{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,6]],"date-time":"2025-11-06T12:19:27Z","timestamp":1762431567973,"version":"3.44.0"},"reference-count":29,"publisher":"BMJ","issue":"1","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2018,12,17]]},"published-print":{"date-parts":[[2019,1]]},"abstract":"<jats:p>Solid papillary thyroid carcinoma (SV-PTC) is a rare variant which is mainly observed in young patients with a history of exposure to ionising radiations. Neoplasms belonging to such category generally carry RET-PTC (REarranged during Transfection- Papillary Thyroid Carcinoma) fusions and seem to have a slightly worse prognosis with respect to classical and follicular variants of papillary thyroid carcinoma (PTC), though consistent prognostic and survival data are scarce. SV-PTC should be differentiated from trabecular-insular poorly differentiated thyroid carcinomas, which occur in a different age group and carry a dismal prognosis. These latter tumours do not show the typical nuclear features of PTC and show tumour necrosis with an high mitotic activity. In this report a further case of SV-PTC is described which was associated to Hashimoto\u2019s thyroiditis, a finding never described in the cytological literature up to now for SV-PTC; this association created further differential diagnostic problems. The neoplasm displayed RET-PTC1 fusion.<\/jats:p>","DOI":"10.1136\/bcr-2018-226153","type":"journal-article","created":{"date-parts":[[2019,1,18]],"date-time":"2019-01-18T04:20:03Z","timestamp":1547785203000},"page":"e226153","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":5,"title":["Solid papillary thyroid carcinoma with Hashimoto\u2019s thyroiditis: description of a further case with challenging cytological features"],"prefix":"10.1136","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4244-1109","authenticated-orcid":false,"given":"Franco","family":"Fulciniti","sequence":"first","affiliation":[{"name":"Pathology, Institute of Pathology, Locarno, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jessica","family":"Barizzi","sequence":"additional","affiliation":[{"name":"Pathology, Institute of Pathology, Locarno, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pierpaolo","family":"Trimboli","sequence":"additional","affiliation":[{"name":"Department of Nuclear Medicine and Thyroid Centre, Oncology Institute of Southern Switzerland, Bellinzona, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luca","family":"Giovanella","sequence":"additional","affiliation":[{"name":"Department of Nuclear Medicine and Thyroid Centre, Oncology Institute of Southern Switzerland, Bellinzona, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2019,1,17]]},"reference":[{"key":"2025082704071415000_12.1.e226153.1","unstructured":"Rosai J , Albores Saavedra J , Asioli S . 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