{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T09:40:02Z","timestamp":1756374002782,"version":"3.44.0"},"reference-count":19,"publisher":"BMJ","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Reports"],"accepted":{"date-parts":[[2018,9,11]]},"abstract":"<jats:p>To report a case of retinoblastoma presenting as haemorrhagic choroidal detachment in a 10-year-old girl. The patient, apparently well, presented with sudden blurring of vision in the setting of blunt trauma. On examination and ocular ultrasound, haemorrhagic choroidal detachment was suspected. She underwent external drainage via sclerostomies. The haemorrhage resolved ultrasonographically, but the vision did not improve. Five months postoperatively, she presented with sudden eye pain, lid swelling and proptosis. The ancillary workups were consistent with panophthalmitis and was treated as such. Six months postoperatively, the pain and lid swelling persisted; hence, the painful near absolute eye was enucleated. The histopathology revealed small round blue cells with necrosis consistent with retinoblastoma. Immunohistochemistry was positive for synaptophysin and negative for S100 confirming retinoblastoma. Retinoblastoma is the most common intraocular malignancy in children. The importance of increased awareness of its various presentations is of utmost importance to prevent life-threatening and vision-impairing complications.<\/jats:p>","DOI":"10.1136\/bcr-2018-226149","type":"journal-article","created":{"date-parts":[[2018,10,25]],"date-time":"2018-10-25T02:37:08Z","timestamp":1540435028000},"page":"bcr-2018-226149","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":1,"title":["Retinoblastoma presenting as haemorrhagic choroidal detachment in a 10-year-old girl"],"prefix":"10.1136","volume":"2018","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1306-3727","authenticated-orcid":false,"given":"George Michael Ngo","family":"Sosuan","sequence":"first","affiliation":[{"name":"Department of Ophthalmology and Visual Sciences, College of Medicine and Philippine General Hospital, University of the Philippines Manila, Manila, Philippines"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jazel T","family":"Eleazar-Verde","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology and Visual Sciences, College of Medicine and Philippine General Hospital, University of the Philippines Manila, Manila, Philippines"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gary John V","family":"Mercado","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology and Visual Sciences, College of Medicine, University of the Philippines Manila, Manila, Philippines"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Milagros H","family":"Arroyo","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology and Visual Sciences, College of Medicine, University of the Philippines Manila, Manila, Philippines"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2018,10,24]]},"reference":[{"key":"2025082802001264000_2018.oct24_1.bcr-2018-226149.1","first-page":"7","article-title":"Understanding retinoblastoma: epidemiology and genetics","volume":"31","author":"Fabian","year":"2018","journal-title":"Community Eye Health"},{"key":"2025082802001264000_2018.oct24_1.bcr-2018-226149.2","doi-asserted-by":"publisher","DOI":"10.1111\/ceo.12132"},{"key":"2025082802001264000_2018.oct24_1.bcr-2018-226149.3","doi-asserted-by":"crossref","first-page":"632","DOI":"10.1097\/00003226-200208000-00026","article-title":"Spontaneous expulsive suprachoroidal hemorrhage","volume":"21","author":"Sudhir","year":"2002","journal-title":"Cornea"},{"key":"2025082802001264000_2018.oct24_1.bcr-2018-226149.4","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1590\/S0004-27492013000400003","article-title":"The surgical management of massive intraoperative and postoperative suprachoroidal hemorrhage: anatomic and functional outcomes","volume":"76","author":"Lavinsky","year":"2013","journal-title":"Arq Bras Oftalmol"},{"key":"2025082802001264000_2018.oct24_1.bcr-2018-226149.5","doi-asserted-by":"crossref","DOI":"10.1097\/MD.0000000000008697","article-title":"Delayed suprachoroidal hemorrhage after cataract surgery: a case report and brief review of literature","volume":"97","author":"Song","year":"2018","journal-title":"Medicine"},{"key":"2025082802001264000_2018.oct24_1.bcr-2018-226149.6","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(99)90062-3"},{"key":"2025082802001264000_2018.oct24_1.bcr-2018-226149.7","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1097\/ICB.0b013e3182437da2","article-title":"Delayed suprachoroidal hemorrhage after cataract surgery","volume":"6","author":"Ghorayeb","year":"2012","journal-title":"Retin Cases Brief Rep"},{"key":"2025082802001264000_2018.oct24_1.bcr-2018-226149.8","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1038\/eye.2012.252","article-title":"Intraocular metastasis","volume":"27","author":"Cohen","year":"2013","journal-title":"Eye"},{"key":"2025082802001264000_2018.oct24_1.bcr-2018-226149.9","unstructured":"Kanski JJ , Bowling B . Kanski oftalmolog\u00eda cl\u00ednica. 7th edn. Espa\u00f1a: Elsevier, 2012:878."},{"key":"2025082802001264000_2018.oct24_1.bcr-2018-226149.10","doi-asserted-by":"crossref","first-page":"0028","DOI":"10.1007\/s004170050005","article-title":"Massive suprachoroidal hemorrhage: secondary treatment and outcome","volume":"238","author":"Meier","year":"2000","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"key":"2025082802001264000_2018.oct24_1.bcr-2018-226149.11","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.2003.026138"},{"key":"2025082802001264000_2018.oct24_1.bcr-2018-226149.12","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1001\/archopht.122.3.408","article-title":"Slowly progressive retinal arteriovenous malformation and relative amblyopia","volume":"122","author":"Ehrt","year":"2004","journal-title":"Arch Ophthalmol"},{"key":"2025082802001264000_2018.oct24_1.bcr-2018-226149.13","doi-asserted-by":"publisher","DOI":"10.1038\/eye.2009.310"},{"key":"2025082802001264000_2018.oct24_1.bcr-2018-226149.14","first-page":"e10","article-title":"Iris hypoplasia as the presenting signs of retinoblastoma in a child with a 13q deletion","volume":"55","author":"Shah","year":"2018","journal-title":"J Pediatr Ophthalmol Strabimus"},{"key":"2025082802001264000_2018.oct24_1.bcr-2018-226149.15","doi-asserted-by":"crossref","first-page":"66","DOI":"10.11604\/pamj.2017.28.66.11199","article-title":"Presenting signs of retinoblastoma at a tertiary level teaching hospital in Ethiopia","volume":"28","author":"Shifa","year":"2017","journal-title":"Pan Afr Med J"},{"key":"2025082802001264000_2018.oct24_1.bcr-2018-226149.16","unstructured":"Murthy R , Honavar SG , Naik MN , et al . Retinoblastoma. In: Dutta LC , ed. Modern ophthalmology. New Delhi, India: Jaypee Brothers, 2004:849859."},{"key":"2025082802001264000_2018.oct24_1.bcr-2018-226149.17","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1159\/000441528","article-title":"Clinical presentation and genetic paradigm of diffuse infiltrating retinoblastoma: a review","volume":"2","author":"Traine","year":"2016","journal-title":"Ocul Oncol Pathol"},{"key":"2025082802001264000_2018.oct24_1.bcr-2018-226149.18","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.2010.193961"},{"key":"2025082802001264000_2018.oct24_1.bcr-2018-226149.19","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1016\/j.sjopt.2013.11.001","article-title":"Retinoblastoma: an overview","volume":"28","author":"Pandey","year":"2014","journal-title":"Saudi J Ophthalmol"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2018-226149","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T09:00:31Z","timestamp":1756371631000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2018-226149"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,10,24]]},"references-count":19,"alternative-id":["10.1136\/bcr-2018-226149"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2018-226149","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2018,10,24]]}}}