Austin Health, Heidelberg, Victoria, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marie","family":"Sinclair","sequence":"additional","affiliation":[{"name":"Liver Transplant Unit, Austin Health, Heidelberg, Victoria, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julie","family":"Lokan","sequence":"additional","affiliation":[{"name":"Department of Pathology, Austin Health, Heidelberg, Victoria, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter","family":"Angus","sequence":"additional","affiliation":[{"name":"Liver Transplant Unit, Austin Health, Heidelberg, Victoria, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2019,4,3]]},"reference":[{"key":"2025082712290081000_12.4.e226095.1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2007.08.011"},{"key":"2025082712290081000_12.4.e226095.2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2249.2008.03711.x"},{"key":"2025082712290081000_12.4.e226095.3","doi-asserted-by":"crossref","first-page":"748","DOI":"10.1007\/s10875-013-9873-6","article-title":"Nodular regenerative hyperplasia in common variable immunodeficiency","volume":"33","author":"Fuss","year":"2013","journal-title":"J Clin Immunol"},{"key":"2025082712290081000_12.4.e226095.4","doi-asserted-by":"crossref","first-page":"1708","DOI":"10.1016\/j.jaci.2016.10.025","article-title":"Liver transplantation in patients with primary antibody deficiency","volume":"139","author":"J\u00f8rgensen","year":"2017","journal-title":"J Allergy Clin Immunol"},{"key":"2025082712290081000_12.4.e226095.5","doi-asserted-by":"crossref","first-page":"E210","DOI":"10.1111\/j.1399-3046.2011.01545.x","article-title":"Liver transplantation for severe hepatitis in patients with common variable immunodeficiency","volume":"16","author":"Murakawa","year":"2012","journal-title":"Pediatr Transplant"},{"key":"2025082712290081000_12.4.e226095.6","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1007\/s10875-015-0142-8","article-title":"Familial hepatopulmonary syndrome in common variable immunodeficiency","volume":"35","author":"Holmes","year":"2015","journal-title":"J Clin Immunol"},{"key":"2025082712290081000_12.4.e226095.7","doi-asserted-by":"crossref","first-page":"1654","DOI":"10.4045\/tidsskr.11.0110","article-title":"[A man in his 60s with severe respiratory failure]","volume":"131","author":"Naalsund","year":"2011","journal-title":"Tidsskr Nor Laegeforen"},{"key":"2025082712290081000_12.4.e226095.8","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-6143.2009.02822.x"},{"key":"2025082712290081000_12.4.e226095.9","doi-asserted-by":"publisher","DOI":"10.1053\/jlts.2002.35544"},{"key":"2025082712290081000_12.4.e226095.10","doi-asserted-by":"crossref","first-page":"541","DOI":"10.12659\/AOT.890952","article-title":"Liver transplantation in patients with common variable immunodeficiency: a report of two cases","volume":"19","author":"Montalti","year":"2014","journal-title":"Ann Transplant"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2018-226095","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T19:29:09Z","timestamp":1756322949000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2018-226095"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,4]]},"references-count":10,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2019,4,3]]},"published-print":{"date-parts":[[2019,4]]}},"alternative-id":["10.1136\/bcr-2018-226095"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2018-226095","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2019,4]]}}}